Emergency icon Important Updates
Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Adult Airway Reconstruction
  • Airway Stenosis Treatment
  • Cancer Center
  • Endoscopic Skull Base Surgery
  • Endoscopic Zenker's Diverticulum Surgery
  • Facial Reanimation
  • Facial Reconstruction
  • Head and Neck Cancer Surgery
  • Head and Neck Cancer Treatment
  • Head and Neck Endocrine Surgery
  • Head and Neck Reconstructive Surgery
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Robotic Surgery
  • Salivary Gland Surgery
  • Sialoendoscopy
  • Tracheal Resection
  • Tracheostomy
  • Tracheostomy Care
  • Tracheotomy
  • Ultrasound-Guided Procedures
  • Vocal Cord Paralysis Treatment
View all 22 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult and Pediatric Facial Trauma
  • Airway Obstruction
  • Benign Maxillofacial Tumors
  • Benign Skull Base Tumors
  • Benign Tumors of the Head
  • Benign Tumors of the Neck
  • Carotid Body Tumor
  • Dysphagia
  • Esthesioneuroblastoma
  • Facial Trauma
  • Glomus Tumors
  • Glomus Vagale Tumors
  • Head and Neck Cancer
  • Head and Neck Masses
  • Head and Neck Paragangliomas
  • Head and Neck Trauma
  • Head and Neck Tumors
  • Hypopharyngeal Cancer
  • Laryngeal Cancer
  • Laryngeal Stenosis
  • Laryngeal Tracheal Reconstruction
  • Lip and Oral Cavity Cancer
  • Malignant Tumors of the Head
  • Melanoma
  • Minor Salivary Gland Cancer
  • Nasal Cavity Cancer
  • Nasopharyngeal Cancer
  • Neck Cancer
  • Oropharyngeal Cancer
  • Paraganglioma
  • Parathyroid Cancer
  • Parotid Cancer
  • Pediatric Head and Neck Cancer
  • Pituitary Tumors
  • Rare Cancer and Blood Disease Program
  • Salivary Gland Cancer
  • Salivary Gland Diseases
  • Salivary Gland Tumors
  • Sarcoma
  • Sinonasal Tumors
  • Skull Base Cancer
  • Subglottic Stenosis
  • Submandibular Gland Cancer
  • Thyroid Cancer
  • Thyroid Masses
  • Thyroid Nodule
  • Tracheal Stenosis
  • Tracheoesophageal Fistula
  • Vocal Cord Paralysis
  • Zenker's Diverticulum
View all 50 Specialties +


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Brandon Prendes, MD

Brandon Prendes, MD, is a surgeon in the Cleveland Clinic's Head and Neck Institute and a Staff Member of both the Section of Head and Neck Surgery and the Section of Facial Plastic and Reconstructive Surgery. He is board-certified by the State of Ohio Medical Board and the American Board of Otolaryngology. His specialty interests include head and neck cancer surgery, microvascular reconstructive surgery, thyroid and parathyroid surgery, transoral robotic surgery, benign and malignant salivary tumors and diseases (including endoscopic removal of salivary gland stones), ultrasonography for diagnosis of head and neck tumors, sinonasal tumors, and skull base surgery.

Dr. Prendes' education includes a Bachelors of Science in Engineering, Summa Cum Laude, from the University of Michigan and a Medical Doctorate from the University of Pennsylvania School of Medicine. He completed a surgical internship and an Otolaryngology - Head and Neck Surgery Residency at the University of California San Francisco. He pursued further fellowship training in advanced head and neck cancer, endocrine, and microvascular reconstructive surgery at the Cleveland Clinic prior to joining the Head and Neck Institute as Professional Staff.

Dr. Prendes is a member of the American Academy of Otolaryngology - Head and Neck Surgery and of the American Head and Neck Society. He also serves as an educator teaching medical students, residents, and fellows. He has published a number of journal articles on topics ranging from the involvement of the human papilloma virus (HPV) in throat cancer to the endoscopic treatment of salivary gland diseases and has presented on these topics at national academic meetings.

Listen to Dr. Prendes on our Head and Neck Innovations podcast: Outcomes After Oral Cavity and Oropharyngeal Salvage Surgery

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Head & Neck Oncologic & Reconstructive Fellowship
Cleveland, OH

Residency - University of California-San Francisco
San Francisco, CA

Medical Education - University of Pennsylvania
Philadelphia, PA

Undergraduate - University of Michigan
Ann Arbor, MI


  • Otolaryngology - Head and Neck Surgery

Specialty Interests

Robotic transoral surgery, airway stenosis, adult airway reconstruction, laryngeal and tracheal reconstruction, head and neck cancer, congenital and benign and malignant tumors of the head and neck, head and neck reconstructive surgery for cancer and for trauma, microvascular reconstructive surgery, head and neck endocrine (thyroid and parathyroid gland) surgery and malignant tumors, salivary gland tumors and cancer, skin cancer of the head and neck including melanoma, paranasal sinus tumors, skull base surgery, parapharyngeal space tumors, endoscopic treatment of salivary gland stones and diseases (sialendoscopy).

Awards & Honors

  • Western Section of the Triologic Society Vice President's Research Award
Research & Publications

Research & Publications

See publications for Brandon Prendes, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/1/2024, Dr. Prendes has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

221 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.7
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

37 Patient Comments

Reviewed on May 9, 2024

Dr Prendes is a wonderful surgeon

Reviewed on Apr 30, 2024

Excellent doctor. Very friendly and courteous.

