Psychiatric Disease

Outpatient Treatment for Mood and Anxiety Disorders

Improvement in Depressive Symptoms and Global Health-Related Quality of Life Among Adult Outpatients

2023

PHQ-9 = Patient Health Questionnaire, PROMIS = Patient-Reported Outcomes Measurement Information System

PHQ-9 Scores

A total of 17,022 patients had at least two visits in 2023 with PHQ-9 data available for analysis. Among those patients whose baseline PHQ-9 score ≥ 10 (N = 6613), 42.8% (N = 2830) showed improvement, 50% (N = 3306) remained stable and 7.2% (N = 477) worsened. Median duration of follow-up was 204 days (range, 1-360 days). Clinically meaningful change was defined as a total point change of 5.¹

PROMIS-10 Mental Health Scores

There were 9420 patients with at least 2 visits in 2023 with PROMIS-10 Mental Health data available for analysis. Among those patients whose baseline PROMIS-10 Mental Health score ≤ 45 (N = 6437), 27% (N = 1739) showed improvement, 62.1% (N = 3996) remained stable, and 10.9% (N = 702) worsened. Median duration of follow-up was 224 days (range, 1-360 days). Clinically meaningful change was defined as a 5-point change in T-score, based on one-half the standard deviation.²

PROMIS-10 Physical Health Scores

9373 patients had at least 2 visits in 2023 with PROMIS-10 Physical Health data available for analysis. Among those patients whose baseline PROMIS-10 Physical Health score ≤ 45 (N = 4729), 30% (N = 1419) showed improvement, 58.3% (N = 2756) remained stable, and 11.7% (N = 554) worsened. Median duration of follow-up was 227 days (range, 1-360 days). Clinically meaningful change was defined as a 5-point change in T-score, based on one-half the standard deviation.²

References
  1. Löwe B, Unützer J, Callahan CM, Perkins AJ, Kroenke K. Monitoring depression treatment outcomes with the Patient Health Questionnaire-9. Med Care. 2004 Dec;42(12):1194-1201.
  2. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care. 2003 May;41(5):582-592.