Psychiatric Disease

Outpatient Treatment for Mood and Anxiety Disorders

Improvement in Depressive Symptoms and Global Health-Related Quality of Life Among Adult Outpatients

2022

PHQ-9 = Patient Health Questionnaire, PROMIS = Patient-Reported Outcomes Measurement Information System

PHQ-9 Scores

A total of 12,153 patients had at least two visits in 2022 with PHQ-9 data available for analysis. Among those patients whose baseline PHQ-9 score ≥ 10 (N = 4963), 43.7% (N = 2169) showed improvement, 49.6% (N = 2462) remained stable and 6.7% (N = 332) worsened. Median duration of follow-up was 189 days (range, 1-361 days). Clinically meaningful change was defined as a total point change of 5.¹

PROMIS-10 Mental Health Scores

There were 9110 patients with at least 2 visits in 2022 with PROMIS-10 Mental Health data available for analysis. Among those patients whose baseline PROMIS-10 Mental Health score ≤ 45 (N = 6460), 30.6% (N = 1974) showed improvement, 59.6% (N = 3851) remained stable, and 9.8% (N = 635) worsened. Median duration of follow-up was 226 days (range, 1-359 days). Clinically meaningful change was defined as a 5-point change in T-score, based on one-half the standard deviation.²

PROMIS-10 Physical Health Scores

9113 patients had at least 2 visits in 2022 with PROMIS-10 Physical Health data available for analysis. Among those patients whose baseline PROMIS-10 Physical Health score ≤ 45 (N = 4922), 30.6% (N = 1507) showed improvement, 58.8% (N = 2892) remained stable, and 10.6% (N = 523) worsened. Median duration of follow-up was 232 days (range, 1-359 days). Clinically meaningful change was defined as a 5-point change in T-score, based on one-half the standard deviation.²

References
  1. Löwe B, Unützer J, Callahan CM, Perkins AJ, Kroenke K. Monitoring depression treatment outcomes with the Patient Health Questionnaire-9. Med Care. 2004 Dec;42(12):1194-1201.
  2. Norman GR, Sloan JA, Wyrwich KW. Interpretation of changes in health-related quality of life: the remarkable universality of half a standard deviation. Med Care. 2003 May;41(5):582-592.