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Department Orthopaedic Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Both Adults and Children & Adolescents
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Arthritis Surgery
  • Benign Soft Tissue Tumor Surgery
  • Bone Tumor Surgery
  • Cancer Center
  • Complex Primary Hip Arthroplasty
  • Fracture Care
  • Hip Replacement
  • Joint Injections
  • Joint Reconstruction
  • Joint Replacement
  • Knee Reconstructive Surgery
  • Knee Replacement
  • Musculoskeletal Oncology
  • Orthopaedic Pathology
  • Orthopaedic Surgery
  • Orthopaedics
  • Partial Knee Replacement
  • Primary Total Hip Arthroplasty
  • Reconstructive Surgery of the Hip
  • Revision Total Hip Replacement
  • Revision Total Knee Arthroplasty
  • Robotic Assisted Hip Replacement
  • Robotic Assisted Knee Replacement
  • Robotic Assisted Partial Knee Replacement
  • Sarcoma Oncologists
  • Sarcoma Surgery
  • Soft Tissue Tumor Pathology
  • Soft Tissue Tumor Surgery
  • Steroid Injections
  • Surgical Treatment of Arthritis of the Hip
  • Surgical Treatment of Arthritis of the Knee
  • Surgical Treatment of Metastatic Bone Disease
  • Total Hip Replacement
  • Total Knee Replacement
View all 34 Treatment & Services +

Specialty in Diseases & Conditions

  • Aneurysmal Bone Cyst
  • Arthritis
  • Arthritis of the Hip
  • Arthritis of the Knee
  • Avascular Necrosis
  • Avascular Necrosis of the Hip
  • Avascular Necrosis of the Knee
  • Benign Bone Tumors
  • Bone Cancer
  • Bone Disorders
  • Bone Tumors
  • Cancer
  • Epithelioid Hemangioendothelioma (EHE)
  • Foot Benign Tumors
  • Giant Cell Tumor of Bone
  • Hip Disorders
  • Hip Fracture
  • Knee Joint Disorders
  • Knee Problems
  • Malignant Peripheral Nerve Sheath Tumors
  • Musculoskeletal Disorders
  • Musculoskeletal Impairments
  • Musculoskeletal Pain
  • Osteoarthritis
  • Osteoarthritis of the Hips in the Elderly
  • Osteoarthritis of the Knees in the Elderly
  • Osteoporosis
  • Osteosarcoma
  • Pediatric Rare Cancer and Blood Disease Program
  • Pediatric Soft Tissue Sarcoma
  • Pigmented Villonodular Synovitis
  • Rare Cancer and Blood Disease Program
  • Sarcoma
  • Soft Tissue Sarcoma
View all 34 Specialties +


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About Lukas Nystrom, MD

Lukas Nystrom, MD, is a staff physician in the Department of Orthopaedic Surgery at Cleveland Clinic.  He completed his residency in orthopaedic surgery at the University of Iowa, and a fellowship in musculoskeletal oncology at the University of Florida. He specializes in the surgical treatment of musculoskeletal tumors.

In medical school Dr. Nystrom was to the Alpha Omega Alpha Honor Society, he is a fellow of the American Academy of Orthopaedic Surgeons, an Emerging Leader member of the American Orthopaedic Association and a full member of the Orthopaedic Research Society, Musculoskeletal Tumor Society and International Society of Limb Salvage.

Dr. Nystrom is interested in advanced techniques in limb-sparing surgery for musculoskeletal tumors, as well as in complex hip and knee replacement surgery. He has published over 20 peer-reviewed articles, numerous book chapters and has made many national and international presentations on topics related to orthopaedic oncology.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - University of Florida College of Medicine
Orthopedic Oncology
Gainesville, FL USA

Residency - University of Iowa
Orthopedic Surgery
Iowa City, IA USA

Medical Education - University of Minnesota
Minneapolis, MN USA

Undergraduate - Saint Olaf College
Northfield, MN USA


  • Orthopaedic Surgery
Research & Publications

Research & Publications

See publications for Lukas Nystrom, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 6/9/2023, Dr. Nystrom has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Nystrom receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Onkos Surgical, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

221 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.7
Courtesy, Respect & Concern 4.9
Time Spent with Patient 5
Patient Rating of Doctor 4.9

37 Patient Comments

Reviewed on Dec 15, 2023

If I were to give a rating for Dr Nystrom, It would be EXCELLENT! From the very beginning of my journey, he has Informed me of all aspects of the surgeries and what to expect after. I was most appreciative of his candor as I wanted to know the facts, nothing sugar coated. Now, I am cancer free and making great strides towards my new normal.

Reviewed on Dec 7, 2023

Dr. Luke Nystrom is outstanding, one of the best I've ever worked with

Reviewed on Dec 5, 2023

Dr Nystrom truly listens and cares. We develop a plan of care together that he makes sure I am comfortable with. He is thorough in his explanations. He is an amazing doctor! So appreciative of him!

