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Cardiomyopathy refers to diseases of the heart muscle. These diseases have a variety of causes, symptoms, and treatments.

In cardiomyopathy, the heart muscle becomes enlarged, thick, or rigid. In rare cases, the muscle tissue in the heart is replaced with scar tissue.

As cardiomyopathy worsens, the heart becomes weaker. It's less able to pump blood through the body and maintain a normal electrical rhythm. This can lead to heart failure or arrhythmia. In turn, heart failure can cause fluid to build up in the lungs, ankles, feet, legs, or abdomen.

The weakening of the heart also can cause other severe complications, such as heart valve problems.


The four main types of cardiomyopathy are:

The different types of the disease have different causes, signs and symptoms, and outcomes.

Cardiomyopathy can be acquired or inherited. "Acquired" means you aren't born with the disease but you develop it due to another disease, condition, or factor. "Inherited" means your parents passed the gene for the disease on to you. In many cases, the cause of cardiomyopathy isn't known.

Cardiomyopathy can affect people of all ages. However, certain age groups are more likely to have certain types of cardiomyopathy. This document focuses on cardiomyopathy in adults.


Some people who have cardiomyopathy have no signs or symptoms and need no treatment. For other people, the disease develops rapidly, symptoms are severe, and serious complications occur.

Treatments for cardiomyopathy include lifestyle changes, medicines, surgery, implanted devices to correct arrhythmias, and a nonsurgical procedure. These treatments can control symptoms, reduce complications, and stop the disease from getting worse.

Types of Cardiomyopathy

Dilated Cardiomyopathy

Dilated cardiomyopathy is the most common type of the disease. It mostly occurs in adults aged 20 to 60. Men are more likely than women to have this type of cardiomyopathy.

Dilated cardiomyopathy affects the heart's ventricles and atria. These are the lower and upper chambers of the heart, respectively.

The disease often starts in the left ventricle, the heart's main pumping chamber. The heart muscle begins to dilate (stretch and become thinner). This causes the inside of the chamber to enlarge. The problem often spreads to the right ventricle and then to the atria as the disease gets worse.

When the chambers dilate, the heart muscle doesn't contract normally. Also, the heart can't pump blood very well. Over time, the heart becomes weaker and heart failure can occur. Symptoms of heart failure include fatigue (tiredness); swelling of the ankles, feet, legs, and abdomen; and shortness of breath.

Dilated cardiomyopathy also can lead to heart valve problems, arrhythmias, and blood clots in the heart.

Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy is very common and can affect people of any age. About 1 out of every 500 people has this type of cardiomyopathy. It affects men and women equally. Hypertrophic cardiomyopathy is the most common cause of sudden cardiac arrest (SCA) in young people, including young athletes.

This type of cardiomyopathy occurs when the walls of the ventricles (usually the left ventricle) thicken. Despite this thickening, the ventricle size often remains normal.

Hypertrophic cardiomyopathy may block blood flow out of the ventricle. When this happens, the condition is called obstructive hypertrophic cardiomyopathy. In some cases, the septum thickens and bulges into the left ventricle. (The septum is the wall that divides the left and right sides of the heart.) In both cases, blood flow out of the left ventricle is blocked.

As a result of the blockage, the ventricle must work much harder to pump blood out to the body. Symptoms can include chest pain, dizziness, shortness of breath, or fainting.

Hypertrophic cardiomyopathy also can affect the heart's mitral valve, causing blood to leak backward through the valve.

Sometimes the thickened heart muscle doesn't block blood flow out of the left ventricle. This is called nonobstructive hypertrophic cardiomyopathy. The entire ventricle may become thicker, or the thickening may happen only at the bottom of the heart. The right ventricle also may be affected.

In both types (obstructive and nonobstructive), the thickened muscle makes the inside of the left ventricle smaller, so it holds less blood. The walls of the ventricle also may stiffen. As a result, the ventricle is less able to relax and fill with blood.

These changes cause increased blood pressure in the ventricles and the blood vessels of the lungs. Changes also occur to the cells in the damaged heart muscle. This may disrupt the heart's electrical signals and lead to arrhythmias.

Rarely, people who have hypertrophic cardiomyopathy have no signs or symptoms, and the condition doesn't affect their lives. Others have severe symptoms and complications, such as serious arrhythmias, an inability to exercise, or extreme fatigue with little physical activity.

Rarely, people who have this type of cardiomyopathy can have SCA during very vigorous physical activity. The physical activity can trigger dangerous arrhythmias. If you have this type of cardiomyopathy, talk to your doctor about what types and amounts of physical activity are safe for you.

