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Department Orthopaedic Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Locations
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus

Appointment:
216.444.2606
Desk:
216.444.4603
Fax:
216.445.1638

Additional Locations

Specialties & Treatments

Treatment & Services

  • 2nd Opinion Evaluations
  • Arthritis Surgery
  • Arthroplasty
  • Bone Grafting
  • Bone Tumor Surgery
  • Cancer
  • Cancer Center
  • Complex Primary Hip Arthroplasty
  • Complex Primary Knee Arthroplasty
  • Hip & Knee Surgery
  • Hip Replacement
  • Joint Preserving Hip Surgery
  • Joint Reconstruction
  • Joint Replacement
  • Joint Replacement Of The Knee
  • Knee Arthroplasty
  • Knee Revision
  • Knee Surgery
  • Musculoskeletal Oncology
  • Orthopaedic Surgery
  • Orthopaedics
  • Primary And Revision Joint Replacements
  • Primary And Revision Total Hip Arthroplasty
  • Primary And Revision Total Knee Arthroplasty
  • Reconstructive Surgery
  • Reconstructive Surgery Of The Hip
  • Reconstructive Surgery Of The Knee
  • Revision Hip Arthroplasty
  • Revision Hip Joint Replacement
  • Revision Joint Replacement
  • Revision Knee Arthroplasty
  • Revision Knee Joint Replacement
  • Revision Surgery
  • Revision Total Hip Replacement
  • Revision Total Knee Replacement
  • Robotic Assisted Hip Replacement
  • Robotic Assisted Knee Replacement
  • Robotic Assisted Partial Knee Replacement
  • Sarcoma oncologists
  • Sarcoma surgery
  • Second Opinion
  • Soft Tissue (Sarcoma)
  • Soft Tissue Tumor Surgery
  • Surgical Treatment Of Arthritis Of The Hips And Knees
  • Total Hip And Total Knee Replacement
  • Total Joint Replacement
View all 46 Treatment & Services +

Specialty in Diseases & Conditions

  • Aneurysmal Bone Cyst
  • Arthritic Knee Problems
  • Arthritis
  • Arthritis Of The Hip
  • Arthritis Of The Knee
  • Avascular Necrosis
  • Avascular Necrosis Of The Hip
  • Avascular Necrosis Of The Knee
  • Benign Bone Tumors
  • Bone and Soft Tissue Tumors
  • Bone Cancer
  • Bone Tumors
  • Epithelioid Hemangioendothelioma (EHE)
  • Fractures
  • Giant Cell Tumor of Bone
  • Hip Replacement
  • Malignant Bone Tumors.
  • Malignant Peripheral Nerve Sheath Tumors
  • Osteonecrosis
  • Osteosarcoma
  • Pediatric Rare Cancer and Blood Disease Program
  • Pediatric Soft Tissue Sarcoma
  • Pigmented Villonodular Synovitis
  • Rare Cancer and Blood Disease Program
  • Sarcoma
  • Soft Tissue Sarcoma
  • Soft Tissue Tumor Pathology
View all 27 Specialties +
Insurance

Insurance

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Biography

About Nathan Mesko, MD

Nathan W. Mesko, MD is the Section Head of Orthopaedic Oncology and Trauma, and holds his appointment in the Orthopaedic and Rheumatologic Institute at Cleveland Clinic.  In addition, he is co-director of the Sarcoma Center in the Taussig Cancer Institute, and holds an Assistant Professorship at the Cleveland Clinic Lerner College of Medicine

After completing his college education at Wheaton College in Wheaton, Illinois, Dr. Mesko attended Loyola School of Medicine, where he was named to the Alpha Omega Alpha honor society.  He continued his residency training in orthopaedic surgery at Cleveland Clinic, followed by the pursuit of an orthopaedic oncology fellowship at Vanderbilt University (NasHVTIlle, TN).  Here, he received extensive training in benign and malignant bone and soft tissue lesions, metastatic bone and soft tissue cancer, bone and soft tissue sarcoma excision and reconstruction techniques, and complex total hip and total knee primary and revision arthroplasty.  After completing his training in NasHVTIlle, Dr. Mesko was the recipient of the Hatcher Pathology Fellowship from the Musculoskeletal Tumor Society, where he utilized this scholarship to visit various high volume sarcoma centers around the world. These efforts were intended to build further collaboration in the world of clinical and basic science outcome research between sarcoma institutions around the world, as well as to be immersed in various unique technologies.  After returning from England, Dr. Mesko joined the faculty of Cleveland Clinic in 2014.

Dr. Mesko is certified in orthopaedic surgery by the American Board of Orthopaedic Surgery.  He specializes in bone & soft tissue sarcoma diagnosis and treatment. In addition, he also specializes in the treatment of metastatic disease, as well as osteoarthritis and avascular necrosis requiring total joint arthroplasty, including hip resurfacing procedure.  His practice also encompasses total joint revision surgery.

