Asthma is one of the most common chronic diseases in the world, becoming more prevalent and more severe in recent years. Asthma causes the airways of the lungs (bronchial tubes) to narrow, the lining of the airways to become inflamed and irritated, causing spasms or swelling, and the cells that line the airways to produce more mucus.
These changes make breathing difficult and cause symptoms, such as cough, shortness of breath, wheezing, chest tightness and excess mucus production.
Why choose Cleveland Clinic for asthma care?
At Cleveland Clinic's Asthma Center, we offer the most advanced diagnostic testing and innovative treatments for adults and children with asthma. Within Cleveland Clinic's Respiratory Institute, the Asthma Center brings together physicians from allergy and immunology, pulmonary and critical care, and sports medicine (for asthma in elite athletes).
For those with asthma and co-existing conditions, such as chronic rhinosinusitis, nasal polyps, gastroesophageal reflux, inducible laryngeal obstruction, cataracts, glaucoma or osteoporosis, we also coordinate your care with specialists in gastroenterology, ophthalmology, otolaryngology, osteoporosis and metabolic bone disease, and speech therapy. Our integrated approach to patient care provides you with state-of-the-art diagnostic and treatment services and opportunities to try new medications and therapies through clinical trials.
Our asthma services
We offer a full range of clinical services for asthma care, including:
- Comprehensive consultation services and ongoing care for refractory asthma (poorly-controlled asthma).
- Evaluation for occupational and environmental asthma.
- Specialized testing (Spriometry and Exhaled Nitric Oxide) to determine how well your asthma is being controlled.
- Bronchoprovocation testing, including Methacholine and Mannitol.
- Highly specialized treatment for asthma, including new and innovative therapies from injections to procedures.
- Treatment and help to manage other conditions that complicate asthma control.
- Management plans for newly diagnosed asthma cases and continued care when needed.
Cleveland Clinic's Asthma Center also collaborates with other departments of Cleveland Clinic, including Obstetrics and Gynecology, to educate the public about asthma in pregnancy and the Multicultural Lung Health Center to help address asthma health disparities.
View our treatment outcomes
Our Outcomes offer detailed information and data to help patients and their physicians make informed decisions about treatment for various respiratory issues.
What We Treat
Asthma Symptoms, Causes and Triggers
- Asthma Symptoms
- Asthma Causes and Triggers
- Smoking (vaping) and Asthma
- Exercise-induced Asthma
- Stress and Asthma
- Infection as an Asthma Trigger
Asthma in Special Populations
Novel Diagnostic and Treatment Approaches
Our physicians have particular expertise in refractory asthma or poorly-controlled asthma. For patients with refractory asthma, the Asthma Center offers innovative diagnostic and treatment services that are at the forefront of asthma care including:
- Measurement of inflammatory biomarkers in exhaled breath for patients not responding to therapies, and requiring high doses of corticosteroids
- Bronchoscopic evaluation to identify potential chronic causes of asthma
- Allergen immunotherapy (allergy shots)
- Anti-IgE therapy
- Anti-Interleukin-5 therapies
- Bronchial thermoplasty: a technique designed to reduce the contractility of airway smooth muscle by applying radiofrequency energy to airway walls in selected individuals
- Aspirin desensitization: used to develop tolerance to aspirin and similar drugs for patients with aspirin-exacerbated respiratory disease
Appointments & Locations
To make an appointment, please call 216.444.6503.
Virtual Second Opinions
If you cannot travel to Cleveland Clinic, help is available. You can connect with Cleveland Clinic specialists from any location in the world via a phone, tablet, or computer, eliminating the burden of travel time and other obstacles.
If you’re facing a significant medical condition or treatment such as surgery, this program provides virtual access to a Cleveland Clinic physician who will review the diagnosis and treatment plan.
Following a comprehensive evaluation of medical records and labs, you’ll receive an educational second opinion from an expert in their medical condition covering diagnosis, treatment options or alternatives as well as recommendations regarding future therapeutic considerations. You’ll also have the unique opportunity to speak with the physician expert directly to address questions or concerns.
