Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Airway Stenosis Treatment
  • Cancer Center
  • Endoscopic Pituitary Surgery
  • Endoscopic Skull Base Surgery
  • Endoscopic Zenker's Diverticulum Surgery
  • Facial Reanimation
  • Head and Neck Cancer Surgery
  • Head And Neck Cancer Treatment
  • Head and Neck Endocrine Surgery
  • Head and neck reconstructive surgery
  • Laser Surgery
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Reconstructive Head And Neck Surgery
  • Reconstructive Surgery of the Face
  • Robotic Surgery
  • Salivary Gland Surgery
  • Sialoendoscopy
  • Tracheal Resection
  • Tracheostomy
  • Tracheostomy Care
  • Tracheotomy
  • Transsphenoidal Pituitary Surgery
  • Ultrasound-guided Procedures
  • Vocal Cord Paralysis Treatment
View all 25 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult Airway Reconstruction
  • Adult and Pediatric Facial Trauma
  • Airway Obstruction and Tracheotomy
  • Benign Maxillofacial Tumors
  • Benign Skull Base Tumors
  • Benign Tumors Of The Head
  • Benign Tumors Of The Neck
  • Carotid Body Tumor
  • Dysphagia
  • Facial Trauma
  • Glomus Tumors
  • Glomus Vagale Tumors
  • Head and Neck Cancer
  • Head and Neck Masses
  • Head and Neck Paragangliomas
  • Head and Neck Trauma
  • Head And Neck Tumors
  • Hypopharyngeal Cancer
  • Laryngeal Cancer
  • Laryngeal Stenosis
  • Laryngeal Tracheal Reconstruction
  • Lip and Oral Cavity Cancer
  • Malignant Head and Neck Disease
  • Malignant Tumors Of The Head
  • Malignant Tumors Of The Neck
  • Melanoma
  • Minor Salivary Gland Cancer
  • Nasal Cavity Cancer
  • Nasopharyngeal Cancer
  • Oropharyngeal Cancer
  • Paraganglioma
  • Parathyroid Cancer
  • Parotid Cancer
  • Pediatric Head And Neck Cancer
  • Pituitary Tumors
  • Rare Cancer and Blood Disease Program
  • Salivary Gland Cancer
  • Salivary Gland Diseases
  • Salivary Gland Neoplasms
  • Sarcoma
  • Sinonasal Tumors
  • Skull Base Cancer
  • Subglottic Stenosis
  • Submandibular Gland Cancer
  • Thyroid Cancer
  • Thyroid Masses
  • Thyroid Nodule
  • Tracheal Stenosis
  • Tracheoesophageal Fistula
  • Vocal Cord Paralysis
  • Zenker's Diverticulum
View all 51 Specialties +


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About Brandon Prendes, M.D.

Brandon Prendes, MD, is a surgeon in the Cleveland Clinic's Head and Neck Institute and a Staff Member of both the Section of Head and Neck Surgery and the Section of Facial Plastic and Reconstructive Surgery. He is board-certified by the State of Ohio Medical Board and the American Board of Otolaryngology. His specialty interests include head and neck cancer surgery, microvascular reconstructive surgery, thyroid and parathyroid surgery, transoral robotic surgery, benign and malignant salivary tumors and diseases (including endoscopic removal of salivary gland stones), ultrasonography for diagnosis of head and neck tumors, sinonasal tumors, and skull base surgery.

Dr. Prendes' education includes a Bachelors of Science in Engineering, Summa Cum Laude, from the University of Michigan and a Medical Doctorate from the University of Pennsylvania School of Medicine. He completed a surgical internship and an Otolaryngology - Head and Neck Surgery Residency at the University of California San Francisco. He pursued further fellowship training in advanced head and neck cancer, endocrine, and microvascular reconstructive surgery at the Cleveland Clinic prior to joining the Head and Neck Institute as Professional Staff.

Dr. Prendes is a member of the American Academy of Otolaryngology - Head and Neck Surgery and of the American Head and Neck Society. He also serves as an educator teaching medical students, residents, and fellows. He has published a number of journal articles on topics ranging from the involvement of the human papilloma virus (HPV) in throat cancer to the endoscopic treatment of salivary gland diseases and has presented on these topics at national academic meetings.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Head & Neck Oncologic & Reconstructive Fellowship
Cleveland, OH USA

Residency - University of California-San Francisco
San Francisco, CA USA

Medical Education - University of Pennsylvania
Philadelphia, PA USA

Undergraduate - University of Michigan
Ann Arbor, MI USA


  • Otolaryngology

Specialty Interests

Robotic transoral surgery, airway stenosis, adult airway reconstruction, laryngeal and tracheal reconstruction, head and neck cancer, congenital and benign and malignant tumors of the head and neck, head and neck reconstructive surgery for cancer and for trauma, microvascular reconstructive surgery, head and neck endocrine (thyroid and parathyroid gland) surgery and malignant tumors, salivary gland tumors and cancer, skin cancer of the head and neck including melanoma, paranasal sinus tumors, skull base surgery, parapharyngeal space tumors, endoscopic treatment of salivary gland stones and diseases (sialendoscopy).

