Specialty Pharmacy

Overview

Why Choose Cleveland Clinic Specialty Pharmacy?

• Cleveland Clinic is here to be your pharmacy for life. Our specialty pharmacy team consists of pharmacists, pharmacy technicians and nurses that are dedicated to help prepare you to start and to support continuation on these high cost, chronic specialty medications.
• Industry leader. Cleveland Clinic Specialty Pharmacy is one of the largest integrated specialty pharmacies in the country.
• Coordinated care.
• High satisfaction.
• Accredited and trusted. Cleveland Clinic Specialty Pharmacy is URAC accredited.

Our philosophy

Cleveland Clinic Specialty Pharmacy (CCSP) plays a key role in the health care delivery system. CCSP maintains a deep commitment to service and clinical excellence. Key themes that underlie our quality management program include:

• Clinical integrity. We hold ourselves to high standards of clinical integrity in everything we do. Our clinical programs are consistent, defensible and non-biased. The CCSP demonstrates safe, ethical and compliant practice of pharmacy.
• Evidence-based. An evidence-based approach is the conscientious, explicit and judicious use of current best evidence in making decisions. Our evidence-based approach includes: how we apply forward-looking research to improve pharmacy services, evaluate the effectiveness of our programs, measure and evaluate performance and drive quality improvement.
• Voice of the customer. A critical element to a high level of clinical and service quality is ensuring we collect and understand the practice-specific needs through the voice of the customer. Our primary customers are patients and their caregivers, prescribers/physicians, and health plans.

Specialty Medications

What is a specialty medication?

A specialty medication is one prescribed for a patient with a complex or chronic medical condition, typically requiring additional patient education and support, and often associated with high monthly cost. Specialty medications are not readily stocked in retail or local pharmacies.

Cleveland Clinic Specialty Pharmacy (CCSP) is designed for patients who have conditions, including:

Autoimmune/Inflammatory Diseases

This includes dermatology, gastroenterology and rheumatology.

• Tocilizumab (Actemra).
• Tralokinumab-ldrm (Adbry).
• Adalimumab-atto (Amjevita).
• Adalimumab-afzb (Abrilada).
• Repotrectinib (Augtyro).
• Belimumab (Benlysta).
• Bimekizumab-bkzx (Bimzelx).
• Abrocitinib (Cibinqo).
• Certolizumab Pegol (Cimzia).
• Adalimumab-adbm (Cyltezo).
• Secukinumab (Cosentyx).
• Dupilumab (Dupixent).
• Etanercept (Enbrel).
• Vedolizumab (Entyvio).
• Benralizumab (Fasenra).
• Adalimumab-bwwd (Hadlima).
• Adalimumab-fkjp (Hulio).
• Adalimumab (Humira).
• Adalimumab-adaz (Hyrimoz).
• Adalimumab-aacf (Idacio).
• Canakinumab (Ilaris).
• Tildrakizumab (Ilumya).*
• Sarilumab (Kevzara).
• Anakinra (Kineret).
• Voclosporin (Lupyknis).
• Mepolizumab (Nucala).
• Baricitinib (Olumiant).
• Mirikizumab-mrkz (Omvoh).
• Abatacept (Orencia).
• Apremilast (Otezla).
• Methotrexate (Otrexup).
• Methotrexate (Rasuvo).
• Infliximab (Remicade).*
• Upadacitinib (Rinvoq).
• Anifrolumab (Saphnelo).*
• Golimumab (Simponi).
• Brodalumab (Siliq).
• Risankizumab-rzaa (Skyrizi).
• Deucravacitinib (Sotyktu).
• Ustekinumab (Stelara).
• Ixekizumab (Taltz).
• Avacopan (Tavneos).
• Tezepelumab-ekko (Tezspire).*
• Guselkumab (Tremfya).
• Tocilizumab-aazg (Tyenne).
• Etrasimod (Velsipity).
• Tofacitinib (Xeljanz).
• Omalizumab (Xolair).
• Adalimumab-aaty (Yuflyma).
• Adalimumab-aqvh (Yusimry).
• Infliximab-dyyb (Zymfentra).