Reviewed on Nov 21, 2023

Dr. Nystrom is a true professional

Reviewed on Nov 17, 2023

Dr. Nystrom is an amazing provider!

Reviewed on Nov 17, 2023

Dr. Nystrom and his team are always great to see. There professionalism,knowledge and kindness are unprecedented

Reviewed on Nov 16, 2023

Dr Nystrom was very caring. He remembered me from long ago. He was so compassionate regarding my condition.

Reviewed on Oct 17, 2023

Dr Nystrom is personable, thorough. Love that

Reviewed on Sep 19, 2023

Dr. Nystrom and his staff are wonderful. He is absolutely the best doctor. He listens to my concerns, explains everything very clearly, discusses options and is genuinely concerned and caring. I will never use another surgeon regardless of where I am located. I currently drive over 2 hours each way for all visits.

Reviewed on Sep 5, 2023

Dr Nystrom is my favorite Doctor. Very caring and very good with everything he has done. He is the best.

Reviewed on Aug 31, 2023

Super knowledgeable, attentive and excellent care. Amazing doctor and staff!

Reviewed on Aug 31, 2023

Dr. Nystrom and his staff are simply the best. They genuinely cared about my condition and recovery. I'm forever grateful!

Reviewed on Aug 29, 2023

Very pleased with Cleveland Clinic and DR. Nystrom and staff

Reviewed on Aug 29, 2023

Doctor Nystrom, Kristi and Mike are so helpful and concerned with all my needs. I would recommend this practice to evevyone.

Reviewed on Jul 13, 2023

All staff in Dr. Nystom's office were friendly and efficient.

Reviewed on Jul 11, 2023

A great doctor

Reviewed on Jul 7, 2023

The surgery performed by Dr Nystrom gave me back my life. I continue to be amazed by the day that I can walk, sit, stand pain free.

Reviewed on Jun 13, 2023

The PA and doctor are very warm, personable, and professional. I felt that they listened to my concerns and provided reasonable suggestions and answers to my questions.

Reviewed on Jun 13, 2023

Dr Nystrom, Kristi and Michael are a wonderful team who work together to provide medical, emotional and physical support to their patients. B I would higher recommend them to others and return to their office should I need additional service from them.

Reviewed on Jun 13, 2023

We always have a wonderful experience with all of the providers at the Cleveland Clinic.

Reviewed on Jun 6, 2023

Have had excellent care at the clinic, And Dr Nystrom is the best I have no complaints.

Reviewed on Jun 1, 2023

Excellent doctors, PA & staff!

Reviewed on Jun 1, 2023

Very good doctor and nice staff

Reviewed on May 25, 2023

Dr. Nystrom is an excellent Doctor/Surgeon. He has always made me feel comfortable and I trust in his professional judgement.

Reviewed on May 25, 2023

I have all of my heath care needs taken care of at the Cleveland Clinic Hillcrest Hospital location. My experience with the Doctor and healthcare workers was very positive.

Reviewed on May 23, 2023

Dr. Nystrom is extraordinarily compassionate and thorough. CC is lucky to have him!

Reviewed on May 9, 2023

Dr. Nystrom is always very professional. He is kind and compassionate and always answers questions thoroughly.

Reviewed on May 9, 2023

Dr. Nystrom is the best!

Reviewed on Apr 21, 2023

Dr Nystrom and his staff were excellent. They took their time with me and explained everything and they gave me times to ask questions. They were very kind and caring. I would recommend them to friends and family

Reviewed on Apr 4, 2023

So glad Dr. Nystrom is my Orthopedic doctor! He is compassionate and concerned about me and my condition.

Reviewed on Mar 17, 2023

Dr.Nystrom is an amazing Dr!!!

Reviewed on Mar 16, 2023

Dr. Nystrom seems to truly care about his patients. He is kind and caring and truly listens to me and about my concerns. I am very blessed to have him as my care giver.

Reviewed on Mar 14, 2023

Dr Nystrom is a wonderful caring Doctor

Reviewed on Mar 7, 2023

Dr. Nystrom is very professional and a joy to work with!

Reviewed on Mar 7, 2023

We were very happy with Dr. Nystrom. We have already mentioned him to friends and family as being excellent at communicating the results and treatment to us. His communication with with us was excellent, he explained everything very well and answered any questions/concerns, made us feel very comfortable about the whole process, and recommended treatment and follow up that was clear and made sense to us. My son, the patient, said that Dr. Nystrom was by far his favorite doctor that he has ever met. In addition, we were seen in a very timely manner and all needs were addressed during the appointment. Thank you so much for taking very good care of my son.

Reviewed on Mar 3, 2023

Dr Nystrom is the best doctor I have ever had and I have had several in the last few years. He talks to you not at you and explains everything and involves you in the conversation always. He always makes sure you know everything is your decision and takes the time to explain everything. I have recommended him to everyone and will continue to do so. He saved my life and he truly cares for his patients.

Reviewed on Feb 3, 2023

Dr.Nystrom and staff always take time to thoroughly answer questions. Very pleased with care and response.

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