History, Mission and Vision


The American Center for Reproductive Medicine was founded in 1993 as the research program of the Glickman Urological & Kidney Institute. Our research fellowship, ART training and summer mentorship opportunities represent one of the largest and most comprehensive academic programs of its kind in the United States.


Our mission is to conduct cutting-edge research into the causes of human reproductive and sexual disorders, leading to the development of new treatments and cures, as well as training of physicians and scientists to advance the understanding of human reproduction, infertility and sexual function.


Our vision is to mentor and train each research fellow, trainee and summer intern using an individualized approach, to develop technical expertise and the ability to work independently.


The Cleveland Clinic Andrology Laboratory and Reproductive Tissue Bank is fully accredited by the College of American Pathologists' Reproductive Laboratory Accreditation Program.


Scholarship in Teaching Award for the Training Program in Advanced Reproductive Techniques

The Case Western Reserve School of Medicine Scholarship in Teaching Awards is an annual program designed to recognize faculty contribution to education from the preceding year and promote undergraduate, graduate, and continuing medical education teaching as a scholarly activity.


The Center conducts basic science and translational research into oxidative stress, proteomics and male infertility.

For an up to date list of our publications, visit Dr. Agarwal's profile.

A Web of Science Citation Report of Research Publications by the American Center for Reproductive Medicine from 1993 to 2013 is available here.



Ashok Agarwal, PhD

Ashok Agarwal, PhD
Director of the Clinical Andrology Laboratory and Sperm Bank

Rakesh Sharma, PhD

Rakesh Sharma, PhD
Assistant Technical Supervisor
Andrology Center and Reproductive Tissue Bank

 Sajal Gupta, MBBS, MS, TS (ABB)

Sajal Gupta, MBBS, MS, TS (ABB)
Andrology Center and Reproductive Tissue Bank

Dr. Gupta is an Assistant Professor in the Cleveland Clinic Lerner College of Medicine and the Technical Supervisor of Andrology Laboratory and Reproductive Tissue Bank. She has done her residency in Ob-Gyn from the University of Delhi and then completed two Fellowships in Reproductive Medicine: a WHO Fellowship, followed by a Research Fellowship at the Cleveland Clinic. She received a Masters in Clinical Embryology and Andrology from the Eastern Virginia Medical School. She is a recipient of several awards during her tenure in the Andrology Lab such as the Tommaso Falcone Award for Excellence in Female Infertility Research, Scholarship in Teaching Award by Case Western Reserve Medical School and Innovator Award. Dr. Gupta has published over 90 research articles in peer-reviewed scientific journals, and authored a dozen book chapters. As the Technical Supervisor of the Andrology Lab since last 13 years, Sajal is responsible for the day to day operation of Andrology Laboratories in two Cleveland location. She manages the work-flow, address any patient related problems, triages with referring physician, updates Andrology SOP and conducts competency assessment. She is responsible for the Andrology Lab Quality management, safety compliance and annual re-accreditation of Andrology laboratory through various agencies such as CAP, ODH, FDA and JCAHO. Alongside her supervisory duties, Sajal loves to work on the bench and takes care of patients coming for a variety of tests and services. She is a compassionate and dedicated professional who has trained scores of individuals in Andrology tests.

Invited Trainers, Clinical Embryologists

Christina Anagnostopoulou, MS  | Cleveland Clinic 

Christina Anagnostopoulou, MS

Christina Anagnostopoulou has studied Biology at the National University of Athens and was trained as a clinical embryologist in Aberdeen Maternity Hospital and Cleveland Clinic. She has been working in the field of assisted reproduction since 2004 and currently she is employed as a senior clinical embryologist at the ART unit AKESO-EMBRYO ART which is situated in Athens, Greece.

Since 2011 she has been providing IVF training at the American Center for Reproductive Medicine at Cleveland Clinic as visiting faculty. She is actively engaged in the theoretical part of the course by delivering lectures and in the practical part by demonstrating techniques such as oocyte denudation, ICSI, vitrification and embryo biopsy.

Israel Maldonado Ross, MS | Cleveland Clinic 

Israel Maldonado Rosas, MS

Dr. Israel Maldonado Rosas is the owner and CEO of the IVF Clinic “CITMER with branches in three Mexican cities. He was trained as a Clinical Embryologist at the Instituto Valenciano de Infertilidad at Valencia, Spain and received additional training at the Kato Ladies Clinic in Japan. In 2020, Israel was recognized as the Embryologist of the Month by the American College of Embryology (ACE). He serves as a Visiting Faculty in the ART Training Program of the American Center for Reproductive Medicine at Cleveland Clinic.