Reviewed on Apr 25, 2024

Dr Brandon Prendes was great. Very caring.

Reviewed on Apr 23, 2024

Great team across the board. That said, I think Dr Prendes is an exceptional physician. Have had excellent experiences with virtually every doctor/nurse at the Clinic, however, Dr Prendes is especially good. He certainly has excellent skills but was also able to really engage with mecame across as being genuinely interested in me as well as the lump on food of my mouth (eg asked if I was retired). Very authenticprofessional as well as likable, warm, caring.

Reviewed on Apr 11, 2024

I just love Dr Prendes and his staff.

Reviewed on Mar 28, 2024

Dr Prendes is the best. Kind, gentle, expert, thorough. Couldn't ask for a better doctor.

Reviewed on Mar 26, 2024

Doctor Prendes is the best!

Reviewed on Mar 21, 2024

Dr Prendes wanted to see me for a 3 week follow-up on my surgery. Scheduling could not find a date anywhere near that timeframe. I messaged Dr Prendes office and within 12 hours they arranged the required follow up. Great staff/doctor!

Reviewed on Mar 19, 2024

Probably our favorite doctor!

Reviewed on Mar 19, 2024

Dr. Prendes is perfect. He responds to my endless questions and is always patient with me. He takes his time cleaning out my nose. Patient when I need a need a minute before he continues. I could not ask for a better surgeon/ doctor. Everyone comments on how good my face looks post surgery.

Reviewed on Mar 19, 2024

Dr. P is great. 100% confidence in him. Would highly recommend him.

Reviewed on Feb 22, 2024

Best doctor ever. Good bedside manner very personable. Would recommend him to everyone.

Reviewed on Feb 9, 2024

I have seeing Dr. Prendes for over 4 years. He is the best...always very compassionate and caring. Keeps me informed on what's going on with my treatments and outcomes, etc. I would highly recommend him to anyone.

Reviewed on Jan 30, 2024

Dr Prendez is at the top of his game. Perfect surgeon

Reviewed on Jan 29, 2024

Such a great experience with Dr.

Reviewed on Jan 29, 2024

Can't express enough have wonderful Dr Prendes is. I will highly recommend him

Reviewed on Dec 14, 2023

Dr.Prendes is amazing always takes his time and answers any questions or concerns my wife and I may have and advises us on next appointment.

Reviewed on Dec 14, 2023

I will definitely recommend the clinic and Dr.Prendes. To anyone I know and as a matter of fact I already have.

Reviewed on Dec 8, 2023

Dr.Prendes is a fantastic Dr. He is kind and caring and always makes us feel comfortable

Reviewed on Nov 22, 2023

Best Doctor I have ever encountered. My entire family are surgeons and Dr. Brandon cares, is professional, and is amazing at his craft.

Reviewed on Nov 21, 2023

I just love Dr Prendes and all his staff.

Reviewed on Oct 26, 2023

Dr Prendes is the absolute best. Caring, empathetic and very knowledgeable.

Reviewed on Oct 17, 2023

Amazing doctor and staff

Reviewed on Oct 17, 2023

Dr Brandon Prendes exceeds my expectations. He is caring and thorough. I really appreciate him as my doctor.

Reviewed on Sep 19, 2023

Dr Prendes is extremely professional and courteous. He is profoundly interested in my well being and treatment of my illness. His intelligence is immeasurable. I truly appreciate these attributes and would recommend him to anyone with head and neck disease. He's simply fabulous!

Reviewed on Sep 8, 2023

Dr Prendes listened to my questions with genuine concern, and he answered them thoughtfully in layman's language that I could understand. He was also friendly, and spoke of my situation in a very calming manner with concise options for future treatment. Lastly, Dr Prendes took as much time as I needed; I was not rushed or shown any signs of impatience.

Reviewed on Aug 17, 2023

Dr. Prendes is very laid back and an excellent listener. I didn't feel rushed. He answered my questions with knowledge, wisdom and understanding. I feel comfortable knowing that he will be doing my surgery.

Reviewed on Aug 17, 2023

All I have to say is that man changed my life for the better I can't even put into words what he has done for me I couldn't be anymore happier then I am thank you sooo much Dr Prendes

Reviewed on Aug 15, 2023

An excellent doctor

Reviewed on Jun 26, 2023

Dr Prendes came highly recommended and I will do the same. I have complete confidence in him.

Reviewed on Jun 22, 2023

Dr. Prendes was very accommodating and listened to my concerns.

Reviewed on Jun 22, 2023

Dr Prendes was excellent. Nice personality.

Reviewed on Jun 20, 2023

Super great doctor. Has a great heart, very nice man, an excellent human being

Reviewed on Jun 15, 2023

He seemed to understand my concerns and answer questions in a kind, caring manner. First visit. Like him a lot.

Reviewed on Jun 15, 2023

Dr. Prendes is an excellent physician & brilliant surgeon. He his very considerate, thoughtful & courteous. I am thankful that I have such a wonderful doctor.

Reviewed on Jun 8, 2023

Dr Prendes and staff are very professional and polite.

Reviewed on Jun 8, 2023

Dr. Prendes always takes his time and explains everything In detail and answers any questions we have.

Back to Top