Awards & Honors

  • Western Section of the Triologic Society Vice President's Research Award
Research & Publications

Research & Publications

See publications for Brandon Prendes, M.D..

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/10/2019, Dr. Prendes has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

157 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 5
Courtesy, Respect & Concern 5
Knows Medical History 4.7
Time Spent with Patient 5
Patient Rating of Doctor 4.9

32 Patient Comments

Reviewed on Sep 12, 2019

Great doctor! Was wonderful at listening, informing, answering questions and follow up.

Reviewed on Aug 22, 2019

he is a wonderful Dr as well as a wonderful person. I am very confident in his care..

Reviewed on Aug 15, 2019

The clinic and Doctor Prendes in particular are the best

Reviewed on Aug 15, 2019

Dr. Prendes is a consumate professional as well as a caring person. I trust his judgement,skillset, and expertise. Would reccomend him to anyone, family or friend alike.

Reviewed on Jul 8, 2019


Reviewed on Jul 2, 2019

I will recommend Dr. Prendes to everyone. I'm not treated as another person in his schedule, and he's extremely patient with my questions. For 5 months, I've been in constant pain, and after the procedure he recommended, I feel so much better. Thank you, Dr. Prendes. You are truly a blessing.

Reviewed on Jul 1, 2019

Dr.Prendes is a Saint. And your entire staff is excellent.

Reviewed on Jul 1, 2019

I have nominated Dr.,Prendes for Sainthood.

Reviewed on Jun 14, 2019

this was my second visit with dr. Brandon prendes. As with my first visit, he exemplifies concern, compassion, and a passion to help his patience. he as well as my other doctors and my family's doctors are world class caregivers! That is why we have been to the Cleveland clinic for thirteen years for our medical care!

Reviewed on Jun 6, 2019

Dr. Prendes is one of the best specialists I'm blessed to meet. I've been in pain and discomfort for several months, and he's thoroughness has helped me get to where I am right now. I'm confident that he will help me get back to my best health.

Reviewed on May 23, 2019

loved Dr. Prendes and the Dr who did biopsy. very kind and professional

Reviewed on May 20, 2019

Dr. Prendes is excellent in all above areas.

Reviewed on May 20, 2019

I couldn't have asked for a better provider then Dr. Prendes! He was caring, listened to all of my questions and concerns and explained everything in simple terms. He is a shining example of what a provider should be.

Reviewed on May 16, 2019

The staff and Dr Prendes are outstanding.

Reviewed on May 6, 2019

Exceptional. The professionalism, the friendliness, the "relatability" of Dr. Prendes and his team to my family and to me in my care was outstanding.

Reviewed on May 6, 2019

All my experiences was very professional. I would recommend Dr. Prendes to anyone.

Reviewed on Apr 29, 2019

Dr. Prendes, who was knowledgeable and understanding, addressed my concerns in a proficient manner.

Reviewed on Mar 5, 2019

Dr. Prendre is truly a quality physician and very thorough.

Reviewed on Feb 26, 2019

Dr. Prendes was excellent. would highly recommend him.

Reviewed on Feb 21, 2019

I had to wait an hour for the doctor visit!! my appointment was at 9:30 am and never saw me till 10:20 am

Reviewed on Feb 21, 2019

Everyone was amazing and compassionate. From Laura who checked me in at the desk, Britanny who checked me in at the exam room and Dr. Prendes himself. As an RN for almost 4 decades, I was extremely impressed.

Reviewed on Feb 21, 2019

I have already recommended Dr. Prendes to 2 other potential patients.

Reviewed on Feb 14, 2019

Dr. Prendas is awesome, very professional and a kind heart.God Bless him

Reviewed on Jan 22, 2019

Have always had a good experience when dealing with Cleveland Clinic and their Doctors. Dr. Prendes is the best!

Reviewed on Jan 18, 2019

Doctor was excellent

Reviewed on Jan 17, 2019

Dr. Prendes was amazingly patient, understanding, empathetic, and kind to my mother and her brood of overly inquisitive adult children. He made her feel as though she was just as important as any other patient. I would whole-heartedly recommend him to anyone.

Reviewed on Jan 11, 2019

Dr. Prendes is the best !

Reviewed on Jan 9, 2019

Dr Brandon Prendise is excellent.

Reviewed on Jan 9, 2019

Dr. Prendes takes time to answer any questions I may have and listens with care and compassion. He is an amazing Dr. and should teach classes to other medical professionals on how to treat patients.

Reviewed on Jan 7, 2019

Friendly, trustworthy, knowledgeable, makes great eye contact, answers questions, a physician who goes above and beyond!

Reviewed on Nov 1, 2018

Dr. Prendes was outstanding in his communication and follow up. I received a personal phone call from him when the biopsy report came in which was most appreciated!

Reviewed on Oct 8, 2018

As always, my latest clinic session with Dr. Prendes and his staff was very useful and enjoyable.

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