Hematology/Oncology

• Everolimus (Afinitor).
• Abiraterone/Niraparib (Akeega).
• Alectinib (Alecensa).
• Melphalan (Alkeran).
• Brigatinib (Alunbrig).
• Avapritinib (Ayvakit).
• Erdafitinib (Balversa).
• Ropeginterferon alfa-2b-njft (Besremi).
• Bosutinib (Bosulif).
• Encorafenib (Braftovi).
• Zanabrutinib (Brukinsa).
• Caplacizumab (Cablivi).
• Cabozantinib Tablets (Cabometyx).
• Acalabrutinib (Calquence).
• Cabozantinib Capsules (Cometriq).
• Duvelisib (Copiktra).
• Cobimetinib (Cotellic).
• Eliglustat (Cerdelga).
• Cyclophophamide (Cytoxan).
• Glasdegib (Daurismo).
• Deferiprone.
• Avatrombopag (Doptelet).
• Leuprolide (Eligard).*
• Glutamine (Endari).
• Vismodegib (Erivedge).
• Apalutamide (Erleada).
• Deferasirox Dissolvable Tablets (Exjade).
• Tivozanib (Fotivda).
• Fruquintinib (Fruzaqla).
• Pegfilgrastim-jmdb (Fulphila).
• Pegfilgrastim-pbbk (Fylnetra).
• Pralsetinib (Gavreto).
• Afatinib (Gilotrif).
• Imatinib (Gleevec).
• Lomustine (Gleostine).
• Tbo-filgrastim (Granix).
• Topotecan Capsules (Hycamtin).
• Palbociclib (Ibrance).
• Ponatinib (Iclusig).
• Enasidenib (Idhifa).
• Ibrutinib Capsules and Tablets (Imbruvica).
• Axitinib (Inlyta).
• Decitabine / Cedazuridine (Inqovi).
• Fedratinib (Inrebic).
• Gefitinib (Iressa).
• Deferasirox Tablets and Sprinkles (Jadenu).
• Ruxolitinib (Jakafi).
• Pirtobrutinib (Jaypirca).
• Ribociclib (Kisqali).
• Selumetinib (Koselugo).
• Adagrasib (Krazati).
• Levantinib (Lenvima).
• Chlorambucil (Leukeran).
• Sargramostim (Leukine).
• Trifluridine / Tipiracil (Lonsurf).
• Lorlatinib (Lorbrena).
• Sotorasib (Lumakras).
• Leuprolide (Lupron Depot).
• Olaparib Tablets (Lynparza).
• Procarbazine (Matulane).
• Trametinib (Mekinist).
• Binimetinib (Mektovi).
• Mesna (Mesnex).
• Lusutrombopag (Mulpleta).
• Busulfan (Myleran).
• Neratinib (Nerlynx).
• Pegfilgrastim (Neulasta).
• Filgrastim (Neupogen).
• Sorafenib (Nexavar).
• Ixazomib (Ninlaro).
• Filgrastim-aafi (Nivestym).
• Romiplostim (Nplate).*
• Darolutamide (Nubeqa).
• Pegfilgrastim-apgf (Nyvepria).
• Sonidegib (Odomzo).
• Nirogacestat (Ogsiveo).
• Momelotinib (Ojjaara).
• Azacitadine (Onureg).
• Relugolix (Orgovyx).
• Elacestrant (Orserdu).
• Voxelotor (Oxbryta).
• Peginterferon alfa-2a (Pegasys).
• Pemigatinib (Pemazyre).
• Alpelisib (Piqray).
• Eltrombopag (Promacta).
• Luspatercept-aamt (Reblozyl)*.
• Filgrastim-ayow (Releuko). 
• Selpercatinib (Retevmo).
• Olutasidenib (Rezlidhia).
• Belumosudil (Rezurock).
• Eflapegrastim (Rolvedon).
• Entrectinib (Rozlytrek).
• Rucaparib (Rubraca).
• Midostaurin (Rydapt).
• Ocreotide (Sandostatin).
• Asciminib (Scemblix).
• Dasatinib (Sprycel).
• Pegfilgrastim-fpgk (Stimufend).
• Regorafenib (Stivarga).
• Sunitinib (Sutent).
• Capmatinib (Tabrecta).
• Dabrafenib (Tafinlar).
• Osimertinib (Tagrisso).
• Talazoparib (Talzenna).
• Erlotinib (Tarceva).
• Bexarotene (Targretin).
• Nilotinib (Tasigna).
• Fostamatinib (Tavalisse).
• Tazemetostat (Tazverik).
• Temozolomide (Temodar).
• Tepotinib (Tepmetko).
• Ivosidenib (Tibsovo).
• Capivasertib (Truqap).
• Tucatinib (Tukysa).
• Lapatinib (Tykerb).
• Pegfilgrastim-cbqv (Udenyca).
• Mechlorethamine (Valchlor gel).
• Quizartinib (Vanflyta).
• Venetoclax (Venclexta).
• Etoposide (Vepesid).
• Abemaciclib (Verzenio).
• Tretinoin (Vesanoid).
• Alpelisib (Vijoice).
• Larotrectinib (Vitrakvi).
• Dacomitinib (Vizimpro).
• Pacritinib (Vonjo).
• Pazopanib (Votrient).
• Vorasidenib (Voranigo).
• Belzutifan (Welireg).
• Crizotinib (Xalkori).
• Capecitabine (Xeloda).
• Telotristat ethyl (Xermelo).
• Denosumab (Xgeva).*
• Gilteritinib (Xospata).
• Selinexor (Xpovio).
• Enzalutamide (Xtandi).
• Abiraterone (Yonsa).
• Filgrastim-sndz (Zarxio).
• Niraparib (Zejula).
• Vemurafenib (Zelboraf).
• Pegfilgrastim-bmez (Ziextenzo).
• Vorinostat (Zolinza).
• Idelalisib (Zydelig).
• Ceritinib (Zykadia).
• Abiraterone (Zytiga).

