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Department Head and Neck Institute
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Specialties & Treatments

Treatment & Services

  • Airway Stenosis Treatment
  • Cancer Center
  • Endoscopic Pituitary Surgery
  • Endoscopic Skull Base Surgery
  • Endoscopic Zenker's Diverticulum Surgery
  • Facial Reanimation
  • Head and Neck Cancer Surgery
  • Head And Neck Cancer Treatment
  • Head and Neck Endocrine Surgery
  • Head and neck reconstructive surgery
  • Laser Surgery
  • Microvascular Reconstruction
  • Microvascular Surgery
  • Reconstructive Head And Neck Surgery
  • Reconstructive Surgery of the Face
  • Robotic Surgery
  • Salivary Gland Surgery
  • Sialoendoscopy
  • Tracheal Resection
  • Tracheostomy
  • Tracheostomy Care
  • Tracheotomy
  • Transsphenoidal Pituitary Surgery
  • Ultrasound-guided Procedures
  • Vocal Cord Paralysis Treatment
View all 25 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult Airway Reconstruction
  • Adult and Pediatric Facial Trauma
  • Airway Obstruction and Tracheotomy
  • Benign Maxillofacial Tumors
  • Benign Skull Base Tumors
  • Benign Tumors Of The Head
  • Benign Tumors Of The Neck
  • Carotid Body Tumor
  • Dysphagia
  • Esthesioneuroblastoma
  • Facial Trauma
  • Glomus Tumors
  • Glomus Vagale Tumors
  • Head and Neck Cancer
  • Head and Neck Masses
  • Head and Neck Paragangliomas
  • Head and Neck Trauma
  • Head And Neck Tumors
  • Hypopharyngeal Cancer
  • Laryngeal Cancer
  • Laryngeal Stenosis
  • Laryngeal Tracheal Reconstruction
  • Lip and Oral Cavity Cancer
  • Malignant Head and Neck Disease
  • Malignant Tumors Of The Head
  • Malignant Tumors Of The Neck
  • Melanoma
  • Minor Salivary Gland Cancer
  • Nasal Cavity Cancer
  • Nasopharyngeal Cancer
  • Oropharyngeal Cancer
  • Paraganglioma
  • Parathyroid Cancer
  • Parotid Cancer
  • Pediatric Head And Neck Cancer
  • Pituitary Tumors
  • Rare Cancer and Blood Disease Program
  • Salivary Gland Cancer
  • Salivary Gland Diseases
  • Salivary Gland Neoplasms
  • Sarcoma
  • Sinonasal Tumors
  • Skull Base Cancer
  • Subglottic Stenosis
  • Submandibular Gland Cancer
  • Thyroid Cancer
  • Thyroid Masses
  • Thyroid Nodule
  • Tracheal Stenosis
  • Tracheoesophageal Fistula
  • Vocal Cord Paralysis
  • Zenker's Diverticulum
View all 52 Specialties +


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About Brandon Prendes, M.D.

Brandon Prendes, MD, is a surgeon in the Cleveland Clinic's Head and Neck Institute and a Staff Member of both the Section of Head and Neck Surgery and the Section of Facial Plastic and Reconstructive Surgery. He is board-certified by the State of Ohio Medical Board and the American Board of Otolaryngology. His specialty interests include head and neck cancer surgery, microvascular reconstructive surgery, thyroid and parathyroid surgery, transoral robotic surgery, benign and malignant salivary tumors and diseases (including endoscopic removal of salivary gland stones), ultrasonography for diagnosis of head and neck tumors, sinonasal tumors, and skull base surgery.

Dr. Prendes' education includes a Bachelors of Science in Engineering, Summa Cum Laude, from the University of Michigan and a Medical Doctorate from the University of Pennsylvania School of Medicine. He completed a surgical internship and an Otolaryngology - Head and Neck Surgery Residency at the University of California San Francisco. He pursued further fellowship training in advanced head and neck cancer, endocrine, and microvascular reconstructive surgery at the Cleveland Clinic prior to joining the Head and Neck Institute as Professional Staff.

Dr. Prendes is a member of the American Academy of Otolaryngology - Head and Neck Surgery and of the American Head and Neck Society. He also serves as an educator teaching medical students, residents, and fellows. He has published a number of journal articles on topics ranging from the involvement of the human papilloma virus (HPV) in throat cancer to the endoscopic treatment of salivary gland diseases and has presented on these topics at national academic meetings.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Head & Neck Oncologic & Reconstructive Fellowship
Cleveland, OH USA

Residency - University of California-San Francisco
San Francisco, CA USA

Medical Education - University of Pennsylvania
Philadelphia, PA USA

Undergraduate - University of Michigan
Ann Arbor, MI USA


  • Otolaryngology

Specialty Interests

Robotic transoral surgery, airway stenosis, adult airway reconstruction, laryngeal and tracheal reconstruction, head and neck cancer, congenital and benign and malignant tumors of the head and neck, head and neck reconstructive surgery for cancer and for trauma, microvascular reconstructive surgery, head and neck endocrine (thyroid and parathyroid gland) surgery and malignant tumors, salivary gland tumors and cancer, skin cancer of the head and neck including melanoma, paranasal sinus tumors, skull base surgery, parapharyngeal space tumors, endoscopic treatment of salivary gland stones and diseases (sialendoscopy).

