Movement Disorders

Deep Brain Stimulation

Motor Scores Before and After Deep Brain Stimulation for Parkinson Disease (N = 28)


DBS = deep brain stimulation

The Movement Disorders Society – Unified Parkinson’s Disease Rating Scale Part III (MDS-UPDRS-III) is a clinician rating scale of motor symptoms of Parkinson disease (PD) including tremor, bradykinesia, rigidity, gait, posture, speech, and facial expression. Higher numbers reflect worse symptoms. Twenty-eight patients who underwent deep brain stimulation (DBS) were assessed using the UPDRS-III both before and after surgery while off and on medications. Median time to follow-up was 145 days (range, 76-485). The graph shows mean clinician-rated motor impairment severity ± 2 standard errors of the mean. There was a significant improvement in motor scores after surgery in both medication states (paired-samples t > 5.0, P < 0.001). Cleveland Clinic has been designated a Parkinson's Disease Foundation Center of Excellence. Fluctuations in 2020 volumes are a result of the COVID-19 pandemic.