CMS calculates 2 acute ischemic stroke outcomes measures based on Medicare claims and enrollment information. The most recent risk-adjusted data available from CMS are shown. Although Cleveland Clinic’s stroke patient mortality and readmission rates are slightly higher than the US national rate, CMS ranks Cleveland Clinic’s performance as “no different” than the US national rate. To further reduce avoidable readmissions, Cleveland Clinic is focused on optimizing transitions from hospital to home or post-acute facility. Specific initiatives have been implemented to ensure effective communication, education, and follow-up.