Neurological Institute Outcomes
Epilepsy
Adult Epilepsy: Effect of Treatment on Global Mental Health
Change in Global Mental Health in Adult Epilepsy Patients
2014 – 2022
Medical Patients (N = 3257)
6893 medically treated patients had at least 2 visits with PROMIS-10 Mental Health data available for analysis. Among those patients whose baseline PROMIS-10 Mental Health score ≤ 45 (N = 3257), 33.7% (N = 1099) showed improvement, 51.2% (N = 1669) remained stable, and 15% (N = 489) worsened. Median duration of follow-up was 1282 days (range, 180-2976 days).
Surgical Patients (N = 129)
212 surgical patients had a presurgery visit and postsurgery visit with PROMIS-10 Mental Health data available for analysis. Among those patients whose baseline PROMIS-10 Mental Health score ≤ 45 (N = 129), 36.4% (N = 47) showed improvement, 45% (N = 58) remained stable, and 18.6% (N = 24) worsened. Median duration of follow-up was 799 days (range, 188-2570 days). Clinically meaningful change was defined as a 5-point change in T-score, based on one-half the standard deviation.²