Chronic Migraine

Chronic migraine refers to migraine headaches occurring at least 15 days per month, frequently associated with significant functional impairment and depression.

Outcomes of Treatment in Chronic Migraine Patients (N = 3026)


HIT-6 = Headache Impact Test, PHQ-9 = Patient Health Questionnaire, PROMIS = Patient Reported Outcome Measurement Information System

In 2021, 3026 patients with chronic migraine completed at least 1 questionnaire following treatment, with a median interval between initial appointment and follow-up of 189 days (range, 7-651). Of the 2342 patients who reported HIT-6 scores > 50 at initial evaluation (higher scores indicate greater impairment secondary to headache pain¹), 74% improved or remained stable. Of the 1214 patients who reported initial PROMIS² pain at or above the median score of 6, 88% improved or remained stable. Of the 932 patients who reported initial depressive symptoms ≥ 10 points for the PHQ-9 (higher scores indicate greater depression³), 30% reported improvement at follow-up.

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