Neurological Institute Outcomes

The graph illustrates the percentage of patients who improved, worsened, or were stable approximately 1 year after acute stroke. Analysis was restricted to patients who had abnormal scores at baseline. Meaningful change was defined as a 5-point change in score for all scales.¹

Global mental and physical health, physical function, anxiety, pain interference, and social role satisfaction were measured by the PROMIS set of measures. Patients with a score of ≤ 45 (significantly lower than population normal) were followed. Change was defined as ≥ 5 point difference between measurements (one-half standard deviation). Depression was measured by the Patient Health Questionnaire, a self-reporting measure of depression. Only those with depression at early assessment (score ≥ 10 points) were included in analysis. A change of ≥ 5 points was deemed a meaningful change.