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Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Adult Airway Reconstruction
  • Airway Stenosis Treatment
  • Cancer Center
  • Endoscopic Skull Base Surgery
  • Endoscopic Zenker's Diverticulum Surgery
  • Facial Reanimation
  • Facial Reconstruction
  • Head and Neck Cancer Surgery
  • Head and Neck Cancer Treatment
  • Head and Neck Endocrine Surgery
  • Head and Neck Reconstructive Surgery
  • Laser Surgery
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Robotic Surgery
  • Salivary Gland Surgery
  • Sialoendoscopy
  • Tracheal Resection
  • Tracheostomy
  • Tracheostomy Care
  • Tracheotomy
  • Ultrasound-Guided Procedures
  • Vocal Cord Paralysis Treatment
View all 23 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult and Pediatric Facial Trauma
  • Airway Obstruction
  • Benign Maxillofacial Tumors
  • Benign Skull Base Tumors
  • Benign Tumors of the Head
  • Benign Tumors of the Neck
  • Carotid Body Tumor
  • Dysphagia
  • Esthesioneuroblastoma
  • Facial Trauma
  • Glomus Tumors
  • Glomus Vagale Tumors
  • Head and Neck Cancer
  • Head and Neck Masses
  • Head and Neck Paragangliomas
  • Head and Neck Trauma
  • Head and Neck Tumors
  • Hypopharyngeal Cancer
  • Laryngeal Cancer
  • Laryngeal Stenosis
  • Laryngeal Tracheal Reconstruction
  • Lip and Oral Cavity Cancer
  • Malignant Head and Neck Disease
  • Malignant Tumors of the Head
  • Melanoma
  • Minor Salivary Gland Cancer
  • Nasal Cavity Cancer
  • Nasopharyngeal Cancer
  • Neck Cancer
  • Oropharyngeal Cancer
  • Paraganglioma
  • Parathyroid Cancer
  • Parotid Cancer
  • Pediatric Head and Neck Cancer
  • Pituitary Tumors
  • Rare Cancer and Blood Disease Program
  • Salivary Gland Cancer
  • Salivary Gland Diseases
  • Salivary Gland Tumors
  • Sarcoma
  • Sinonasal Tumors
  • Skull Base Cancer
  • Subglottic Stenosis
  • Submandibular Gland Cancer
  • Thyroid Cancer
  • Thyroid Masses
  • Thyroid Nodule
  • Tracheal Stenosis
  • Tracheoesophageal Fistula
  • Vocal Cord Paralysis
  • Zenker's Diverticulum
View all 51 Specialties +


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About Brandon Prendes, M.D.

Brandon Prendes, MD, is a surgeon in the Cleveland Clinic's Head and Neck Institute and a Staff Member of both the Section of Head and Neck Surgery and the Section of Facial Plastic and Reconstructive Surgery. He is board-certified by the State of Ohio Medical Board and the American Board of Otolaryngology. His specialty interests include head and neck cancer surgery, microvascular reconstructive surgery, thyroid and parathyroid surgery, transoral robotic surgery, benign and malignant salivary tumors and diseases (including endoscopic removal of salivary gland stones), ultrasonography for diagnosis of head and neck tumors, sinonasal tumors, and skull base surgery.

Dr. Prendes' education includes a Bachelors of Science in Engineering, Summa Cum Laude, from the University of Michigan and a Medical Doctorate from the University of Pennsylvania School of Medicine. He completed a surgical internship and an Otolaryngology - Head and Neck Surgery Residency at the University of California San Francisco. He pursued further fellowship training in advanced head and neck cancer, endocrine, and microvascular reconstructive surgery at the Cleveland Clinic prior to joining the Head and Neck Institute as Professional Staff.

Dr. Prendes is a member of the American Academy of Otolaryngology - Head and Neck Surgery and of the American Head and Neck Society. He also serves as an educator teaching medical students, residents, and fellows. He has published a number of journal articles on topics ranging from the involvement of the human papilloma virus (HPV) in throat cancer to the endoscopic treatment of salivary gland diseases and has presented on these topics at national academic meetings.

Listen to Dr. Prendes on our Head and Neck Innovations podcast: Outcomes After Oral Cavity and Oropharyngeal Salvage Surgery

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Head & Neck Oncologic & Reconstructive Fellowship
Cleveland, OH USA

Residency - University of California-San Francisco
San Francisco, CA USA

Medical Education - University of Pennsylvania
Philadelphia, PA USA

Undergraduate - University of Michigan
Ann Arbor, MI USA


  • Otolaryngology

Specialty Interests

Robotic transoral surgery, airway stenosis, adult airway reconstruction, laryngeal and tracheal reconstruction, head and neck cancer, congenital and benign and malignant tumors of the head and neck, head and neck reconstructive surgery for cancer and for trauma, microvascular reconstructive surgery, head and neck endocrine (thyroid and parathyroid gland) surgery and malignant tumors, salivary gland tumors and cancer, skin cancer of the head and neck including melanoma, paranasal sinus tumors, skull base surgery, parapharyngeal space tumors, endoscopic treatment of salivary gland stones and diseases (sialendoscopy).

Awards & Honors

  • Western Section of the Triologic Society Vice President's Research Award
Research & Publications

Research & Publications

See publications for Brandon Prendes, M.D..

