Specialty Pharmacy

Overview

When you have a high-cost prescription to treat a chronic condition, you can rest a little easier knowing the team at Cleveland Clinic Specialty Pharmacy can help. As one of the largest integrated specialty pharmacies in the U.S., our pharmacists, pharmacy technicians and nurses offer comprehensive and coordinated care.

Committed to Quality Care and Service

Trusted and accredited by URAC and ACHC, Cleveland Clinic Specialty Pharmacy maintains a deep commitment to excellence. Our team focuses each day on quality care by:

• Practicing clinical integrity. We uphold clinical integrity in all we do. We ensure our pharmacy programs are consistent, defensible and non-biased. And, every day, our team strives to work safely, ethically and compliantly.
• Trusting evidence-based care. We conscientiously follow the best research evidence when making decisions, including using forward-looking research to improve our services and drive and measure our programs’ effectiveness and quality improvements.
• Respecting your voice. Your opinions and needs matter and play a critical role in delivering high-level care and service. We listen to you — along with your family, care team and health insurer — to make sure your care is what you need.

Accreditations

Specialty Medications

A specialty medication is prescribed for a patient with a complex or chronic medical condition, typically requiring additional patient education and support, and often associated with high monthly cost. Specialty medications are not readily stocked in retail or local pharmacies.

Cleveland Clinic Specialty Pharmacy (CCSP) is designed for patients who have conditions, including:

Autoimmune/Inflammatory Diseases

This includes allergy, dermatology, gastroenterology, pulmonary, and rheumatology.

• Tocilizumab (Actemra).
• Tralokinumab-ldrm (Adbry).
• Adalimumab-atto (Amjevita).
• Adalimumab-afzb (Abrilada).
• Belimumab (Benlysta).
• Bimekizumab-bkzx (Bimzelx).
• Abrocitinib (Cibinqo).
• Certolizumab Pegol (Cimzia).
• Adalimumab-adbm (Cyltezo).
• Secukinumab (Cosentyx).
• Dupilumab (Dupixent).
• Etanercept (Enbrel).
• Vedolizumab (Entyvio).
• Benralizumab (Fasenra).
• Adalimumab-bwwd (Hadlima).
• Adalimumab-fkjp (Hulio).
• Adalimumab (Humira).
• Adalimumab-adaz (Hyrimoz).
• Adalimumab-aacf (Idacio).
• Canakinumab (Ilaris).
• Tildrakizumab (Ilumya).*
• Sarilumab (Kevzara).
• Anakinra (Kineret).
• Voclosporin (Lupyknis).
• Mepolizumab (Nucala).
• Baricitinib (Olumiant).
• Mirikizumab-mrkz (Omvoh).
• Abatacept (Orencia).
• Apremilast (Otezla).
• Methotrexate (Otrexup).
• Methotrexate (Rasuvo).
• Upadacitinib (Rinvoq).
• Golimumab (Simponi).
• Brodalumab (Siliq).
• Risankizumab-rzaa (Skyrizi).
• Deucravacitinib (Sotyktu).
• Ustekinumab (Stelara).
• Ixekizumab (Taltz).
• Avacopan (Tavneos).
• Tezepelumab-ekko (Tezspire).*
• Guselkumab (Tremfya).
• Tocilizumab-aazg (Tyenne).
• Etrasimod (Velsipity).
• Tofacitinib (Xeljanz).
• Omalizumab (Xolair).
• Adalimumab-aaty (Yuflyma).
• Adalimumab-aqvh (Yusimry).
• Infliximab-dyyb (Zymfentra).

