Cognitive Disorders

Quality of Life

Change in Quality of Life (Mental Health) in Patients With Cognitive Disorders (N = 32)

2020 Center for Brain Health, PROMIS Mental Health

AD = Alzheimer disease, FTD = frontotemporal dementia, LBD = Lewy body dementia, MCI = mild cognitive impairment

ᵃNumbers in this category do not add up to 100% due to rounding.

Fluctuations in 2020 volumes are a result of significant changes to the number of patients treated, which can be directly attributed to the COVID-19 pandemic.

Quality of mental health, as measured by PROMIS Mental Health,¹ remained stable or improved in most patients with a baseline score of ≤ 45, despite stable or declining cognition. Clinically meaningful change was defined as at least a 5-point change in T-score, based on one-half the standard deviation.²

Change in Quality of Life (Physical Health) in Patients With Cognitive Disorders (N = 26)

2020 Center for Brain Health, PROMIS Physical Health

AD = Alzheimer disease, FTD = frontotemporal dementia, LBD = Lewy body dementia, MCI = mild cognitive impairment

Fluctuations in 2020 volumes are a result of significant changes to the number of patients treated, which can be directly attributed to the COVID-19 pandemic.

Quality of physical health, as measured by PROMIS Physical Health,¹ remained stable or improved in most patients with a baseline score of ≤ 45, despite stable or declining cognition. Clinically meaningful change was defined as at least a 5-point change in T-score, based on one-half the standard deviation.²

References
  1. Hays RD, Bjorner JB, Revicki DA, Spritzer KL, Cella D. Development of physical and mental health summary scores from the patient-reported outcomes measurement information system (PROMIS) global items. Qual Life Res. 2009 Sep;18(7):873-880.
  2. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care. 2003 May;41(5):582-592.