Neurological Institute Outcomes
Epilepsy
Pediatric Epilepsy
Pediatric Epilepsy: Effect of Treatment on Mood
2009 – 2022
Medical Patients — CES-DC (N = 276)
A total of 276 medically treated pediatric epilepsy patients seen from 2009 through 2022 had two Center for Epidemiological Studies-Depression scale (CES-DC) scores at least 180 days apart. Of these, 29% improved, 36% remained stable, and 35% worsened. Clinically meaningful change was defined as a total point change of ≥ 5 based on one-half the standard deviation of the baseline score.¹ Median time between questionnaire completions was 1025 days (range, 182-4338 days).
Surgical Patients — CES-DC (N = 84)
A total of 84 surgically treated pediatric epilepsy patients seen from 2009 through 2022 had two Center for Epidemiological Studies-Depression scale (CES-DC) scores at least 180 days apart. Of these, 45% improved, 30% remained stable, and 25% worsened. Clinically meaningful change was defined as a total point change of ≥ 5 based on one-half the standard deviation of the baseline score.¹ Median time between questionnaire completions was 501 days (range, 181-3391 days).
Pediatric Epilepsy: Effect of Treatment on Quality of Life
2008 – 2022
Medical Patients (N = 958)
A total of 958 medically treated pediatric epilepsy patients seen from 2008 through 2022 had two Child’s Overall Quality of Life ( QOL) scores at least 180 days apart. Of these, 31% improved, 44% remained stable, and 25% worsened. Clinically meaningful change was defined as a total point change of ≥ 1 based on one-half the standard deviation of the baseline score.¹ Median time between questionnaire completions was 1332.5 days (range, 181-5116 days).
Surgical Patients (N = 288)
A total of 288 surgically treated pediatric epilepsy patients seen from 2008 through 2022 had two Child’s Overall QOL scores at least 180 days apart. Of these, 58% improved, 30% remained stable, and 12% worsened. Clinically meaningful change was defined as a total point change of ≥ 1 based on one-half the standard deviation of the baseline score.¹ Median time between questionnaire completions was 714.5 days (range, 184-4892 days).