Cardiovascular

• Vutrisiran (Amvuttra).*
• Rilonacept (Arcalyst).
• Mavacamten (Camzyos).
• Vericiguat (Verquvo).
• Tafamidis (Vyndamax).
• Tafamidis (Vyndaqel).
• Eplontersen (Wainua).

General

• Omadacycline (Nuzyra).
• Tedizolid phosphate (Sivextro).
• Nafarelin (Synarel).
• Trientine (Syprine).
• Fecal microbiota spores, live-brpk (Vowst).
• Rifaximin (Xifaxan).

Hepatology

• Entecavir (Baraclude).
• Ribavirin (Copegus).
• Sofosbuvir and Velpatasvir (Epclusa).
• Ledipasvir and Sofosbuvir (Harvoni).
• Glecaprevir and Pibrentasvir (Mavyret).
• Ribavirin (Moderiba).
• Ribavirin (Rebetol).
• Ribavirin (Ribapak).
• Ribavirin (Ribasphere).
• Sofosbuvir (Sovaldi).
• Tenofovir Disoproxil Fumarate (Viread).
• Tenofovir alafenamide (Vemlidy).
• Sofosbuvir, Velpatasvir and Voxilaprevir (Vosevi).
• Additional services available through our Hepatitis C Ambulatory Clinic.

HIV

• Cabotegravir (Apretude).*
• Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate (Atripla).
• Bictegravir, Emtricitabine, and Tenofovir Alafenamide (Biktarvy).
• Cabotegravir (Cabenuva)*
• Emtricitabine, Rilpivirine, and Tenofovir Disoproxil Fumarate (Complera).
• Daclatasvir (Daklinza).
• Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate (Delstrigo).
• Emtricitabine and Tenofovir Alafenamide (Descovy).
• Dolutegravir and Lamivudine (Dovato).
• Rilpivirine (Edurant).
• Emtricitabine (Emtriva).
• Lamivudine (Epivir).
• Abacavir and Lamivudine (Epzicom).
• Atazanavir and Cobicistat (Evotaz).
• Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (Genvoya).
• Etravirine (Intelence).
• Raltegravir (Isentress and Isentress HD).
• Dolutegravir and Rilpivirine (Juluca).
• Ritonavir (Norvir).
• Emtricitabine, Rilpivirine, and Tenofovir Alafenamide (Odefsey).
• Simeprevir (Olysio).
• Doravirine (Pifeltro).
• Darunavir and Cobicistat (Prezcobix).
• Darunavir (Prezista).
• Atazanavir (Reytaz).
• Fostemsavir (Rukobia).
• Maraviroc (Selzentry).
• Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate (Stribild).
• Lenacapavir (Sunlenca)*.
• Efavirenz (Sustiva).
• Efavirenz, Lamivudine, and Tenofovir Disoproxil Fumarate (Symfi and Symfi Lo).
• Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (Symtuza).
• Dolutegravir (Tivicay).
• Abacavir, Dolutegravir, and Lamivudine (Triumeq).
• Emtricitabine and Tenofovir Disoproxil Fumarate (Truvada).
• Tenofovir Disoproxil Fumarate (Viread).
• Elbasvir and Grazoprevir (Zepatier).
• Abacavir (Ziagen).

Neurology

This includes multiple sclerosis.

