Sleep Disorders

Obesity Hypoventilation Syndrome and Bariatric Surgery

Relationship of a Composite Outcome With OaSH Postbariatric Surgery (N = 1665)

2011 – 2018

The relationship of obesity-associated sleep hypoventilation (OaSH) and adverse postoperative outcomes postbariatric surgery was studied. Patients undergoing polysomnography (PSG) prior to bariatric surgery at Cleveland Clinic from 2011 to 2018 were retrospectively examined.

AHI = Apnea-Hypopnea Index, BMI = body mass index, OaSH = obesity-associated sleep hypoventilation

The analytic sample was comprised of 1665 patients: aged 45.2 ± 12 years, 20.4% male, BMI 48.7 ± 9 kg/m², and 63.6% Caucasian. OaSH prevalence was 68.5%. Although some outcomes were respectively higher in OaSH vs non-OaSH, findings for individual outcomes were not statistically significant: intubation (1.5% vs 1.3%, P = 0.81) and 30-day readmission (13.8% vs 11.3%, P = 0.16). The composite outcome was significantly higher in OaSH vs non-OaSH (18.9% vs 14.3%, P = 0.021). The figure shows a multiple logistic regression model of the composite outcome. With adjustment of age, gender, BMI, AHI, and diabetes, the odds of the composite event was 36% higher in OaSH group than non-OaSH group (OR 1.36, 95% CI, 1.00-1.84, P = 0.047).