Awards & Honors

  • Western Section of the Triologic Society Vice President's Research Award
Research & Publications

Research & Publications

See publications for Brandon Prendes, M.D..

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 4/8/2021, Dr. Prendes has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

163 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.8
Listens 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

36 Patient Comments

Reviewed on Sep 16, 2021

Dr Pendes and his staff (Brittney and his notetaker) are the dream team. Extremely caring and professional.

Reviewed on Sep 16, 2021

I would highly recommend Dr Prendes. He is highly knowledgeable and caring.

Reviewed on Sep 16, 2021

Bethany was a great advocate from Dr. Prendes' office

Reviewed on Sep 8, 2021

I love Dr Prendes he is very goodThe staff needs to communicate with the patients if he going to be delayed

Reviewed on Aug 23, 2021

Dr. Prendes is so caring and listens to any concerns. He is truly a lifesaver.

Reviewed on Aug 11, 2021

I always get excellent care in every way from Dr. Prendes. Today was no exception.

Reviewed on Aug 11, 2021

Dr. Prendes was very kind and courteous. He explained that he may not be the type of provider that I need, but did give me suggestions on what type of doctor to see next. He also ordered a test to check for any condition he may be able to help resolve. That made me feel confident that he was doing the best he could to rule out anything he could treat for me.

Reviewed on Jul 20, 2021

Dr. Prendes and his staff and the clinic staff in general were all excellent and easy to deal with. Enjoyed my latest medical checkup.

Reviewed on Jul 20, 2021

I appreciate the care I reduce from Dr. Prendes.

Reviewed on Jul 20, 2021

Dr. Prendes is an excellent physician. He has treated me as an adult! He communicated my status very effectively to me and my wife. He has been professional, warm, friendly and has shared a sense of humor with me as I have with him. I was very impressed from the beginning of our "event" with him. I rate him extremely high as a person, a professional, and of a care giver.

Reviewed on Jul 15, 2021

Dr. Prendes is super nice and very caring.

Reviewed on Jun 14, 2021

Dr. Prendes is great. He's been looking after me and my cancer for almost 10 years.

Reviewed on Jun 14, 2021

I love this doctor. He found out I needed a traceostomy when I was in the hospital for nearly 3 months and he and his team did my trach. Seeing him for followup and closing of trach stoma.

Reviewed on Jun 14, 2021

Dr Prendes and his staff were amazing.

Reviewed on Jun 10, 2021

saw 3 doctors and all 3 were super to me

Reviewed on Jun 10, 2021

Dr. Prendes is excellent! An knowledgeable professional and a very caring person.

Reviewed on Jun 7, 2021

Dr. Prendes was very patient and took the time to answer any questions. The whole experience set me at ease.

Reviewed on May 25, 2021

my team of doctors know their stuff !

Reviewed on May 18, 2021

Dr. Prendes is the best! He's caring and so easy to talk to. He answers all questions and concerns. He literally saved a life.

Reviewed on May 7, 2021

We haven't received many of the bills at all yet so I rated N/A. Overall I'm deeply grateful to Cleve. Clinic and *Dr. Prendes, *Brandon Prendes.

Reviewed on May 7, 2021

*Dr. Prendes and his team was excellent. I'm very grateful to *Dr. Prendes; also to the endocrinology rounding team.

Reviewed on Apr 26, 2021

Dr. Prendes is an amazing doctor. I'm so thankful to have him!!

Reviewed on Apr 15, 2021

Felt very comfortable with Dr. Prendes.

Reviewed on Apr 14, 2021

I trust my doctor

Reviewed on Apr 14, 2021

Dr Prendes is an excellent physician and his support staff/nurses are very professional. Everyone is so kind and helpful. I feel Dr Prendes truly listens to my concerns and takes his time in finding answers or to give me information.

Reviewed on Apr 14, 2021

I would highly recommend Dr Prendes and the Cleveland Clinic

Reviewed on Apr 12, 2021

Dr Prendes was friendly, confident and knowledgeable- great combination.

Reviewed on Mar 11, 2021

overall great experience..appt availability is more of work load on Dr Prendes and I understand that there are limited time slots.

Reviewed on Mar 8, 2021

love the care provider

Reviewed on Feb 18, 2021

I really like Dr. Prendez. He takes his time with you and addresses your concerns.

Reviewed on Feb 10, 2021

The only downfall is the physician can't physically grab your tongue and look at it other than that it save me a 4 1/2 hour drive one way

Reviewed on Jan 8, 2021

Dr. Prendes is warm and pleasant. Very patient-oriented. He listens, which is the most important thing a doctor can do.

Reviewed on Jan 5, 2021

Dr. Prendes is one of the best doctors I have ever had.

Reviewed on Dec 9, 2020

Dr Prendes is a wonderful doctor who always takes time to answer my questions and explain things to me. He's the greatest!!!

Reviewed on Nov 30, 2020

all the care provider were excellent thanks

Reviewed on Oct 22, 2020

it was a very good experience. Dr. Prendes was very kind and easy to speak with.

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