Hematology/Oncology

• Everolimus (Afinitor).
• Abiraterone/Niraparib (Akeega).
• Alectinib (Alecensa).
• Melphalan (Alkeran).
• Brigatinib (Alunbrig).
• Repotrectinib (Augtyro).
• Avapritinib (Ayvakit).
• Erdafitinib (Balversa).
• Ropeginterferon alfa-2b-njft (Besremi).
• Bosutinib (Bosulif).
• Encorafenib (Braftovi).
• Zanabrutinib (Brukinsa).
• Caplacizumab (Cablivi).
• Cabozantinib Tablets (Cabometyx).
• Acalabrutinib (Calquence).
• Cabozantinib Capsules (Cometriq).
• Duvelisib (Copiktra).
• Cobimetinib (Cotellic).
• Eliglustat (Cerdelga).
• Cyclophophamide (Cytoxan).
• Glasdegib (Daurismo).
• Deferiprone.
• Avatrombopag (Doptelet).
• Leuprolide (Eligard).*
• Glutamine (Endari).
• Vismodegib (Erivedge).
• Apalutamide (Erleada).
• Deferasirox Dissolvable Tablets (Exjade).
• Tivozanib (Fotivda).
• Fruquintinib (Fruzaqla).
• Pegfilgrastim-jmdb (Fulphila).
• Pegfilgrastim-pbbk (Fylnetra).
• Pralsetinib (Gavreto).
• Afatinib (Gilotrif).
• Imatinib (Gleevec).
• Lomustine (Gleostine).
• Tbo-filgrastim (Granix).
• Topotecan Capsules (Hycamtin).
• Palbociclib (Ibrance).
• Ponatinib (Iclusig).
• Enasidenib (Idhifa).
• Ibrutinib Capsules and Tablets (Imbruvica).
• Axitinib (Inlyta).
• Decitabine / Cedazuridine (Inqovi).
• Fedratinib (Inrebic).
• Gefitinib (Iressa).
• Deferasirox Tablets and Sprinkles (Jadenu).
• Ruxolitinib (Jakafi).
• Pirtobrutinib (Jaypirca).
• Ribociclib (Kisqali).
• Selumetinib (Koselugo).
• Adagrasib (Krazati).
• Levantinib (Lenvima).
• Chlorambucil (Leukeran).
• Sargramostim (Leukine).
• Trifluridine / Tipiracil (Lonsurf).
• Lorlatinib (Lorbrena).
• Sotorasib (Lumakras).
• Leuprolide (Lupron Depot).
• Olaparib Tablets (Lynparza).
• Procarbazine (Matulane).
• Trametinib (Mekinist).
• Binimetinib (Mektovi).
• Mesna (Mesnex).
• Lusutrombopag (Mulpleta).
• Busulfan (Myleran).
• Neratinib (Nerlynx).
• Pegfilgrastim (Neulasta).
• Filgrastim (Neupogen).
• Sorafenib (Nexavar).
• Ixazomib (Ninlaro).
• Filgrastim-aafi (Nivestym).
• Romiplostim (Nplate).*
• Darolutamide (Nubeqa).
• Pegfilgrastim-apgf (Nyvepria).
• Sonidegib (Odomzo).
• Nirogacestat (Ogsiveo).
• Momelotinib (Ojjaara).
• Azacitadine (Onureg).
• Relugolix (Orgovyx).
• Elacestrant (Orserdu).
• Voxelotor (Oxbryta).
• Peginterferon alfa-2a (Pegasys).
• Pemigatinib (Pemazyre).
• Alpelisib (Piqray).
• Eltrombopag (Promacta).
• Luspatercept-aamt (Reblozyl)*.
• Filgrastim-ayow (Releuko). 
• Selpercatinib (Retevmo).
• Olutasidenib (Rezlidhia).
• Belumosudil (Rezurock).
• Eflapegrastim (Rolvedon).
• Entrectinib (Rozlytrek).
• Rucaparib (Rubraca).
• Midostaurin (Rydapt).
• Asciminib (Scemblix).
• Dasatinib (Sprycel).
• Pegfilgrastim-fpgk (Stimufend).
• Regorafenib (Stivarga).
• Sunitinib (Sutent).
• Capmatinib (Tabrecta).
• Dabrafenib (Tafinlar).
• Osimertinib (Tagrisso).
• Talazoparib (Talzenna).
• Erlotinib (Tarceva).
• Bexarotene (Targretin).
• Nilotinib (Tasigna).
• Fostamatinib (Tavalisse).
• Tazemetostat (Tazverik).
• Temozolomide (Temodar).
• Tepotinib (Tepmetko).
• Ivosidenib (Tibsovo).
• Capivasertib (Truqap).
• Tucatinib (Tukysa).
• Lapatinib (Tykerb).
• Pegfilgrastim-cbqv (Udenyca).
• Mechlorethamine (Valchlor gel).
• Quizartinib (Vanflyta).
• Venetoclax (Venclexta).
• Etoposide (Vepesid).
• Abemaciclib (Verzenio).
• Tretinoin (Vesanoid).
• Alpelisib (Vijoice).
• Larotrectinib (Vitrakvi).
• Dacomitinib (Vizimpro).
• Pacritinib (Vonjo).
• Pazopanib (Votrient).
• Vorasidenib (Voranigo).
• Belzutifan (Welireg).
• Crizotinib (Xalkori).
• Capecitabine (Xeloda).
• Telotristat ethyl (Xermelo).
• Denosumab (Xgeva).*
• Gilteritinib (Xospata).
• Selinexor (Xpovio).
• Enzalutamide (Xtandi).
• Abiraterone (Yonsa).
• Filgrastim-sndz (Zarxio).
• Niraparib (Zejula).
• Vemurafenib (Zelboraf).
• Pegfilgrastim-bmez (Ziextenzo).
• Vorinostat (Zolinza).
• Idelalisib (Zydelig).
• Ceritinib (Zykadia).
• Abiraterone (Zytiga).

