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Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Airway Stenosis Treatment
  • Cancer Center
  • Endoscopic Pituitary Surgery
  • Endoscopic Skull Base Surgery
  • Endoscopic Zenker's Diverticulum Surgery
  • Facial Reanimation
  • Head and Neck Cancer Surgery
  • Head And Neck Cancer Treatment
  • Head and Neck Endocrine Surgery
  • Head and neck reconstructive surgery
  • Laser Surgery
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Reconstructive Head And Neck Surgery
  • Reconstructive Surgery of the Face
  • Robotic Surgery
  • Salivary Gland Surgery
  • Sialoendoscopy
  • Tracheal Resection
  • Tracheostomy
  • Tracheostomy Care
  • Tracheotomy
  • Transsphenoidal Pituitary Surgery
  • Ultrasound-guided Procedures
  • Vocal Cord Paralysis Treatment
View all 25 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult Airway Reconstruction
  • Adult and Pediatric Facial Trauma
  • Airway Obstruction and Tracheotomy
  • Benign Maxillofacial Tumors
  • Benign Skull Base Tumors
  • Benign Tumors Of The Head
  • Benign Tumors Of The Neck
  • Carotid Body Tumor
  • Dysphagia
  • Esthesioneuroblastoma
  • Facial Trauma
  • Glomus Tumors
  • Glomus Vagale Tumors
  • Head and Neck Cancer
  • Head and Neck Masses
  • Head and Neck Paragangliomas
  • Head and Neck Trauma
  • Head And Neck Tumors
  • Hypopharyngeal Cancer
  • Laryngeal Cancer
  • Laryngeal Stenosis
  • Laryngeal Tracheal Reconstruction
  • Lip and Oral Cavity Cancer
  • Malignant Head and Neck Disease
  • Malignant Tumors Of The Head
  • Malignant Tumors Of The Neck
  • Melanoma
  • Minor Salivary Gland Cancer
  • Nasal Cavity Cancer
  • Nasopharyngeal Cancer
  • Oropharyngeal Cancer
  • Paraganglioma
  • Parathyroid Cancer
  • Parotid Cancer
  • Pediatric Head And Neck Cancer
  • Pituitary Tumors
  • Rare Cancer and Blood Disease Program
  • Salivary Gland Cancer
  • Salivary Gland Diseases
  • Salivary Gland Neoplasms
  • Sarcoma
  • Sinonasal Tumors
  • Skull Base Cancer
  • Subglottic Stenosis
  • Submandibular Gland Cancer
  • Thyroid Cancer
  • Thyroid Masses
  • Thyroid Nodule
  • Tracheal Stenosis
  • Tracheoesophageal Fistula
  • Vocal Cord Paralysis
  • Zenker's Diverticulum
View all 52 Specialties +


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About Brandon Prendes, M.D.

Brandon Prendes, MD, is a surgeon in the Cleveland Clinic's Head and Neck Institute and a Staff Member of both the Section of Head and Neck Surgery and the Section of Facial Plastic and Reconstructive Surgery. He is board-certified by the State of Ohio Medical Board and the American Board of Otolaryngology. His specialty interests include head and neck cancer surgery, microvascular reconstructive surgery, thyroid and parathyroid surgery, transoral robotic surgery, benign and malignant salivary tumors and diseases (including endoscopic removal of salivary gland stones), ultrasonography for diagnosis of head and neck tumors, sinonasal tumors, and skull base surgery.

Dr. Prendes' education includes a Bachelors of Science in Engineering, Summa Cum Laude, from the University of Michigan and a Medical Doctorate from the University of Pennsylvania School of Medicine. He completed a surgical internship and an Otolaryngology - Head and Neck Surgery Residency at the University of California San Francisco. He pursued further fellowship training in advanced head and neck cancer, endocrine, and microvascular reconstructive surgery at the Cleveland Clinic prior to joining the Head and Neck Institute as Professional Staff.

Dr. Prendes is a member of the American Academy of Otolaryngology - Head and Neck Surgery and of the American Head and Neck Society. He also serves as an educator teaching medical students, residents, and fellows. He has published a number of journal articles on topics ranging from the involvement of the human papilloma virus (HPV) in throat cancer to the endoscopic treatment of salivary gland diseases and has presented on these topics at national academic meetings.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Head & Neck Oncologic & Reconstructive Fellowship
Cleveland, OH USA

Residency - University of California-San Francisco
San Francisco, CA USA

Medical Education - University of Pennsylvania
Philadelphia, PA USA

Undergraduate - University of Michigan
Ann Arbor, MI USA


  • Otolaryngology

Specialty Interests

Robotic transoral surgery, airway stenosis, adult airway reconstruction, laryngeal and tracheal reconstruction, head and neck cancer, congenital and benign and malignant tumors of the head and neck, head and neck reconstructive surgery for cancer and for trauma, microvascular reconstructive surgery, head and neck endocrine (thyroid and parathyroid gland) surgery and malignant tumors, salivary gland tumors and cancer, skin cancer of the head and neck including melanoma, paranasal sinus tumors, skull base surgery, parapharyngeal space tumors, endoscopic treatment of salivary gland stones and diseases (sialendoscopy).

