Overview

Overview

The Lou Ruvo Center for Brain Health in Las Vegas conducts clinical trials to advance new treatments and diagnostic approaches for patients with Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, multiple sclerosis, chronic traumatic encephalopathy, and progressive supranuclear palsy. Since opening in 2009, the center’s clinical trial program has conducted more than 70 studies and enrolled more than 2,500 participants. Both therapeutic (testing new medications) and observational studies are being conducted at the center.

A unique aspect of the Lou Ruvo Center for Brain Health is the capacity to conduct all aspects of a clinical trial in one building. The research department consists of the following

  • Administrative and regulatory support
  • Recruitment specialists
  • 3T MRI
  • Positron Emission Tomography
  • Neuropsychology and rating services
  • On-site laboratory

Contact Information

Alzheimer’s Disease

Marwan Sabbagh, MD
sabbagm@ccf.org

Jeffrey Cummings, MD
cumminj@ccf.org

Aaron Ritter, MDPI
rittera@ccf.org

Parkinson’s Disease

Zoltan Mari
mariz@ccf.org

Odinachi Oguh
oguho@ccf.org

Multiple Sclerosis

Le Hua
hual@ccf.org

Carrie Hersh
hershc@ccf.org

Chronic Traumatic Encephalopathy

Charles Bernick
bernicc@ccf.org

Publications

Publications

Alzheimer's disease drug development pipeline: 2018.  Cummings J, Lee G, Ritter A, Zhong K. Alzheimers Dement (N Y). 2018 May 3;4:195-214. doi: 10.1016/j.trci.2018.03.009. eCollection 2018.

Clinical Trials for Disease-Modifying Therapies in Alzheimer's Disease: A Primer, Lessons Learned, and a Blueprint for the Future. Cummings J, Ritter A, Zhong K. J Alzheimers Dis. 2018;64(s1):S3-S22. doi: 10.3233/JAD-179901.

Why do trials for Alzheimer's disease drugs keep failing? A discontinued drug perspective for 2010-2015. Mehta D1, Jackson R1, Paul G1, Shi J1, Sabbagh M1. Expert Opin Investig Drugs. 2017 Jun;26(6):735-739. doi: 10.1080/13543784.2017.1323868.

Current and Emerging Therapeutics in AD. Sabbagh M1, Decourt B2. Curr Alzheimer Res. 2017;14(4):354-355. doi: 10.2174/156720501404170217182758.

Members & Collaborations

Members & Collaborations

Cleveland Clinic Affiliations