Cardiovascular

• Vutrisiran (Amvuttra).*
• Rilonacept (Arcalyst).
• Mavacamten (Camzyos).
• Vericiguat (Verquvo).
• Tafamidis (Vyndamax).
• Tafamidis (Vyndaqel).
• Eplontersen (Wainua).

General

• Omadacycline (Nuzyra).
• Ocreotide (Sandostatin).
• Tedizolid phosphate (Sivextro).
• Nafarelin (Synarel).
• Trientine (Syprine).
• Fecal microbiota spores, live-brpk (Vowst).
• Rifaximin (Xifaxan).

Hepatology

Additional services available through our Hepatitis C Ambulatory Clinic.

• Entecavir (Baraclude).
• Ribavirin (Copegus).
• Sofosbuvir and Velpatasvir (Epclusa).
• Ledipasvir and Sofosbuvir (Harvoni).
• Glecaprevir and Pibrentasvir (Mavyret).
• Ribavirin (Moderiba).
• Ribavirin (Rebetol).
• Ribavirin (Ribapak).
• Ribavirin (Ribasphere).
• Sofosbuvir (Sovaldi).
• Tenofovir Disoproxil Fumarate (Viread).
• Tenofovir alafenamide (Vemlidy).
• Sofosbuvir, Velpatasvir and Voxilaprevir (Vosevi).
• Elbasvir and Grazoprevir (Zepatier).

HIV

• Cabotegravir (Apretude).*
• Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate (Atripla).
• Bictegravir, Emtricitabine, and Tenofovir Alafenamide (Biktarvy).
• Cabotegravir (Cabenuva)*
• Emtricitabine, Rilpivirine, and Tenofovir Disoproxil Fumarate (Complera).
• Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate (Delstrigo).
• Emtricitabine and Tenofovir Alafenamide (Descovy).
• Dolutegravir and Lamivudine (Dovato).
• Rilpivirine (Edurant).
• Emtricitabine (Emtriva).
• Lamivudine (Epivir).
• Abacavir and Lamivudine (Epzicom).
• Atazanavir and Cobicistat (Evotaz).
• Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (Genvoya).
• Etravirine (Intelence).
• Raltegravir (Isentress and Isentress HD).
• Dolutegravir and Rilpivirine (Juluca).
• Ritonavir (Norvir).
• Emtricitabine, Rilpivirine, and Tenofovir Alafenamide (Odefsey).
• Doravirine (Pifeltro).
• Darunavir and Cobicistat (Prezcobix).
• Darunavir (Prezista).
• Atazanavir (Reytaz).
• Fostemsavir (Rukobia).
• Maraviroc (Selzentry).
• Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate (Stribild).
• Lenacapavir (Sunlenca)*.
• Efavirenz (Sustiva).
• Efavirenz, Lamivudine, and Tenofovir Disoproxil Fumarate (Symfi and Symfi Lo).
• Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (Symtuza).
• Dolutegravir (Tivicay).
• Abacavir, Dolutegravir, and Lamivudine (Triumeq).
• Emtricitabine and Tenofovir Disoproxil Fumarate (Truvada).
• Tenofovir Disoproxil Fumarate (Viread).
• Abacavir (Ziagen).

Neurology

This includes multiple sclerosis.