Find additional information on the following helpful links:
American Lung Association
- Asthma Control Test: Can help you and your healthcare provider determine if your asthma symptoms are well controlled. Sharing your or a family member's score with a healthcare provider may help them determine your treatment.
Asthma Treatment and Management
- Asthma Treatments
- Alternative Therapy for Asthma
- Bronchial Thermoplasty
- Asthma Management
- Traveling with Asthma
- Exercise and Asthma
Using an Inhaler
- How to Use a Peak Flow Meter
- How to Use a Metered Dose Inhaler
- How to Use Your Flexhaler Dry Powder Inhaler
- How to Use Your Diskus Dry Powder Inhaler
- How to Use Your Turbuhaler Dry Powder Inhaler
- Diagnosing Asthma
Research & Clinical Trials
Clinical trials (or research studies) help us create the medicine of tomorrow. They provide hope through offering testing of new drugs, new surgical techniques or other treatments before they are widely available.
We can help you access hundreds of clinical trials across all specialty areas. Our new searchable online trials tool makes identifying treatment opportunities easier than ever.
Recommended Research Readings
View helpful research publications on the topic of asthma below:
- Associations of Air Quality with Asthma During the Cleveland Multiple Air Pollutant Study (CMAPS) -Khatri SB, Newman C, Rose J, Ross K, Pillai M, Holstein A, Tailor S, Hammond S, Norris G. Am J Respir Crit Care Med. 2010; 181:A6827.
- Angioplasticity in Asthma - Asosingh K, Erzurum SC.Biochem Soc Trans. 2009 Aug;37(Pt 4):805-10.
- Association of Ambient Ozone Exposure with Airway Inflammation and Allergy in Adults with Asthma -Khatri SB, Holguin FC, Ryan PB, Mannino DM, Erzurum SC, and Teague WG. J of Asthma 2009; 46: 777-785.
- When Should a Methacholine Challenge Be Ordered for a Patient with Suspected Asthma? - Swartz, E, and Lang, D. Cleveland Clinic Journal of Medicine. 2008: 75(1): 37-40.
- Th1- and Th2- Dependent Endothelial Progenitor Cell Recruitment and Angiogenic Switch in Asthma - Asosingh K, Swaidani S, Aronica M, Erzurum SC. J Immunol. 2007, 178:6482-6494.
- The Pathology of Asthma, with Special Reference to Changes in the Bronchial Mucosa - Dunnill MS. J Clin Pathol. 1960 Jan;13:27- 33.
For Medical Professionals
Following a patient evaluation at the Asthma Center, our team provides a timely, specialized report that includes our evaluation, test results and a proposed plan of care. Our specialists may assume care for patients or provide a treatment plan to you and the patient to carry out proposed recommendations.
Our secure online service, Dr.Connect, provides referring physicians access to patient’s treatment progress with streamlined communication from Cleveland Clinic physicians to your office, allowing continued participation in the ongoing care of patients. With the best possible treatment plans and coordinated care, our team approach benefits both the patient and the referring physician.
To refer a patient, call the Asthma Center at 216.444.0582 or the Bronchial Thermoplasty Referral Line at 216.445.6266.
- Learn more about physician referrals to the Cleveland Clinic Respiratory Institute
Allergy and Clinical Immunology Fellowships
Cleveland Clinic Respiratory Institute offers two fellowships in allergy/immunology each year. Fellows will gain experience working in a multi-specialty group practice setting, with a busy outpatient allergy/immunology practice and have the opportunity to do elective rotations in asthma, dermatology, otolaryngology, pulmonary and critical care, radiology, rheumatology, infectious diseases, and more.
Pulmonary and Critical Care Medicine Fellowships
Our pulmonary and critical care medicine fellowships provide board-certified general internists with the tools necessary to care for patients, who have complicated lung diseases and critical illnesses. During the three-year training period, which includes an 18-month core program and 18-month subspecialty track, fellows are exposed to a wide variety of medical problems in both the inpatient and outpatient settings.
The Cleveland Clinic Respiratory Institute offers continuing medical education courses through the Center for Continuing Education. Current CME offerings include:
Disease Management Project
Cleveland Clinic publishes an online medical reference, the Disease Management Project, which provides nationally-established treatment guidelines for the most common diseases and conditions