Restrictive Cardiomyopathy

Restrictive cardiomyopathy tends to mostly affect older adults. In this type of the disease, the ventricles become stiff and rigid. This is due to abnormal tissue, such as scar tissue, replacing the normal heart muscle.

As a result, the ventricles can't relax normally and fill with blood, and the atria become enlarged. Over time, blood flow in the heart is reduced. This can lead to problems such as heart failure or arrhythmias.

Arrhythmogenic Right Ventricular Dysplasia

Arrhythmogenic right ventricular dysplasia (ARVD) is a rare type of cardiomyopathy. ARVD occurs when the muscle tissue in the right ventricle dies and is replaced with scar tissue.

This process disrupts the heart's electrical signals and causes arrhythmias. Symptoms include palpitations and fainting after physical activity.

ARVD usually affects teens or young adults. It can cause SCA in young athletes. Fortunately, such deaths are rare.

Other Names for Cardiomyopathy
  • Alcoholic cardiomyopathy. This term is used when overuse of alcohol causes the disease.
  • Congestive cardiomyopathy.
  • Diabetic cardiomyopathy.
  • Familial dilated cardiomyopathy.
  • Idiopathic cardiomyopathy.
  • Ischemic cardiomyopathy. This term is used when coronary artery disease or heart attack causes the disease.
  • Peripartum cardiomyopathy. This term is used when the disease develops in a woman shortly before or after she gives birth.
  • Primary cardiomyopathy.
Other names for Hypertrophic Cardiomyopathy
  • Asymmetric septal hypertrophy
  • Familial hypertrophic cardiomyopathy
  • Hypertrophic nonobstructive cardiomyopathy
  • Hypertrophic obstructive cardiomyopathy
  • Idiopathic hypertrophic subaortic stenosis
Other names for Restrictive Cardiomyopathy
  • Infiltrative cardiomyopathy
Other names for Arrhythmogenic Right Ventricular Dysplasia
  • Arrhythmogenic right ventricular cardiomyopathy
  • Right ventricular cardiomyopathy
  • Right ventricular dysplasia

What causes Cardiomyopathy?

Cardiomyopathy can be acquired or inherited. "Acquired" means you aren't born with the disease, but you develop it due to another disease, condition, or factor.

"Inherited" means your parents passed the gene for the disease on to you. Researchers continue to look for the genetic links to cardiomyopathy. They also continue to explore how these links cause or contribute to the various types of cardiomyopathy.

Many times, the cause of cardiomyopathy isn't known. This is often the case when the disease occurs in children.

Dilated Cardiomyopathy

In more than half of the cases of dilated cardiomyopathy, the cause isn't known. As many as one-third of the people who have dilated cardiomyopathy inherit it from their parents.

Certain diseases, conditions, and substances also can cause the disease, such as:

Hypertrophic Cardiomyopathy

Most cases of hypertrophic cardiomyopathy are inherited. It also can develop over time because of high blood pressure or aging.

Sometimes, other diseases, such as diabetes or thyroid disease, can cause hypertrophic cardiomyopathy. Sometimes the cause of hypertrophic cardiomyopathy isn't known.

Restrictive Cardiomyopathy

Certain diseases and conditions can cause restrictive cardiomyopathy, including:

  • Hemochromatosis. This is a disease in which too much iron builds up in your body. The extra iron is toxic to the body and can damage the organs, including the heart.
  • Sarcoidosis. This is a disease that causes inflammation (swelling). It can affect various organs in the body. The swelling is due to an abnormal immune response. This abnormal response causes tiny lumps of cells to form in the body's organs, including the heart.
  • Amyloidosis. This is a disease in which abnormal proteins build up in the body's organs, including the heart.
  • Connective tissue disorders.
Arrhythmogenic Right Ventricular Dysplasia

Researchers think that arrhythmogenic right ventricular dysplasia is an inherited disease.

Who is at risk for Cardiomyopathy?

People of all ages can have cardiomyopathy. However, certain types of the disease are more common in certain groups.

Dilated cardiomyopathy is more common in African Americans than in Whites. This type of the disease also is more common in men than women.

Teens and young adults are more likely than older people to have arrhythmogenic right ventricular dysplasia, although it's rare in both groups.

