Episodic Migraine

Outcomes of Treatment in Episodic Migraine Patients (N = 282)

2017 – 2018

HIT-6 = Headache Impact Test, PDI = Pain Disability Index, PHQ-9 = Patient Health Questionnaire, PROMIS = Patient Reported Outcome Measurement Information System

In 2017 and 2018, 282 patients with episodic migraine and a follow-up visit were reviewed. The median interval between initial appointment and follow-up was 185 days (range, 141–585). Of the 72 patients who reported HIT-6 scores > 50 at initial evaluation, 29% reported improvement at their second visit.¹ Of the 101 patients who reported initial PDI scores ≥ 20, 34% reported improvement at their second visit.² Of the 81 patients who reported initial PROMIS pain at or above the median score of 6, 100% improved or remained stable. Of the 64 patients who completed the PHQ-9 at 2 visits and reported initial depressive symptoms ≥ 10 points, 33% reported improvement depressive symptoms on follow-up. Overall, approximately 80% of patients reported improved or stable symptoms for all 4 reported measurements.

  1. Coeytaux RR, Kaufman JS, Chao R, Mann JD, Devellis RF. Four methods of estimating the minimal important difference score were compared to establish a clinically significant change in Headache Impact Test. J Clin Epidemiol. 2006 Apr;59(4):374-380.
  2. Soer R, Reneman MF, Vroomen PC, Stegeman P, Coppes MH. Responsiveness and minimally clinically important change of the Pain Disability Index in patients with chronic back pain. Spine, 2012 Apr 15;37(8):711-715.
  3. Hays RD, Bjorner JB, Revicki DA, Spritzer KL, Cella D. Development of physical and mental health summary scores from the patient-reported outcomes measurement information system (PROMIS) global items. Qual Life Res. 2009 Sep;18(7):873-880.
  4. Löwe B, Unützer J, Callahan CM, Perkins AJ, Kroenke K. Monitoring depression treatment outcomes with the Patient Health Questionnaire-9. Med Care. 2004 Dec;42(12):1194-1201.