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Pituitary

Pituitary tumors are responsible for a majority of hormone abnormalities involving the pituitary glands.In autopsy studies of patients who did not have known pituitary disease, up to 20% had small tumors in their pituitary glands.

Cleveland Clinic's Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center staff, along with physicians specializing in endocrinology, diabetes and metabolism, neurosurgery, and radiation oncology work together with neuro-ophthalmologists and other specialists to treat patients diagnosed with a variety of pituitary disorders and conditions. This multidisciplinary team treats patients with disorders affecting the pituitary gland and parasellar region, including secretory and non-secretory pituitary brain tumors, craniopharyngiomas, and other parasellar tumors, hypopituitarism, and inflammatory diseases of the neuro-endocrine system.

State-of-the-art Diagnostic and Therapeutic Capabilities

Clinicians at Cleveland Clinic's Neuro-Endocrine Center provide state-of-the-art diagnostic and therapeutic modalities for advanced treatment of neuro-endocrine disorders such as a pituitary brain tumors, featuring such procedures as:

  • High field MRI
  • Functional imaging (fMRI)
  • Complete endocrinologic evaluation
  • Petrosal sinus sampling
  • Neuro-ophthalmologic evaluation

Surgery is the most common treatment for pituitary brain tumors. Depending on the patient's case, the surgeon may choose to perform a transsphenoidal hypophysectomy to remove the tumor through an incision in the nasal passage; a craniotomy to remove the tumor through an incision in the front of the skull; or stereotactic radiosurgery using focused, high-energy gamma rays without requiring an incision.

Treatment Options for Metastic Brain Tumors

Medical Therapy
  • Hormone replacement
  • Dopamine agonish (prolactinoma)
  • Somatostatin analog (acromegaly)
Microsurgery
  • Transsphenoidal tumor resection
  • Endoscopic tumor resection
  • Frameless stereotactic navigation
  • Intraoperative MRI
  • Microsurgical craniotomy
Radiosurgery
  • Gamma Knife Perfexion – the most up-to-date stereotactic radiosurgery technology for certain brain lesions allows outpatient therapy without the need for surgical incisions or protracted hospital recovery times.
  • Intensity Modulated Radiation Therapy
  • Conventional Radiation
  • Novalis Radiosurgery

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