Allergy and Clinical Immunology

Allergic and immunologic disorders, including asthma, have become much more common. Allergies now affect an estimated 50 million Americans.

Our Department of Allergy and Clinical Immunology is one of the largest in the United States, and is committed to excellence in patient care, research, education and advocacy. We offer comprehensive and evidence-based diagnosis and management for adults and children with conditions within the spectrum of allergic/immunology disorders, including asthma, food allergy, atopic dermatitis (eczema), year-round and seasonal allergic rhinitis (hay fever), anaphylaxis, sinusitis, angioedema (swelling), urticaria (hives), stinging insect allergy, common variable immunodeficiency, aspirin sensitivity syndromes, chronic cough and drug allergy.

Our physicians also have experience in diagnosis and treatment of rare and difficult-to-treat conditions including C1 inhibitor deficiency syndromes, severe asthma, systemic mast cell disorders (e.g. mastocytosis), resistant-to-treat urticaria and complex disorders of the immune system. We offer extensive evaluations that may include skin testing and challenge procedures to rule out or confirm a diagnosis.

For patients with allergic or immunologic disorders, we offer a broad range of treatment options including medications, biologic agents, immunoglobulin replacement, drug desensitization and allergen immunotherapy. 

Services and Treatments
  • Allergy (immediate hypersensitivity) skin testing
  • Allergen immunotherapy (allergy shots)
  • Biologic agents for asthma, chronic urticaria, atopic dermatitis 
  • Drug and food/food additive challenges 
  • Drug desensitization 
  • Intravenous immunoglobulin (IVIg) administration

Make an Appointment

Call 216.444.6503 or 800.223.2273, ext. 46503, or contact us online to make an appointment today.

Our Doctors

Our Doctors

Health Information Research & Clinical Trials

Research & Clinical Trials

Please check back soon for an updated list of clinical trials and research. 

For Medical Professionals

For Medical Professionals


Allergy and Immunology Fellowships

Allergy/immunology training at the Cleveland Clinic fosters the skills to be successful in clinical practice or a career at an academic center. The fellowship includes exposure to a wide range of patients with common and uncommon conditions. Fellows work closely with faculty who are dedicated to fulfilling the educational mission of the Cleveland Clinic, through both immunology and allergy treatments and elective rotation in asthma, dermatology, otolaryngology, pulmonary and critical care, radiology, rheumatology, infectious diseases, and/or other areas. Learn more about our allergy/immunology fellowships.


Cleveland Clinic's Respiratory Institute offers continuing medical education courses through the Center for Continuing Education. We are providers of AMA-approved continuing medical education (CME) units for physicians and physician assistants, and of continuing education units by the Ohio Nurses Association for nurses and by the Ohio Respiratory Care Board for respiratory therapists.

Appointments & Locations

Appointments & Locations

To make an appointment, please call 216.444.6503.

Online Second Opinions

We offer second opinions through Cleveland Clinic MyConsult, an effective and secure option for consultation without the time and expense of travel. One of our experts will review your medical records and test results and provide a comprehensive, personalized report, taking care to answer your specific questions.