The graph shows percent seizure reduction from baseline seizure frequency of 32 patients who were implanted with a responsive neural stimulation (RNS) device at Cleveland Clinic. These patients were implanted with the RNS device from 2010 until 2019. Patients ages ranged from 19-62 years. Almost 20% of our patients have achieved a greater than 90% reduction in their seizure frequency over time. About 70% of patients have some reduction of their baseline seizure frequency with this therapy. Six patients have less than one year of follow up. The median duration of follow up is 3 years (range 8 months to 10 years).