Epilepsy

Adult Epilepsy: Effect of Treatment on Quality of Life

2007 - 2021

Improvement in Quality of Life in Medically Treated Adult Epilepsy Patients (N = 3664)

2007 – 2021

QOLIE-10 = Quality of Life in Epilepsy questionnaire

In medically treated patients, the mean QOLIE-10 score improved from 21.8 at initial visit to 20.9 at last follow-up (P < 0.001). The median (Q1, Q2) was 20 (15, 28) at initial visit and 20 (15, 25) at follow-up.

N = patients with at least 6 months of follow-up.

Mean duration of follow-up was 67.1 months.

The standard box plots reflect the median and the 25th and 75th quartiles.

Improvement in Quality of Life in Surgically Treated Adult Epilepsy Patients (N = 599)

2007 – 2021

QOLIE-10 = Quality of Life in Epilepsy questionnaire

In surgically treated patients, the mean QOLIE-10 score improved from 27.8 at initial visit to 23.1 at last follow-up (P < 0.001). The median (Q1, Q2) was 27 (21, 35) at initial visit and 22 (17, 29) at follow-up.

N = patients with at least 6 months of follow-up.

Mean duration of follow-up was 44.3 months.

The standard box plots reflect the median and the 25th and 75th quartiles.

Clinically Meaningful Improvement in Quality of Life

2007 – 2021

Patients Achieving Clinically Meaningful Improvement
Medically treated patients (N = 3664)39.9%
Surgically treated patients (N = 599)56.7%

Clinically meaningful improvement in quality of life is defined as a drop of at least 10% in the baseline QOLIE-10 Score.¹

References
  1. Cramer JA, Perrine K, Devinsky O, et al. A Brief Questionnaire to Screen for Quality of Life in Epilepsy The QOLIE-10. Epilepsia 1996;37(6):577-582