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/22/2023, Dr. Prendes has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

235 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.7
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

41 Patient Comments

Reviewed on Aug 17, 2023

Dr. Prendes is very laid back and an excellent listener. I didn't feel rushed. He answered my questions with knowledge, wisdom and understanding. I feel comfortable knowing that he will be doing my surgery.

Reviewed on Aug 17, 2023

All I have to say is that man changed my life for the better I can't even put into words what he has done for me I couldn't be anymore happier then I am thank you sooo much Dr Prendes

Reviewed on Aug 15, 2023

An excellent doctor

Reviewed on Jun 26, 2023

Dr Prendes came highly recommended and I will do the same. I have complete confidence in him.

Reviewed on Jun 22, 2023

Dr. Prendes was very accommodating and listened to my concerns.

Reviewed on Jun 22, 2023

Dr Prendes was excellent. Nice personality.

Reviewed on Jun 20, 2023

Super great doctor. Has a great heart, very nice man, an excellent human being

Reviewed on Jun 15, 2023

He seemed to understand my concerns and answer questions in a kind, caring manner. First visit. Like him a lot.

Reviewed on Jun 15, 2023

Dr. Prendes is an excellent physician & brilliant surgeon. He his very considerate, thoughtful & courteous. I am thankful that I have such a wonderful doctor.

Reviewed on Jun 8, 2023

Dr Prendes and staff are very professional and polite.

Reviewed on Jun 8, 2023

Dr. Prendes always takes his time and explains everything In detail and answers any questions we have.

Reviewed on May 18, 2023

One of the absolute best doctors I've ever had.

Reviewed on May 12, 2023

Dr. Prendes saw me on very short notice and I was very grateful for that.

Reviewed on May 12, 2023

The Surgical Guide binder is very helpful and Dr. Prendes was careful and clear in his explanation of the surgery and pain management.

Reviewed on May 12, 2023

Dr. Entered close to bc appointment time. He had good assistant s. Everyone was efficient and answered all my questions.

Reviewed on Apr 21, 2023

Dr. Prendes and Carly couldn't have been nicer.

Reviewed on Apr 20, 2023

Dr Prendes is an amazing doctor. I would and I have recommended him to family and friends. Doctors like him are what makes the Cleveland Clinic a number one world class health care facility. Our family is grateful to have found him.

Reviewed on Apr 4, 2023

Loved my Dr. He was the best! Ok

Reviewed on Mar 21, 2023

Dr. Prendes is great.

Reviewed on Mar 21, 2023

Dr Prendes has been top notch! Great from the beginning, now 3 years, very patience and nice

Reviewed on Mar 10, 2023

So very concerned and caring love this Doctor's care for me

Reviewed on Mar 7, 2023

Over all everything is fine Dr Prendes is who I am trusting my care to for a long on going problem. Which requires his skills and experience.

Reviewed on Mar 7, 2023

Dr Brandon L Prendens md is a great surgeon and great doctor he did my surgery properly and I appreciate him a lot he cares about his patients I trust him with my health he's a great man thank you sir really I appreciate you a lot

Reviewed on Feb 23, 2023

Dr Prendes is a amazing doctor will a amazing bedside manner

Reviewed on Feb 23, 2023

Great doctor. Would definitely recommend him to anyone

Reviewed on Feb 23, 2023

I would recommend Dr. Prendes and his staff to everyone.

Reviewed on Feb 23, 2023

Dr. Prendes and his staff of assistance's were very caring,helpful and excellent In administrating treatment. His explanations of what was happening in the procedure was professional.

Reviewed on Feb 17, 2023

I always recommend Dr Prendes to people I know who need care due to having tracheotomies. He has been one of the most kind, understanding care givers I've ever had. Having a trach is a very scary , traumatic experience, but Dr Prendes always made me feel comfortable and always reassured me that I would get better, which I did . I'm grateful for Dr Prendes and his staff for their excellent care.

Reviewed on Feb 10, 2023

Dr Prendes is extremely professional. His care has been nothing but educated and exceptional.

Reviewed on Feb 9, 2023

Dr prendes is a very caring doctor

Reviewed on Jan 12, 2023

Dr. Prendes is a great Dr. He is caring and kind and compassionate!! , always takes the time to talk with you and address any concerns I might have I always feel comfortable with him and most important I trust him with my care and so does my wife, there is a comfort when we know we are seeing him

Reviewed on Dec 22, 2022

Doctor Prendes is very knowledgeable Underdtsnding caring concerned and responsible

Reviewed on Dec 21, 2022

Dr.Prendes was very nice and caring,

Reviewed on Dec 20, 2022

Very caring doctor.

Reviewed on Dec 20, 2022

Dr. Prendes always takes time to listen to me (even tho I no longer speaks super clearly) about all my concerns and questions. He asks about my family, even remembers my son's names and what they are into.

Reviewed on Dec 9, 2022

Excellent experience! Doc and team were Great!

Reviewed on Nov 29, 2022

I respect Dr. Prendes.

Reviewed on Oct 31, 2022

Dr Prendes n his staff are wonderful

Reviewed on Oct 20, 2022

I thought this was a care survey. This doctor is the first doctor in Cleveland clinic that I had a truly positive experience with. It was refreshing and I am confident that he takes his patient's wellbeing seriously.

Reviewed on Oct 13, 2022

*Dr. Brandon Prendes is an awesome doctor! Truly amazing. And very patient with all my questions.

Reviewed on Sep 8, 2022

Brandon Prendes is a fantastic doctor. He always responds to my questions in a complete and timely manner and shows true compassion for my well being

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