Marfan syndrome affects the connective tissue. It can cause problems in many parts of the body, including your joints, bones, eyes, heart and blood vessels. If you have Marfan syndrome and are considering pregnancy, it is very important to talk to your doctor. The condition and treatments increase the chance of problems for both you and your unborn baby.
Pregnancy creates extra stress on the heart and blood vessels. The biggest concern for patients with Marfan syndrome is serious complications of the aorta, such as a tear or rupture that can cause death or serious injury to both you and your unborn baby. The risk is greatest if your aorta is dilated more than 4 cm. If this is the case, you should wait to become pregnant until after you have surgery to repair your aorta.
Your doctor will talk to you about the best options for delivery. If you have a dilated aorta, you will likely have a cesarean section. Otherwise, you can probably deliver vaginally. An epidural can help keep your blood pressure stable and reduce the strain on your heart and blood vessels during labor.
Because Marfan syndrome is a genetic disorder, your children have 50% chance of having the disease. If the genetic cause of your Marfan syndrome is known, your children can be tested for the condition during pregnancy (using amniocentesis) or after birth (with a blood test). If the exact cause is not known, your children should have close medical follow-up during their lives to check for signs of the disease.