• Dalfampridine (Ampyra). 
• Apokyn (Apomorphine).
• Teriflunomide (Aubagio).
• Deutetrabenazine (Austedo).
• Interferon Beta-1a (Avonex).
• Monomethyl Fumerate (Bafiertam).
• Interferon Beta-1b (Betaseron).
• Glatiramer Acetate (Copaxone).
• Satralizumab (Enspryng).
• Fingolimod (Gilenya).
• Glatiramer Acetate (Glatopa).
• Levodopa inhalation (Inbrija).
• Valbenazine (Ingrezza).
• Ofatumumab (Kesimpta).
• Apomorphine (Kynmobi).
• Cladribine (Mavenclad).
• Siponimod (Mayzent).
• Droxidopa (Northera).
• Istradefylline (Nourianz).
• Pimavanserin (Nuplazid).
• Ocrelizumab (Ocrevus).
• Opicapone (Ongentys).
• Ponesimod (Ponvory). 
• Peginterferon Beta-1a (Plegridy).
• Interferon Beta-1a (Rebif).
• Levodopa and Carbidopa (Rytary).
• Dimethyl Fumarate (Tecfidera).
• Diroximel fumarate (Vumerity).
• Tetrabenazine.
• Ozanimod (Zeposia).
• Daclizumab (Zinbryta).

Osteoporosis

• Romosozumab (Evenity).* 
• Teriparatide (Forteo).
• Denosumab (Prolia).*
• Abaloparatide (Tymlos).

*For medications with a * next to it, Cleveland Clinic Specialty Pharmacy can only service if it is under prescription benefit.

Contact Us

Specialty Pharmacy serves Cleveland Clinic patients and employees throughout twelve states: Florida, Illinois, Indiana, Michigan, Nevada, New Jersey, New York, Ohio, Pennsylvania, Virginia, West Virginia, Wisconsin and U.S. Virgin Islands.

Medications must be prescribed by a Cleveland Clinic provider and sent electronically to Cleveland Clinic Specialty. Call 216.448.7732 or toll-free 844.216.7732 for additional information.

Hours

• Monday – Friday: 7 a.m. – 6 p.m.
• Saturday – Sunday: Closed.
• Closed for New Year’s Day, Memorial Day, Independence Day, Labor Day, Thanksgiving and Christmas Day.
• 24/7 Clinical Support On-Call Service.

External Specialty Pharmacy - White Bagging

Your insurance is requiring that you obtain your or your family member’s medication through an external specialty pharmacy (e.g. “white bagging”) instead of medication being dispensed from hospital supply. Your insurance plan is partnered with an external specialty pharmacy that requires your medication to be shipped directly to Cleveland Clinic for your upcoming infusion or injection.

Process:

1. Prior Authorization request for Infusion or Injection submitted to insurance plan.
   • Insurance plan approved medication via Pharmacy Benefit (e.g. “White Bagging”).
2. Prescription is sent to your insurance company’s required specialty pharmacy by your healthcare provider.
3. It may take up to seven business days for the specialty pharmacy to process the prescription as well as your insurance information.
4. Your insurance company’s required specialty pharmacy will reach out to you to review first time patient information, any applicable copay, and answer any questions prior to dispensing the medication to Cleveland Clinic.
5. Your insurance company’s required specialty pharmacy will ask for the address to ship the medication. The specific address for your treatment site should be used to ensure that the medication is delivered to the correct address. Addresses for treatment sites can be found at the bottom of this page.
6. Your insurance company’s required specialty pharmacy will require an “okay to ship” from the patient or family member before they will ship the medication to Cleveland Clinic on your behalf.
   • Please be aware that you will receive a call from a toll free number to get this “okay to ship” to Cleveland Clinic. This is a required step to ensure your treatment occurs in a timely manner.
   • Cleveland Clinic employees cannot give this “okay to ship” on your behalf.
   • Some specialty pharmacies will allow a lifetime consent for “okay to ship”.
     • You can ask your insurance company’s required specialty pharmacy if they provide a lifetime consent for an “okay to ship”.
     • If not, please expect a call from your insurance company’s required specialty pharmacy before each future medication is shipped to review prescription and/or copay information.
   • Failure to complete the above “okay to ship” confirmation will result in your medication being delayed and/or needing to be rescheduled.
7. When scheduling the shipment of the medication to Cleveland Clinic, our goal is to schedule the medication to arrive at least one week prior to your appointment.
8. For further questions, please contact your healthcare provider.

Provider Reference for Infusion Suite Addresses