Cognitive Disorders

Quality of Life

Change in Quality of Life (Mental Health) in Patients With Cognitive Disorders

2023 Center for Brain Health, PROMIS Mental Health

AD = Alzheimer disease, FTD = frontotemporal dementia, LBD = Lewy body dementia, MCI = mild cognitive impairment

Quality of mental health, as measured by PROMIS Mental Health,¹ remained stable or improved in most patients with a baseline score of ≤ 45, despite stable or declining cognition. Clinically meaningful change was defined as at least a 5-point change in T-score, based on one-half the standard deviation.¹

Change in Quality of Life (Physical Health) in Patients With Cognitive Disorders

2023 Center for Brain Health, PROMIS Physical Health

AD = Alzheimer disease, FTD = frontotemporal dementia, LBD = Lewy body dementia, MCI = mild cognitive impairment

Quality of physical health, as measured by PROMIS Physical Health,¹ remained stable or improved in most patients with a baseline score of ≤ 45, despite stable or declining cognition. Clinically meaningful change was defined as at least a 5-point change in T-score, based on one-half the standard deviation.¹

References
  1. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care. 2003 May;41(5):582-592.