Major risk factors

Certain diseases, conditions, or factors can raise your risk for cardiomyopathy. Major risk factors include:

  • A family history of cardiomyopathy, heart failure, or sudden cardiac arrest (SCA)
  • A disease or condition that can lead to cardiomyopathy, such as coronary artery disease, heart attack, or a viral infection that inflames the heart muscle
  • Diabetes, other metabolic diseases, or severe obesity
  • Diseases that can damage the heart, such as hemochromatosis, sarcoidosis, or amyloidosis
  • Long-term alcoholism
  • Long-term high blood pressure

Some people who have cardiomyopathy never have signs or symptoms. That's why it's important to identify people who may be at high risk for the disease. This can help prevent future problems, such as serious arrhythmias or SCA.

What are the signs and symptoms of Cardiomyopathy?

Some people who have cardiomyopathy never have signs or symptoms. Others don't have signs or symptoms in the early stages of the disease.

As cardiomyopathy worsens and the heart weakens, signs and symptoms of heart failure usually occur. These signs and symptoms include:

  • Shortness of breath or trouble breathing.
  • Fatigue (tiredness).
  • Swelling in the ankles, feet, legs, and abdomen. Rarely, swelling may occur in the veins of your neck.

Other signs and symptoms can include dizziness, lightheadedness, fainting during physical activity, chest pain, arrhythmias, and heart murmur (an extra or unusual sound heard during a heartbeat).

How is Cardiomyopathy diagnosed?

Your doctor will diagnose cardiomyopathy based on your medical history, a physical exam, and the results from tests and procedures.

Specialists involved

Often, a cardiologist or pediatric cardiologist diagnoses and treats cardiomyopathy. A cardiologist is a doctor who specializes in treating heart diseases. A pediatric cardiologist is a doctor who specializes in treating heart diseases in children.

Medical history

Your doctor will want to learn about your medical history. He or she will want to know what symptoms you have and how long you've had them. Your doctor also will want to know whether anyone in your family has had cardiomyopathy, heart failure, or sudden cardiac arrest.

Physical exam

Your doctor will use a stethoscope to listen to your heart and lungs for sounds that may suggest cardiomyopathy. These sounds may even suggest a certain type of the disease.

For example, the loudness, timing, and location of a heart murmur may suggest hypertrophic obstructive cardiomyopathy. A "crackling" sound in the lungs may be a sign of heart failure. (This condition often develops in the later stages of cardiomyopathy.)

Physical signs also help your doctor diagnose cardiomyopathy. Swelling of the ankles, feet, legs, or abdomen suggests fluid buildup, a sign of heart failure.

Signs or symptoms of cardiomyopathy may be found during a routine exam. For example, your doctor may hear a heart murmur or you may have abnormal test results.

Diagnostic tests

You may have one or more of the following tests to diagnose cardiomyopathy.

Blood tests: During a blood test, a small amount of blood is taken from your body. It's usually drawn from a vein in your arm using a thin needle. The procedure usually is quick and easy, although it may cause some short-term discomfort.

Blood tests give your doctor information about your heart and help rule out other conditions.

Chest x ray: A chest x ray takes pictures of the organs and structures inside your chest, including your heart, lungs, and blood vessels. This test can show whether your heart is enlarged. A chest x ray also can show whether fluid is building up in your lungs.

EKG (electrocardiogram): An EKG is a simple test that records the heart's electrical activity. This test shows how fast your heart is beating and whether the rhythm of your heartbeat is steady or irregular. An EKG also records the strength and timing of electrical signals as they pass through each part of your heart.

This test is used to detect and study many heart problems, such as heart attack, arrhythmia, and heart failure. EKG results also can suggest other disorders that affect heart function.

Echocardiography: Echocardiography is a test that uses sound waves to create a moving picture of your heart. The picture shows how well your heart is working and its size and shape.

There are several different types of echocardiography, including a stress echocardiogram, or "stress echo." This test is done as part of a stress test. A stress echo can show whether you have decreased blood flow to your heart, a sign of coronary artery disease.

Another type of echo is a transesophageal echo, or TEE. TEE provides a view of the back of the heart.

For a TEE, a sound wave wand is put on the end of a special tube. The tube is gently passed down your throat and into your esophagus (the passage leading from your mouth to your stomach). You will be given medicine to relax you during this procedure.

Stress test: Some heart problems are easier to diagnose when your heart is working hard and beating fast. During stress testing, you exercise (or are given medicine) to make your heart work hard and beat fast while heart tests are done.

These tests may include nuclear heart scanning, echocardiography, magnetic resonance imaging (MRI), and positron emission tomography (PET) scanning of the heart.

Diagnostic procedures

You may have one or more medical procedures to confirm a diagnosis or if surgery is planned. These procedures may include cardiac catheterization, coronary angiography, or myocardial biopsy.

Cardiac Catheterization: This procedure checks the pressure and blood flow in your heart's chambers. The procedure also allows your doctor to collect blood samples and look at your heart's arteries using x-ray imaging.