Module: 1
Course: Semenology
Duration: 40 hours (1 week)
Fees: USD 5,295

Module: 1A
Course: Routine Semen Analysis
Duration: 8 hours (1 day)
Fees: USD 950

Module: 1B
Course: Sperm Morphology
Duration: 16 hours (2 days)
Fees: USD 1,395

Module: 2A
Course: Advanced Andrology Techniques
Duration: 40 hours (5 days)
Fees: USD 5,750

Module: 2B
Course: Advanced Andrology Techniques
Duration: 80 hours (10 days)
Fees: USD 10,500

Module: 3
Course: ART Sperm Preparation
Duration: 16 hours (2 days)
Fees: USD 2,250

Module: 4
Course: Cryopreservation Techniques
Duration: 8 hours (1 day)
Fees: USD 1,950

Module: 5A
Course: IVF / ICSI / Micromanipulation
Duration: 80 hours (2 weeks)
Fees: USD 7,950

Module: 5B
Course: ICSI / Micromanipulation
Duration: 40 hours (1 week)
Fees: USD 6,200

Module: 5C Course: Advanced ART Techniques
Duration: 40 hours (1 week)
Fees: USD 6,850

Module: 5D
Course: Customized ART Training
Duration: Selected by Trainee
Fees: To Be Determined

Module: 6
Course: Vitrification
Duration: 8 hours (1 day)
Fees: USD 2,500

Module: 7
Course: Management of IVF and Andrology Labs
Duration: 16 hours (2 days)
Fees: USD 2,800

Module: 8
Course: Preparing for CAP Accreditation and FDA Inspection
Duration: 16 hours (2 days)
Fees: USD 2,800

Module: 9
Course: Training in Scientific Writing
Duration: 120 hours (15 days)
Fees: USD 10,500

Module: 10
Course: Training in Bench Research
Duration: 160 hours (20 days)
Fees: USD 15,000


  • Acquire a basic understanding of assisted reproductive techniques
  • Acquire the skills in the use of a micromanipulator
  • Impact hands-on training in intracytoplasmic sperm injection
  • Acquire skills in various assisted reproductive procedures
  • Observe aspiration and retrieval of oocytes
  • Participate actively in interactive sessions/lectures

General Teaching and Learning Methods:

  1. Fully hands-on, one-to-one laboratory training sessions will be provided under the direct tutelage of 2 highly-competent and practicing Clinical Embryologists
    * Module 5 involves training using animal models (frozen hamster oocyte and mouse embryos)
  2. Other Trainers include Andrologists, Reproductive Endocrinologists and other invited ART experts
  3. Each training session is customized to the Trainee's
    1. Professional background
    2. Level of skill and competence
    3. Specific training needs
    4. Desired outcomes obtained from attending the ART training course
  4. Interactive discussion and teaching sessions
  5. Live lectures and multimedia presentations in small group sessions

Four state-of-the-art micromanipulators dedicated solely for training purposes (IVF/ICSI)

Assessment Methods:

Aspects of the Training that will be assessed include:

  1. Knowledge: There will be a summative test comprising multiple choice questions on the practical and theoretical aspects of the ART for each module
  2. Practical Skills: Each Trainee will be individually tested for competency on specific laboratory techniques learnt during the module
  3. Presentation and Communication Skills: Each Trainee will be required to give a talk (oral with and without the aid of slides) during the course of the module

What Each Trainee Will Receive:

  1. Course Syllabus with Reading Material and Lab Protocols
  2. Free Access to the Cleveland Clinic Alumni Library
  3. Free Text Book on “Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices” edited by Dr. Peter Nagy et al, Springer. Available to candidates who register for either Module 5A, 5B, 5C or 5D
  4. WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 5th Edition (digital file)
  5. Certificate of Training (issued upon successful assessment by the instructor)
  6. Daily Meal Tickets
How to Apply

How to Apply

Application Deadline

* July 30th (for training: September 3 - September 30, 2022)

* Notes:

  • Deadline is only for Modules 5A, B, C, D and 6
  • Candidates can apply throughout the year for:
    Modules 1, 1A, 1B, 2, 3, 4, 7, 8, 9 & 10
  • Candidates can choose additional modules during training from the beginning of September to the end of October

Who Can Apply

Clinicians, biologists and scientists with a background and interest in the field of Embryology, Reproductive Medicine, and Andrology are eligible.

Who to Contact

Dr. Ashok Agarwal
Program Director
Assisted Reproduction Training (ART)

American Center for Reproductive Medicine
Cleveland Clinic
10681 Carnegie Avenue, X11
Cleveland, OH 44195, USA

Tel: 216.444.9485
Fax: 216.445.6049
E-mail: [email protected]

Please Note: Except for Modules 5 and 6, candidates can schedule their training in all remaining modules year round.
Document Submissions

Submit your supporting documents by attaching them to this form. Documents are not encrypted. However, they are saved in a controlled access program utilized by program contacts only. Your application must be submitted with all supporting documents attached.

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Terms & Conditions

Applicant acknowledges the following requirements for application for training:

  • Fee is payable in full in the form of a money order or certified bank check as instructed. Please refer to the
    “How to Apply” section for details.
  • In order to complete the application please send the application fee to the program address shown in the
    “Who to Contact" section.
  • Please note that there is no discount for multiple training modules (eg. Modules 1, 2, 3 = $11,150.00 (USD)
    and will last 2 weeks).
  • Request for refunds of 50% of course fees may be allowed if requests are received in writing up to 4 weeks
    prior to the scheduled training. No refunds will be issued if made after that time.