Neuromodulatory Therapy With Responsive Neural Stimulation

Seizure Outcomes in Patients Undergoing RNS Placement at Cleveland Clinic (N = 43)

2020 Responsive Neurostimulation for Epilepsy Outcomes

The graph shows percent seizure reduction (most recent 3-month patient-reported seizure frequency compared with the pre-responsive neural stimulation (RNS) baseline seizure frequency) of 43 patients who were implanted with the responsive neurostimulation device at Cleveland Clinic and had > 6 months of accurate seizure reporting.

Two out of 3 (70%) patients have achieved > 50% reduction in their seizure frequency over time.

Location of Responsive Neurostimulation (RNS) Lead Placement

Responsive neural stimulation (RNS) has 2 active leads per device. Above figure highlights Cleveland Clinic's experience with lead placements in various brain regions, outside of the typical mesial temporal regions.