During cardiac catheterization, a long, thin, flexible tube called a catheter is put into a blood vessel in your arm, groin (upper thigh), or neck and threaded to your heart. This allows your doctor to study the inside of your arteries to look for blockages.

Coronary Angiography: This procedure often is done with cardiac catheterization. During the procedure, dye that can be seen on an x ray is injected into your coronary arteries. The dye lets your doctor study the flow of blood through your heart and blood vessels.

Dye also may be injected into your heart chambers. This allows your doctor to study the pumping function of your heart.

Myocardial biopsy: For this procedure, your doctor removes a piece of your heart muscle. This can be done during cardiac catheterization. The heart muscle is studied under a microscope to see whether changes in cells have occurred that may suggest cardiomyopathy.

The biopsy is useful for diagnosing some types of cardiomyopathy.

Genetic testing

Some types of cardiomyopathy run in families. Thus, your doctor may suggest genetic testing to look for the disease in your parents, brothers and sisters, or other family members.

Genetic testing can show how the disease runs in families. It also can find out the chances of parents passing the genes for the disease on to their children.

Genetic testing also may be useful if your doctor thinks you may have cardiomyopathy, but you don't yet have signs or symptoms. Your doctor can then start treatment early, when it may be more effective.

How is Cardiomyopathy treated?

Not everyone who has cardiomyopathy needs treatment. People who have no signs or symptoms may not need treatment. In some cases, dilated cardiomyopathy that comes on suddenly may even go away on its own.

For other people who have cardiomyopathy, treatment is needed. Treatment depends on the type of cardiomyopathy you have, how severe the symptoms and complications are, and your age and overall health.

The main goals of treating cardiomyopathy are to:

  • Manage any conditions that cause or contribute to the disease
  • Control signs and symptoms so that you can live as normally as possible
  • Stop the disease from getting worse
  • Reduce complications and the chance of sudden cardiac arrest (SCA)

Treatments may include lifestyle changes, medicines, surgery, implanted devices to correct arrhythmias, and a nonsurgical procedure.

Lifestyle changes

Your doctor may suggest lifestyle changes to manage a condition that's causing your cardiomyopathy. These changes can help reduce symptoms.

Healthy diet and physical activity

A healthy diet and physical activity are part of a healthy lifestyle. A healthy diet includes a variety of fruits, vegetables, and grains; half of your grains should come from whole-grain products.

Choose foods that are low in saturated fat, trans fat, and cholesterol. Healthy choices include lean meats, poultry without skin, fish, beans, and fat-free or low-fat milk and milk products.

Choose and prepare foods with little sodium (salt). Too much salt can raise your risk for high blood pressure. Recent studies show that following the Dietary Approaches to Stop Hypertension (DASH) eating plan can lower blood pressure.

Choose foods and beverages that are low in added sugar. If you drink alcoholic beverages, do so in moderation.

Aim for a healthy weight by staying within your daily calorie needs. Balance the calories you take in with the calories you use while doing physical activity. Be as physically active as you can.

Some people should get medical advice before starting or increasing physical activity. For example, talk to your doctor if you have a chronic (ongoing) health problem, are on medicine, or have symptoms such as chest pain, shortness of breath, or dizziness. Your doctor can suggest types and amounts of physical activity that are safe for you.

Your doctor can help you decide what kind of eating plan and physical activity are right for you.

Other lifestyle changes

Your doctor also may recommend other lifestyle changes, such as:


A number of medicines are used to treat cardiomyopathy. Your doctor may prescribe medicines to:

  • Lower your blood pressure. ACE inhibitors, angiotensin II receptor blockers, beta blockers, and calcium channel blockers are examples of medicines that lower blood pressure.
  • Slow your heart rate. Beta blockers, calcium channel blockers, and digoxin are examples of medicines that slow the heart rate. Beta blockers and calcium channel blockers also are used to lower blood pressure.
  • Keep your heart beating with a normal rhythm. These medicines help prevent arrhythmias.
  • Balance electrolytes in your body. Electrolytes are minerals that help maintain fluid levels and acid-base balance in the body. They also help muscle and nerve tissues work properly. Abnormal electrolyte levels may be a sign of dehydration (lack of fluid in your body), heart failure, high blood pressure, or other disorders. Aldosterone blockers are an example of a medicine used to balance electrolytes.
  • Remove excess fluid and sodium (salt) from your body. Diuretics, or "water pills," are an example of a medicine that helps remove excess fluid and sodium from the body.
  • Prevent blood clots from forming. Anticoagulants, or "blood thinners," are an example of a medicine that prevents blood clots. Blood thinners often are used to prevent blood clots from forming in people who have dilated cardiomyopathy.
  • Reduce inflammation. Corticosteroids are an example of a medicine used to reduce inflammation.


