The Section of Invasive and Interventional Cardiology offers cutting-edge diagnostic tests and nonsurgical interventional treatments for patients with atherosclerosis and congenital heart disease. These therapies include the use of stents, angioplasty, intravascular ultrasound, embolic-protection devices and enhanced external counterpulsation (EECP). Our physicians have one of the nation's largest practices for fighting restenosis. Coronary angiography was developed at Cleveland Clinic in 1958 by F. Mason Sones, M.D. The F. Mason Sones Cardiac Catheterization Laboratory features 10 catheterization laboratories. We perform more than 45 catheterizations on a typical day. Our experts are actively involved in research of percutaneous treatments for other heart conditions, including percutaneous valve repair and percutaneous valve replacement surgery.

Each year, the staff of the Section of Invasive and Interventional Cardiology sees thousands of patients with almost every kind of heart disease. Our interventionalists treat people of all ages from around the world who have serious, sometimes life-threatening, cardiac conditions. We provide care for problems as common as a bout of chest pain (angina), as well as more serious conditions such as heart attack (myocardial infarction) and mini-stroke (transient ischemic attack) or as debilitating as leg pain during exercise (severe claudication).

The quality of our care and excellence of our outcomes are well-known and respected in the medical community. Almost half of our patients are referred to us by physicians at other facilities. In many cases, the referring doctors are able to do the procedure themselves, but feel it could be more safely done at Cleveland Clinic. The Section of Invasive and Interventional Cardiology is at the very forefront of innovation in cardiovascular medicine. We often lead clinical trials to study new techniques and devices to restore heart health with catheter-based interventions.


The following is a small selection of current articles from the Section of Invasive and Interventional Cardiology:

What We Treat

What We Treat

The Section of Invasive and Interventional Cardiology offers the latest, most technologically advanced diagnostic tests and catheter based treatments for atherosclerosis, heart valve disease, adult congenital heart disease and peripheral artery disease.

Diagnostic testing includes:

Interventional (catheter based) procedures include:

Additional programs provided include enhanced external counterpulsation (EECP), and stem cell therapy. Our physicians have one of the largest practices in the country for fighting restenosis, the reblockage of previously cleared arteries and important new procedures such as percutaneous aortic valve replacement, high risk procedures such as intervention for blocked left main or single remaining vessel stenosis, and treating difficult to treat blockages (such as bifurcation blockages and total coronary occlusion).

Why choose Cleveland Clinic for your care?

Our outcomes speak for themselves. Please review our facts and figures and if you have any questions don't hesitate to ask.

Cleveland Clinic's Section of Invasive and Interventional Cardiology is a regional and national referral center for catheter based interventions, performing over 11,000 procedures each year.





What to Expect

Whether you are coming from around the corner or around the world, you want to know what to expect before, during and after your visit with us. If you have any questions while reviewing this information, please contact us. We are happy to answer any questions you may have.

By Phone

Call Toll-free 800.223.2273, ext. 46697 or submit an online request.


Go to Desk J2 - 3, 9500 Euclid Avenue, Cleveland, Ohio.


Use our secure online form to submit an appointment request 24/7. We will receive it and follow-up with you as soon as possible.

Physician Referrals

Mon. - Fri., 8 a.m. - 5 p.m. (ET):
toll-free 800.223.2273, ext. 49162



For Patients

Cleveland Clinic Heart and Vascular Institute physicians, surgeons, and researchers continue to research into new treatments and therapies with the goal of improving patient care and outcomes into the future.

Clinical Trials

Clinical trials (or research studies) help us create the medicine of tomorrow. They provide hope through offering testing of new drugs, new surgical techniques or other treatments before they are widely available.

We can help you access hundreds of clinical trials across all specialty areas. Our new searchable online trials tool makes identifying treatment opportunities easier than ever.