Dr. Mesko’s research interests include clinical outcomes with bone and soft tissue sarcoma treatments, as well as working to improve educational efforts to increase sarcoma awareness.  He is part of a national team that has worked on creating a national sarcoma registry, in an effort to improve functional and cancer outcomes in this rare malignancy.  He has been active in recruiting collaborative projects from around the world to Cleveland Clinic, in an effort to make sure that patients at Cleveland Clinic are part of the latest advances in oncology care effecting the musculoskeletal system.

Outside the hospital, Dr. Mesko and his wife, raise 2 daughters and a Rhodesian ridgeback.  In addition, he enjoys spending time in regions of the world such as Africa and Central America, helping to teach and provide orthopaedic care to areas where appropriate musculoskeletal care is lacking.  Most recently, has enjoyed being a part of Hospital Shalom, a mission hospital in Flores, Guatemala.  He enjoys triathlons, downhill skiing, and water skiing as hobbies.

Education & Professional Highlights

Education & Professional Highlights

Appointed
2014

Education & Fellowships

Fellowship - Vanderbilt University Medical Center
Musculoskeletal Oncology
Nashville, TN USA
2014

Residency - Cleveland Clinic
Orthopaedic Surgery
Cleveland, OH USA
2013

Medical Education - Loyola University Stritch School of Medicine
Chicago, IL USA
2008

Undergraduate - Wheaton College
Wheaton, IL USA
2004

Certifications

  • Orthopaedic Surgery
Research & Publications

Research & Publications

See publications for Nathan Mesko, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/3/2022, Dr. Mesko has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Mesko receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • Onkos Surgical, Inc.
  • Stryker Corporation

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

163 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.7
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

22 Patient Comments

Reviewed on Dec 15, 2022

Dr. Mesko has been the best doctor overall I've ever worked with

Reviewed on Nov 8, 2022

Dr. Mesko is always so easy to talk to, answer questions. So happy to have him as my surgeon.

Reviewed on Nov 4, 2022

My level of respect increases to the degree my doctor listens to me and acknowledges my perspective.

Reviewed on Nov 4, 2022

The responsiveness of Dr. Mesko's entire staff is most impressive to me. My concerns or issues were promptly addressed each time I needed assistance. Since my location is not in Ohio, this was important to me.

Reviewed on Nov 1, 2022

Dr. Mesko has always been very respectful and informative about my procedures

Reviewed on Oct 25, 2022

Dr. Mesco did an excellent job. I'm very thankful that I had him as my doctor

Reviewed on Sep 28, 2022

Dr Mesko is the best!! I wouldn't go anywhere else

Reviewed on Sep 6, 2022

The doctor, his nurse and staff were extraordinary in their expertise and attentiveness to my questions and concerns.

Reviewed on Sep 6, 2022

I have already recommended this doctor and the Cleveland Clinic to others experiencing my same health condition.

Reviewed on Jul 29, 2022

Dr Mesko is amazing and I am very fortunate to have found him.

Reviewed on Jul 29, 2022

Dr Mesko is always kind and compassionate and answers all of our questions.

Reviewed on Jul 26, 2022

Great experience. Dr. Mesko, and his staff explained everything to me, and answered all my questions. When I emailed them post surgery, I received an answer promptly.

Reviewed on Jul 20, 2022

I was very favorably impressed with my entire experience at Cleveland Clinic. Doctor Mesko is great.

Reviewed on Jul 19, 2022

Dr. Mesko and his staff best group I've had with an illness

Reviewed on May 20, 2022

Dr Mesko is very professional and was the best. I would recommend him for surgery to anyone. Loved his bed side manner and informed me to what was happening and doing. I'll call him for my next surgery if I need any done.

Reviewed on May 17, 2022

Dr. Mesko, his Residents, and his nurse were all excellent!

Reviewed on May 6, 2022

Saw Dr Mesko med student first then Dr Mesko Both about equal in time no complaints

Reviewed on May 5, 2022

*Dr. Mesko and his residents were excellent! My hospitalist, *Dr. Mayock was outstanding!

Reviewed on May 3, 2022

De. Mesko and his PA asked questions and listened. Inquired about how life had been since the surgery 2 years ago.

Reviewed on Apr 26, 2022

Every follow up visit to Dr Mesko was very detailed responses, he is an excellent surgeon!

Reviewed on Mar 18, 2022

Dr Mesko and his associate treated me very well.

Reviewed on Mar 1, 2022

Dr. Mesko diagnosed and fixed a problem that others had failed to correctly identify. I am moving better than any time in the last three years and am pain free. He is an excellent doctor. Also thanks to my main Dr. Cartabuke for the recommendation.

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