Several different types of surgery are used to treat cardiomyopathy. These include septal myectomy, implanted devices to help the heart work better, and heart transplant.

Septal Myectomy

Septal myectomy is open-heart surgery. It's used for people who have hypertrophic obstructive cardiomyopathy and severe symptoms. This surgery generally is used for younger patients and for people whose medicines aren't working well.

During the surgery, a surgeon removes part of the thickened septum that's bulging into the left ventricle. This improves blood flow through the heart and out to the body. The removed tissue doesn't grow back.

The surgeon also can repair or replace the mitral valve at the same time (if needed). Septal myectomy often is successful and allows you to return to a normal life with no symptoms.

Surgically implanted devices

Surgeons can place several types of devices in the heart to help it work better. One example is a pacemaker. This is a small device that's placed under the skin of your chest or abdomen to help control abnormal heart rhythms. The device uses electrical pulses to prompt the heart to beat at a normal rate.

Sometimes doctors choose to use a biventricular pacemaker. This device coordinates contractions between the heart's left and right ventricles.

A left ventricular assist device (LVAD) helps the heart pump blood to the body. An LVAD can be used as a long-term therapy or as a short-term treatment for people who are waiting for a heart transplant.

An implantable cardioverter defibrillator (ICD) helps control life-threatening arrhythmias, which may lead to SCA. This small device is implanted in the chest or abdomen and connected to the heart with wires.

If an ICD senses a dangerous change in heart rhythm, it will send an electric shock to the heart to restore a normal heartbeat.

Heart transplant

For this surgery, a doctor replaces a person's diseased heart with a healthy heart from a deceased donor. Heart transplant is a last resort treatment for people who have end-stage heart failure. "End-stage" means the condition has become so severe that all treatments, other than heart transplant, have failed.

Nonsurgical procedure

Doctors may use a nonsurgical procedure called alcohol septal ablation to treat cardiomyopathy.

For this procedure, your doctor injects ethanol (a type of alcohol) through a catheter into the small artery that supplies blood to the thickened area of heart muscle. The alcohol kills cells, and the thickened tissue shrinks to a more normal size.

This allows blood to flow freely through the ventricle, and symptoms improve.

How can Cardiomyopathy be prevented?

You can't prevent inherited types of cardiomyopathy. However, you can take steps to lower your risk for conditions that may lead to or complicate cardiomyopathy, such as coronary artery disease, high blood pressure, and heart attack.

Your doctor may advise you to make lifestyle changes, such as following a healthy diet and doing physical activity.

Living with Cardiomyopathy

Some people who have cardiomyopathy—especially those who have the hypertrophic type—may live a healthy life with few problems or symptoms. Others may have serious symptoms and complications.

If you have cardiomyopathy, you can take steps to take care of your heart. Lifestyle changes and ongoing care can help you manage your disease.

Lifestyle changes

A healthy diet and physical activity are part of a healthy lifestyle. Your doctor can help you decide what kind of eating plan is right for you.

Talk with your doctor about the amounts and types of fluids that are safe and healthy for you. Your doctor also may suggest a diet that's low in sodium (salt) and fat.

Talk with your doctor about the amount and type of physical activity that's right for you. People who have hypertrophic cardiomyopathy shouldn't do vigorous exercise. However, moderate exercise, such as walking, often is a good idea.

Your doctor also may recommend other lifestyle changes, such as:

  • Quitting smoking
  • Losing excess weight
  • Avoiding the use of alcohol and illegal drugs
  • Getting enough sleep and rest
  • Reducing stress
Ongoing care

If you have cardiomyopathy, it's important to get ongoing care. Call your doctor if you notice new or worse symptoms, such as swelling in your ankles, feet, legs, or abdomen. These symptoms may be a sign that the disease is getting worse.

You also should:

  • Take all of your medicines as your doctor prescribes.
  • Make all of the lifestyle changes that your doctor recommends.
  • Make sure you go to all of your medical checkups.
  • Follow your treatments for any underlying conditions, such as diabetes and high blood pressure.

Cardiomyopathy often runs in families. Your doctor may suggest that your parents, brothers and sisters, and children get checked to see whether they have the disease.

Source: National Institutes of Health; National Heart, Lung, and Blood Institute

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This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. This document was last reviewed on: 12/30/2008...#5846


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