An endarterectomy is a surgical procedure to remove plaque buildup from narrowed or blocked arteries. It may be a treatment for peripheral artery disease or carotid artery disease. Your provider makes an incision over the blocked artery during the procedure. Then, they use a special tool to remove plaque, improving blood flow.
Advertisement
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
An endarterectomy (en-DAR-tuh-RECK-toh-mee) is a surgery to open narrowed or blocked arteries. Your healthcare provider uses the procedure to remove plaque, a fatty and calcified substance that can build up in arteries. Removing this buildup improves blood flow through your arteries and reduces your risk of blood clots or stroke.
Advertisement
Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Providers can use an endarterectomy to treat various forms of atherosclerosis. This is plaque buildup in an artery that eventually leads to stiff, narrowed arteries. Usually, providers use endarterectomies for moderate to severe cases, especially if you have symptoms.
Conditions an endarterectomy procedure treats include peripheral artery disease (PAD) and carotid artery disease.
In PAD, plaque builds up in the arteries in your legs or arms. This blocks blood flow and may lead to pain, wounds and eventual death (gangrene) of your tissues.
Carotid artery disease is plaque buildup in your carotid arteries. These are blood vessels that carry blood to your brain. Narrow carotid arteries can lead to a stroke, transient ischemic attack (TIA) or transient blindness if you don’t get treatment.
The type of endarterectomy procedure you have depends on where you have a blocked artery:
Advertisement
Before an endarterectomy procedure, you’ll likely have tests to evaluate the extent of the artery blockage, including:
Your provider will give you instructions to prepare for an endarterectomy. You may need to stop taking certain medications, like blood thinners (anticoagulants), temporarily. In other cases, your provider may tell you to start taking antiplatelets, like aspirin, before surgery.
You’ll need to fast before an endarterectomy. Your anesthesia team will tell you how long to fast before the operation.
You may also have tests to assess your overall heart health, like an echocardiogram or stress test. Cardiovascular tests help your provider evaluate your heart attack risk and determine if you’re a good candidate for surgery.
Some people have risk factors that mean endarterectomy isn’t a suitable treatment option. You may not be a candidate for an endarterectomy if you have conditions that would make the surgery more dangerous, like:
But a provider may be able to remove blockages through a minimally invasive option called atherectomy. They may be able to treat others with metal scaffolds (stents) to open up the blockages.
You receive anesthesia so you don’t feel any pain during an endarterectomy. Most people will be under general anesthesia and unconscious. But your provider may use regional anesthesia like a spinal block or keep you awake using local anesthesia. The most common procedure providers do with local anesthesia is a carotid endarterectomy to better monitor your brain function.
For a carotid endarterectomy, a provider may place a tube (shunt) to keep blood flowing to your brain during the procedure.
During an endarterectomy, your healthcare provider:
Advertisement
A carotid endarterectomy takes about one or two hours. Times vary for other types of endarterectomies. Factors like the type of anesthesia you get and the medical conditions you have affect how long a procedure takes.
An endarterectomy procedure removes the blockages and restores your artery back to its normal, healthy size. The cleaned-out vessel can help heal leg wounds or resolve leg pain with walking or belly pain from poor circulation. It can also significantly reduce your risk of stroke.
The results of an endarterectomy usually last for many years.
Endarterectomies are typically safe, but there’s a risk of complications like:
In most people, the risk of serious complications is low. It depends on the location and the reason for the surgery. If your provider recommends an endarterectomy, it means that they believe the benefits outweigh the potential risks.
Some factors can increase your risk of experiencing complications after an endarterectomy, including:
Advertisement
You may have a drainage tube extending from the incision site immediately after surgery to keep the area from bruising. Your provider will remove this before releasing you to go home. They’ll keep an eye on your vital signs as you recover.
You’ll likely be allowed to drink and eat a few hours after your procedure unless you have an incision in your abdomen. You may have some numbness or pain around the area where the provider cut into your skin.
Your provider may prescribe antiplatelets or anticoagulants for you. You may take these for several months after your surgery. If you have a pulmonary endarterectomy, you’ll take these blood thinners for the rest of your life.
The length of your hospital stay will depend on the type of surgery and location. You may need to stay in the hospital for:
You’ll have a follow-up visit with your healthcare provider about four weeks after the endarterectomy. Your provider will examine the incision and image the repair over time with ultrasonography or CT scans. Most people can return to work after this follow-up visit. You may need at least six weeks to recover after an aortic, visceral or pulmonary endarterectomy.
Advertisement
Physical activity can help recovery, but it’s important to avoid strenuous activity until your provider tells you it’s OK. You may need to wait one or two months to return to work if you have a job that requires manual labor or strenuous physical activity. For aortic or visceral endarterectomy, you won’t be able to lift more than 10 pounds for two months until the abdominal area has healed and strengthened.
If you have stitches, a provider will need to remove them at a follow-up visit. If you had an endarterectomy in your leg, a provider may check your ankle-brachial index (ABI) every six months.
This will depend on the area of your body that had the endarterectomy. The biggest risk is heart-related issues like heart attack down the road. But risk prediction methods don’t consider every factor. Everyone is different. Your healthcare provider is the best person to talk to you about your life expectancy.
Call your provider right away if you have any signs of complication after an endarterectomy, including:
Both are procedures to improve blood flow in blood vessels. Healthcare providers can use an endarterectomy to remove plaque or (in rare cases) blood clots. A thrombectomy is only for removing blood clots.
No. In an endarterectomy, a provider surgically pulls plaque out of your artery. With angioplasty, a provider pushes plaque against the sides of your artery wall. Sometimes, they may destroy the plaque with a laser. Also, an angioplasty is a minimally invasive procedure.
No. Although both remove plaque, they do it differently. An atherectomy is a minimally invasive procedure. An endarterectomy is a surgical procedure that involves cutting directly into your artery.
In an atherectomy, a provider guides a catheter through your artery. When the catheter reaches the narrow or blocked section, a provider uses a tool at the end of the catheter to remove the plaque.
An endarterectomy is an open surgery, meaning it’s a major operation. You may stay in the hospital for one or several days, and recovery takes several weeks to months. But complications of a carotid or femoral endarterectomy are uncommon. People usually tolerate aortic and iliac endarterectomy well and have infrequent major complications.
Most people have long-lasting positive results from an endarterectomy.
For most people, having surgery isn’t an everyday thing. It’s normal to have questions and concerns. But if your provider recommended an endarterectomy, they believe it will benefit you. And because they do these surgeries every day, they can answer the questions you have. Don’t be afraid to ask for more information.
Plaque in your blood vessels can cause tingling, pain and numbness. Cleveland Clinic’s experts treat circulatory problems, including peripheral artery disease.
Last reviewed on 05/14/2025.
Learn more about the Health Library and our editorial process.