Nationally ranked among the top pediatric gastroenterology programs in the country by U.S. News & World Report, our team of pediatric gastroenterologists and hepatologists care for children with problems of the gastrointestinal tract. We take care of children with a variety of gastroenterological conditions involving organs in the digestive system, including the esophagus, stomach, large bowel, small bowel, liver, gallbladder and pancreas.

Patient visits to the Pediatric Gastroenterology & Hepatology department number more than 10,000 per year. We are also one of the largest U.S. centers for pediatric inflammatory bowel disease.

We see children on Cleveland Clinic's main campus in the Crile Building on the 11th floor (A111) as well as at a number of our family health centers and community hospitals. In collaboration with MetroHealth Medical Center, we also see patients at their main campus, 2500 MetroHealth Drive, Cleveland.

Additional valuable resources for families:

Our gastroenterology program is consistently ranked by U.S. News & World Report's as one of the “Best Children’s Hospitals.” 

Multidisciplinary approach to pediatric gastroenterology and hepatology

  • Our gastroenterological patients have access to multiple specialties including pediatric surgery, pediatric radiology and pediatric anesthesia, as well as the full resources of the Cleveland Clinic.
  • Taking the time to explain treatment options and plans to children and their families is a high priority for our pediatric gastroenterology and hepatology team.
  • Pediatric gastroenterology and hepatology team members also encourage patients and families to actively participate in decision-making over the course of care.
  • Our Pediatric Endoscopy suite and Infusion Center features a new generation of high-definition endoscopes and monitors that permit direct visualization of the various digestive pathways. This superior visualization results in better detection of abnormalities.
  • Our team actively collaborates with other pediatric subspecialty providers in the treatment of pediatric obesity and its associated metabolic complications.
  • We offer specialized evaluations for children with conditions such as cyclic vomiting syndrome, myelomeningocele (spinal problem), feeding problems and children with GI problems associated with airway and lung disease. 

Specialized Gastroenterological Testing

  • We offer some of the most sophisticated and specialized tests needed to diagnose gastrointestinal problems.
  • In addition to diagnostic and therapeutic endoscopy we routinely perform wireless capsule endoscopy and advanced motility procedures with high resolution equipment including esophageal motility, antro-duodenal motility, rectal motility and colonic motility.

Innovative Gastroenterological Treatments

  • Our staff’s involvement in research has included research on new medications that dramatically improve the health of children with moderate to severe pediatric inflammatory bowel disease.
  • Our unique Center for Functional and GI Motility Disorders is able to perform sophisticated motility testing not available at most children's hospitals.
  • Our pediatric psychology and pain therapy team help children with chronic disease learn to cope with pain and other symptoms through biofeedback and other techniques.
  • Pediatric liver transplantation, including living related transplantation and reduced size grafts, provide options for children with very serious liver disease and has excellent survival rates.
  • Small bowel transplantation can help restore intestinal function to those patients whose intestines do not absorb nutrients properly due to disease, injury or prior surgery. This is a new surgical technique and the members of the department can evaluate pediatric patients to see if they may be candidates for this procedure. In addition department members help to manage the complicated nutritional requirements of children with “short gut syndrome”, who one day may need a surgical procedure such as a bowel lengthening procedure or a small bowel transplant.
What We Treat

What We Treat

Digestive disorders in children range from minor to life threatening, and short- to long-term or chronic. Following are just some of the pediatric gastrointestinal conditions we treat and services we provide:



Glycogen Storage Disease (GSD) Program


Glycogen Storage Disease (GSD) is a rare genetic disorder effecting 1 in every 100,000 newborns. The underlying problem in all GSD types is the inability to properly use and or store glycogen as individuals with the disease lack enzymes to store or release glycogen. Treatment and disease management includes assessment of metabolic control through laboratory findings, liver ultrasound, dietary changes, nutritional assessment and monitoring of disease progression and implementation of
appropriate interventions.

Our Team

GSD is managed by a designated multidisciplinary team of pediatric medical professionals and staff at Cleveland Clinic Children’s. The team includes:

  • Physicians (MD or DO)
  • Nurse Practitioner (CNP)
  • Dedicated pediatric GSD Registered Dietician (RD)
  • Vascular access
  • Respiratory Therapy
  • Nursing
  • Nutrition Services

What We Treat

  • GSD Type 0
  • GSD Type I
  • GSD Type III
  • GSD Type IV
  • GSD Type VI
  • GSD Type IX


Please call 216.444.9322 for a consultation.

Pediatric Metabolic Liver Disease Clinic

The Pediatric Metabolic Liver Disease Clinic multi-disciplinary team staff takes a comprehensive approach to preventing the onset and progression of cardiovascular disease and metabolic conditions in high-risk pediatric patients.

Capsule Endoscopy

Capsule endoscopy is an exciting technology that allows our Pediatric Gastroenterologists to look at the entire small bowel tract in a single day. With earlier diagnosis and intervention this test holds promise for lowering morbidity and mortality among adults and children with small bowel problems.

Endoscopy Suite and Infusion Center

New Options for Identifying and Treating Pediatric Digestive Disorders

Cleveland Clinic Children's is providing another level of service to care for the growing population of children with digestive disorders in the new, six bed Pediatric Endoscopy Suite and Infusion Center at Cleveland Clinic's main campus Crile building.

The sophisticated suite, which accommodates more than 750 to 1,000 procedures annually, features a new generation of high-definition endoscopes and monitors that permit direct visualization of the various digestive pathways. This superior visualization results in better detection of abnormalities.

Cleveland Clinic Children's currently serves one of the largest populations of pediatric patients in the United States who suffer from digestive disorders. Our renowned pediatric gastroenterologists are physician specialists who care for children with problems ranging from Colic to Crohn's Disease.



Large, specialized staff

Our 11 board-certified pediatric gastroenterologists subspecialize in areas ranging from fatty liver disease and GI motility disorders to advanced endoscopy and IBD.

Major textbook editors

Former chairman and current Cleveland Clinic Chief Medical Operating Officer Robert Wyllie, MD, is Chief Editor, and current Chair, pediatric endoscopist Marsha Kay, MD, is associate Editor of the textbook Pediatric Gastrointestinal and Liver Disease, now in its 5th Edition (Elsevier).

Liver and Bowel Transplant Expertise

Living-related-donor liver transplants and small bowel transplants are featured in our robust pediatric transplant program.