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Learning you have a blood clotting disorder can make you feel like your body is turning against you. Your blood normally clots to heal you. Why is it doing the opposite?

Maybe you just found out you have a blood clotting disorder after treatment for deep vein thrombosis (DVT). Or maybe you haven’t been diagnosed, but blood clots run in your family. And you’re worried they could happen to you. You might be wondering if you need some tests to see if you’re at risk.

The experts at Cleveland Clinic are here for you whether you already have a diagnosis or are on the path toward one. We can run specialized tests to find blood clotting disorders if you’re at risk for them. We can also develop a plan to lower your risk of complications from abnormal clotting or quickly treat any clots that form. We’ll take some of the mystery out of the condition so you understand what’s happening inside your body, why it’s happening and how we can keep you healthy.

Why Choose Cleveland Clinic for Blood Clotting Disorder Care?

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National recognition:

Cleveland Clinic is nationally ranked for its heart care and recognized as the world leader in cardiovascular care.

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Demonstrated expertise:

Patients travel from all 50 states and around the world to get heart and vascular treatment at Cleveland Clinic due our excellent outcomes.

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High-volume specialty

Cleveland Clinic has one of the largest cardiovascular programs in the country. Our vascular medicine providers have diagnosed and managed the most common blood clotting disorders, as well as the rarest.

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Specialized knowledge:

A blood clot in the lungs is a life-threatening complication of a blood clotting disorder. Our industry-leading pulmonary embolism response team provides fast, life-saving care and long-term treatment plans for this medical emergency.

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Comprehensive treatment:

Blood clotting disorders have a wide range of causes and can affect many different parts of your body. You may also have underlying or associated conditions. We bring together experts from many different specialties to diagnose what’s happening and personalize your care. Meet our team.

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Virtual visits:

Sometimes a virtual visit can solve a problem or answer your questions. You’ll get the same excellent care without leaving home. Just log online and connect with your provider on your smartphone, computer or tablet.

Diagnosing Blood Clotting Disorders at Cleveland Clinic

A blood clotting disorder (also called a hypercoagulable state or thrombophilia) makes your blood form clots too easily and sometimes when it shouldn’t. This means blood clots can form in your veins or arteries and possibly travel through your bloodstream, leading to problems like pulmonary embolism (PE), heart attack and stroke.

At Cleveland Clinic, we know how serious blood clotting disorders can be and we’re dedicated to reducing the impact of these conditions on your life. We diagnose and treat a wide range of blood clotting disorders, including those you’re born with (inherited) and those you develop later on (acquired).

Types of blood clotting disorders

There are many types of blood clotting disorders. Some are inherited, like:

And some are acquired, like:

You can also develop other acquired blood clotting disorders from:

  • Oral contraceptives or hormone replacement therapy.
  • Certain medical conditions, like cancer.
  • Not being able to move your body for long periods of time.

What to expect at your first visit

This is our chance to get to know you and find out what brought you here. We’ll spend some time talking about your medical history, including any conditions you have and whether you’ve had blood clots in the past. We’ll also want to know if any of your biological family members have a history of blood clots. Some types of blood clotting disorders run in families, so this information can help us learn more about your risk.

Then, we’ll do a physical exam to check your vital signs and learn more about your overall health. We’ll also decide which tests you might need to help us make a diagnosis. Possible tests include:

  • Blood tests. Blood tests help us diagnose or rule out certain blood clotting disorders. Many different components of your blood provide clues. For example, we can check the levels of certain proteins (like fibrinogen) that make your blood clot. Higher-than-normal levels of fibrinogen may point to a blood clotting disorder.
  • Genetic testing. In addition to looking at the tiny parts of your blood that make it clot, we may look for changes in your genes, chromosomes and proteins. Some changes can show if you have an inherited condition that makes your blood more likely to clot.
  • Imaging tests. If we need to get a closer look at specific areas inside your body, we’ll do tests like X-rays, ultrasounds or CT scans.

We’ll use all the information we gather to diagnose or rule out specific blood clotting disorders. Depending on what we find, we’ll create a treatment plan tailored to your needs.

Meet Our Blood Clotting Disorders Team

Your Cleveland Clinic team will include experts from many different specialties, all working together to make sure you get outstanding care. Your team may include:


Our healthcare providers see patients at convenient locations throughout Northeast Ohio and London.

Treating Blood Clotting Disorders at Cleveland Clinic

Finding out you have a blood clotting disorder can be unnerving. But rest assured, our specialists are ready to dive in and take the necessary steps to keep you healthy.

The best treatment plan for you depends on your current situation. For example, we’ll take a different approach for someone who has blood clots in their body versus someone who has a blood clotting disorder but no active clots. Possible treatments include:

  • Medications. Anticoagulants are medications that prevent your blood from clotting too easily. We may prescribe them for you to take at home, or we may give them to you through an IV (in a vein in your arm) or injection in the hospital.
  • Thrombolytic therapy. We use “clot-busting drugs” to dissolve clots in certain emergency situations.
  • Compression therapy. Gentle pressure (compression) on certain parts of your body, like your legs, can improve symptoms of deep vein thrombosis (DVT) or prevent new blood clots from forming. For example, we might recommend you wear compression stockings at home. Or, we might use a compression device when you’re in the hospital to prevent DVT.
  • Vena cava filter placement. If you can’t safely take anticoagulants or these medications aren’t doing enough to help, you may need a procedure to put in a vena cava filter. This is a small metal device that prevents blood clots from reaching your lungs.
  • Blood clot removal (embolectomy). We can remove blood clots that moved to various parts of your body, including your lungs. We’ll use traditional surgery or catheter-based methods depending on the size of the clot. Usually, embolectomy is a last resort when medications aren’t helping, or you can’t take them for some reason.

If you haven’t had a blood clot before and don’t have one at this time, you may not need medications or other treatments right now. Instead, we’ll talk about what you can do to prevent a clot from developing. Together, we’ll come up with a plan to help you:

  • Add more exercise to your daily routine.
  • Reach and keep a weight that’s healthy for you.
  • Avoid tobacco products.
  • Lower your risk of blood clots during long flights or road trips.

Taking the Next Step

It’s normal to worry what the future will bring and how a blood clotting disorder might impact your life. There are plenty of unknowns with any condition, but one thing is certain. We’re ready to give you the best possible care. Let our team guide you forward as you get answers to your questions and learn more about what’s going on inside your body. Through it all, we’ll be by your side.

Getting an appointment with Cleveland Clinic’s experts in blood clotting disorders is easy. We’ll help you get the care you need.


Getting an appointment with Cleveland Clinic’s experts in blood clotting disorders is easy. We’ll help you get the care you need.

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