Cancer Advances
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Featured Episode
Advances in the Management of Metastatic Bone Disease
Orthopedic Oncologist at Cleveland Clinic in Florida, Jorge Manrique-Succar, MD, returns to the Cancer Advances Podcast to share the latest advances in treating metastatic bone disease. Listen as Dr. Manrique talks about early intervention, advanced surgical techniques, and multidisciplinary collaboration are improving outcomes for cancer patients with skeletal-related complications.
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August 28, 2025
Breathing New Life Into Cancer Treatment: Inhaled KB707
Wen Wee Ma, MBBS, Enterprise Vice Chair for Research and Director of the Novel Cancer Therapeutics Center, joins the Cancer Advances Podcast to discuss a phase 1 trial of KB707 presented at ASCO 2025. This innovative therapy delivers IL-2 and IL-12 directly to the lungs through inhalation, aiming to minimize side effects and improve outcomes for patients with lung tumors. Dr. Ma shares early trial results and what they could mean for the future of cancer treatment.
Play NowAugust 21, 2025
Advancing Breast Cancer Care: Targeted Therapies, Sequencing, and Personalized Medicine
Kelley Kozma, DO, MS, Medical Director for Oncology at Cleveland Clinic Martin Health in Florida, to discuss how targeted therapies, next generation sequencing, and personalized medicine are transforming breast cancer care. Listen as Dr. Kozma shares how innovations like HER2-low targeting, liquid biopsy, and circulating tumor DNA are helping clinicians tailor treatments and improve outcomes.
Play NowAugust 14, 2025
Management of Clinically Node-Negative Salivary Gland Cancer
Brian Burkey, MD, MEd, Interim Director of the Scully Walsh Cancer Center and Division Chair of Otolaryngology Head and Neck Surgery at Cleveland Clinic in Florida, joins the Cancer Advances Podcast to talk about management strategies for clinically node-negative salivary gland cancer. Listen as Dr. Burkey highlights findings from an outcomes study and share strategies to better identify high-risk patients who may benefit from more aggressive treatment.
Play NowAugust 7, 2025
Reviving PALA: A New Role in Cancer Immunotherapy
George Stark, PhD, and Christine McDonald, PhD, from Cleveland Clinic's Lerner Research Institute, join the Cancer Advances Podcast to discuss the development of PALA as a novel immunostimulatory agent in oncology. Listen as they highlight promising preclinical data across multiple tumor types, potential for combination therapies and plans for clinical translation, including topical use for skin cancer.
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