Cleveland Clinic’s Sarcoma Program is a national and international resource for the diagnosis and treatment of adults and children with benign and malignant tumors of the bone and soft tissue.
The multidisciplinary sarcoma clinic is designed to provide you with the medical opinions of sarcoma specialists from different disciplines in a single location. Sarcoma surgeons, medical oncologists, radiation oncologists, radiologists and pathologists come together to review patients with malignant and benign bone and soft tissue tumors. These sarcoma specialists are experienced in the care of complex, challenging tumors. Together, they will come up with the treatment plan most likely to result in the best possible outcome and quality of life.
People who develop cancer of the bone or surrounding soft tissue can take comfort in Cleveland Clinic's expertise with musculoskeletal cancers. Although bone tumors are relatively rare, our specialists treat hundreds of people with benign and malignant tumors each year in one of the largest programs in the United States.
In the past, bone cancer often led to amputation. Today, our bone cancer specialists have reversed that trend with limb-sparing surgery at Cleveland Clinic. More than 90 percent of our patients with bone cancer can avoid amputation with only a small chance of recurrence.
Cleveland Clinic is ranked as one of the nation’s top hospitals by U.S. News & World Report.
What We Treat
- Clear Cell Sarcoma
- Desmoplastic Small Round Cell Tumor
- Epithelial Sarcoma
- Ewing Sarcoma
- Gastrointestinal Stromal Sarcoma (GIST)
- Giant Cell Tumors
- Malignant Bone
- Malignant Soft Tissue Tumors
- Malignant peripheral nerve sheath tumors
- Metastatic Bone Tumors
- Soft tissue sarcoma (adult)
- Soft tissue sarcoma (childhood)
- Solitary Fibrous Tumor
- Synovial Sarcoma
- Undifferentiated Pleomorphic Sarcoma (previously called malignant fibrous histiocytoma)
Benign Bone Tumors
- Benign Bone Tumors
- Blood Cell Tumors
- Osteosclerotic Myeloma
- Solitary Bone Plasmacytoma
- Cartilage Tumors
- Chondromyxoid Fibroma
- Multiple Enchondromatosis (Ollier's Disease, Maffucci's Syndrome)
- Multiple Hereditary Exostosis
- Periosteal Chondroma
- Solitary Enchondroma
- Solitary Osteochondroma
- Conditions Which Can Be Mistaken For Tumors
- Fibrogenic & Histiocytic Tumors
- Desmoplastic Fibroma
- Histiocytoma/Benign Fibrous Histiocytoma
- Multiple non-ossifying fibromas (Jaffe-Campanacci Syndrome, Familial Multifocal NOF)
- Solitary non-ossifying fibroma
- Giant Cell Tumor (also known as Osteoclastoma)
- Osseous Tumors
- Osteoid Osteoma
- Reactive Lesions
- Aneurysmal Bone Cyst
- Unicameral Bone Cyst
- Tumor-like Lesions
- Bone Infarct
- Bone Island (also known as Enostosis)
- Brown Tumor of Hyperparathyroidism
- Eosinophilic Granuloma
- Fibrodysplasia Ossificans Progressiva (Munchmeyer's Disease)
- Fibrous Dysplasia (McCune Albright Syndrome, Mazabraud Syndrome, Osteofibrous Dysplasia)
- Focal Fibrocartilaginous Dysplasia
- Heterotopic Ossification
- Myositis Ossificans
- Osteofibrous Dysplasia (also known as Ossifying Fibroma, Campanacci Lesion)
- Paget's Disease
- Synovial Osteochondromatosis
- Tumoral Calcinosis
- Vascular Tumors
- Hemangioma of Bone
Benign Soft Tissue Tumors
- Benign Soft Tissue Tumors
- Fatty Tumors
- Intramuscular Lipoma
- Pleomorphic Lipoma
- Spindle Cell Lipoma
- Fibrogenic Tumors
- Calcifying Aponeurotic Fibroma
- Extra-abdominal Desmoid Tumor (Familial Adenomatous Polyposis, Gardner Syndrome)
- Nodular Fasciitis
- Plantar Fibromatosis (Ledderhose Disease)
- Muscular Tumors
- Intramuscular Myxoma (Mazabraud's Syndrome)
- Peripheral Nerve Tumors
- Neurilemmoma (also known as Schwannoma)
- Neuroma (including Morton's Neuroma)
- Sporadic Neurofibromas
- Synovial Tumors
- Giant Cell Tumor of Tendon Sheath
- Pigmented Villonodular Synovitis
- Synovial Chondromatosis
- Vascular Tumors
- Glomus Tumor (also known as Paraganglioma)
- Intramuscular Hemangioma
For Additional Information
Support & Services
In addition to offering state of the art diagnostic techniques and sarcoma treatment methods, our sarcoma specialists offer an array of resources that can help patients cope with the demands of cancer. Patients are encouraged to take advantage of these resources to ease the burden of managing cancer.
- Second Opinion Keeps Cancer Fighter Enjoying The Outdoors
- Survivor Connects With Others Through Humor and Positivity
- Husband Fighting Rare Cancer After Wife Persisted He Seek Second Opinion
Clinical Trials & Research
Cleveland Clinic Cancer Center clinical trials offer patients important sarcoma treatment options and access to the latest treatments and procedures resulting from cancer research.
Clinical trials (or research studies) help us create the medicine of tomorrow. They provide hope through offering testing of new drugs, new surgical techniques or other treatments before they are widely available.
We can help you access hundreds of clinical trials across all specialty areas. Our new searchable online trials tool makes identifying treatment opportunities easier than ever.
Cleveland Clinic Cancer Center is committed to working with you to provide the best care for your patients. Our team is also dedicated to the training and education of medical professionals to advance cancer care and research.
Pathology Second Opinion
Cleveland Clinic Laboratories offers second opinion pathology consultations for surgical pathology, cytology, and hematopathology cases.
Make An Online Referral to Cleveland Clinic Cancer Center
You will receive confirmation once the appointment is scheduled.
To refer a surgical patient, please contact our Referring Physician Hotline, available 24 hours a day, 7 days a week, for all your needs, by calling 855.REFER.123 (855.733.3712).