Awards & Honors

  • Western Section of the Triologic Society Vice President's Research Award
Research & Publications

Research & Publications

See publications for Brandon Prendes, M.D..

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/8/2021, Dr. Prendes has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

161 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.8
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

34 Patient Comments

Reviewed on Mar 11, 2021

overall great experience..appt availability is more of work load on Dr Prendes and I understand that there are limited time slots.

Reviewed on Mar 8, 2021

love the care provider

Reviewed on Feb 18, 2021

I really like Dr. Prendez. He takes his time with you and addresses your concerns.

Reviewed on Feb 10, 2021

The only downfall is the physician can't physically grab your tongue and look at it other than that it save me a 4 1/2 hour drive one way

Reviewed on Jan 8, 2021

Dr. Prendes is warm and pleasant. Very patient-oriented. He listens, which is the most important thing a doctor can do.

Reviewed on Jan 5, 2021

Dr. Prendes is one of the best doctors I have ever had.

Reviewed on Dec 9, 2020

Dr Prendes is a wonderful doctor who always takes time to answer my questions and explain things to me. He's the greatest!!!

Reviewed on Oct 22, 2020

it was a very good experience. Dr. Prendes was very kind and easy to speak with.

Reviewed on Sep 24, 2020

very well fine oiled machine from Valet parking to the doctors, very impressed with everyone receptionist nurses doctors and anyone else I dealt with

Reviewed on Sep 22, 2020

I couldn't of asked for any better group of doctors or staff they were awesome

Reviewed on Sep 9, 2020

I felt much better because Dr. Prendes answered all my questions.

Reviewed on Aug 20, 2020

Dr. Prendes as well was very apologetic of the delay, and I mentioned that I fully understood delays happen and am OK with it, it would have been nice to be notified while I'm in the waiting area, he expressed that he would look into it. Dr. Prendes is the best. He is very caring and I always feel like I'm getting the best care with him being my ENT doc. I feel very lucky to be under his care and guidance. He is very gentle with procedures and explains everything that has to be done, and the reason for it.

Reviewed on Aug 6, 2020

I have already recommended Dr. Trended to 3 other patients with excellent results.

Reviewed on Aug 6, 2020

Dr. Prendes is great!

Reviewed on Aug 4, 2020

I would recommend Dr. Prendes to anyone who was having problems with their thyroid. I really like him, he is very personable and knows his stuff.

Reviewed on Jul 30, 2020

Doctor and staff all excellent

Reviewed on Jul 28, 2020

Dr Prendes is an excellent care provider. we trust him 100%.

Reviewed on Jul 23, 2020

Dr Prendes was thorough, kind, and very professional.

Reviewed on Jul 8, 2020

Always good rapport *Dr. Prendes... he takes all the time necessary; never appears to rush us through...

Reviewed on Jul 8, 2020

*Dr. Prendes is consummate professional... very pleasant, understanding & kind... easy to interpret instructions...

Reviewed on Jun 30, 2020

I really enjoyed Dr. Prendas. He was very helpful. Didn't rush the vist. And was very concerned to keep me comfortable.

Reviewed on Jun 29, 2020

I actually referred a friend of mine to Dr Prendes at my visit and he is going to meet with him on Monday

Reviewed on Jun 22, 2020

Dr Prendes was excellent. I loved his demeanor,his attention to me, his safety with mask etc for me and his thorough exam and plan. I will definitely recommend Dr Prendes and return to him if necessary

Reviewed on Jun 22, 2020

I think in spite of COVID I was able to see a physician and have my needs met. Clinical staff is always excellent. I expected better attention to sanitizing waiting room area and valet services

Reviewed on Jun 18, 2020

This was my best experience ever with a medical provider. Dr Prendes is very calm, clear, and explains everything.

Reviewed on Jun 8, 2020

Dr. Prendes saved my life four years ago and he has kept watch on me ever since. His staff is also polite and very efficient.

Reviewed on Jun 8, 2020

I have nominate d Dr . Prendes for sainthood.

Reviewed on Jun 4, 2020

dr prendes and his resident were excellent!!

Reviewed on Jun 4, 2020

Dr Prendes is extremely professional and caring . I could not have better care.

Reviewed on Jun 1, 2020

Dr. Prendes is a true medical professional who consistently exceeds my expectations in providing care. I wish every patient could have an opportunity to experience a medical visit where in the doctor exhibits an effort to facilitate better health outcomes for their patients. the Clinic is fortunate to have him as a member of your medical staff.

Reviewed on May 21, 2020

From day one, I have been very impressed with Dr. Prendes. He makes me feel like my care is of upmost importance, and he has a demeaner that is very comforting and reassuring. He answers all my questions and has taken great care of me during my journey with my health issues.

Reviewed on May 14, 2020

Dr. Prendez remembers details about me that many doctors would not. He listens and pays attention to me.

Reviewed on Apr 28, 2020

Dr Prendes is wonderful.

Reviewed on Apr 2, 2020

Dr. Prendes has been my doctor for 5 years. He assisted in my cancer surgery and my last check up was this visit. I would like to do thank Dr. Prendes, all of the staff at the head and neck center and Cleveland Clinic for the wonderful care I received.

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