• Dalfampridine. 
• Apokyn (Apomorphine).
• Teriflunomide (Aubagio).
• Deutetrabenazine (Austedo).
• Interferon Beta-1a (Avonex).
• Monomethyl Fumerate (Bafiertam).
• Interferon Beta-1b (Betaseron).
• Glatiramer Acetate (Copaxone).
• Satralizumab (Enspryng).
• Fingolimod (Gilenya).
• Glatiramer Acetate (Glatopa).
• Levodopa inhalation (Inbrija).
• Valbenazine (Ingrezza).
• Ofatumumab (Kesimpta).
• Cladribine (Mavenclad).
• Siponimod (Mayzent).
• Droxidopa (Northera).
• Istradefylline (Nourianz).
• Pimavanserin (Nuplazid).
• Ocrelizumab (Ocrevus).
• Opicapone (Ongentys).
• Ponesimod (Ponvory). 
• Peginterferon Beta-1a (Plegridy).
• Interferon Beta-1a (Rebif).
• Levodopa and Carbidopa (Rytary).
• Dimethyl Fumarate (Tecfidera).
• Diroximel fumarate (Vumerity).
• Tetrabenazine.
• Ozanimod (Zeposia).

Osteoporosis

• Romosozumab (Evenity).* 
• Teriparatide (Forteo).
• Denosumab (Prolia).*
• Abaloparatide (Tymlos).

*For medications with a * next to it, Cleveland Clinic Specialty Pharmacy can only service if it is under prescription benefit.

Contact Us

When you choose Cleveland Clinic Specialty Pharmacy, a Cleveland Clinic provider must prescribe your medications and send them electronically to our department. You can use this service if you live in:

• Florida
• Illinois
• Indiana
• Michigan
• Nevada
• New Jersey
• New York
• Ohio
• Pennsylvania
• Virginia
• West Virginia
• Wisconsin
• U.S. Virgin Islands

Hours

• Monday – Friday: 7 a.m. – 6 p.m.
• Saturday – Sunday: Closed
• Closed for New Year’s Day, Memorial Day, Independence Day, Labor Day, Thanksgiving and Christmas Day
• 24/7 Clinical Support On-Call Service

For more information, call 216.448.7732 or toll-free 844.216.7732.

Hepatitis C Ambulatory Service

Have you been diagnosed with hepatitis C and now need quality, convenient care? Cleveland Clinic Specialty Pharmacy’s virtual clinic may be the right treatment path for you.

Referrals & Appointments

Our pharmacists will start building a personalized care plan with a referral from your healthcare provider. Don’t worry if your provider isn’t affiliated with Cleveland Clinic or you’re looking for a new one. Our team can connect you with a Cleveland Clinic primary care provider so you can use our services.

You won’t need to book an in-person appointment. Our team handles everything in just a few phone calls or MyChart messages. All you need to do is respond when we reach out to you.

We’ll prescribe easy-to-take pills for a relatively short treatment. And you won’t have to wait long to start because your prescriptions will ship directly to your home.

Call 216.448.7732 (select option 3), talk with one of our specially trained hepatitis C pharmacists — and get started today.

Third-Party Pharmacies

Sometimes, insurance companies may require you to order your treatment medication through a third-party pharmacy instead of us. You may have heard this called “white bagging.” If this is the case, we can still help you get the medication you need for your regular infusion or injection.

Your insurance plan’s third-party insurance partner will ship your medication directly to your Cleveland Clinic treatment site, and they will have it ready for upcoming treatment here at Cleveland Clinic. Your treatment site’s goal is to schedule delivery at least a week before your appointment.

How Your Medication Gets to Your Cleveland Clinic Treatment Site

There are a few things that will happen before your prescription reaches your Cleveland Clinic treatment site.

• Prior authorization. Your provider submits a prior authorization request for your infusion or injection to your insurance plan. Your insurer then uses your pharmacy benefits to approve the request (white bagging).
• Prescription request. Once you have an approved prior authorization, your healthcare provider will send your prescription to the required third-party specialty pharmacy.
• Filling your prescription. It may take up to seven days for the third-party pharmacy to process this request. They will contact you to go over your patient information, request any copays and answer your questions before they ship the medication to your Cleveland Clinic treatment site.
• Shipping the medication. The third-party pharmacy will deliver your prescription to your Cleveland Clinic treatment site. They’ll call you to get approval to ship the medication. This is known as an “OK to ship.” Cleveland Clinic can’t approve this for you. Some insurance plans accept a one-time approval for all future shipments If yours doesn’t, you’ll have to approve it each time you have an infusion or injection.

Infusion Site Addresses