Getting care for rare conditions like bone marrow failure and cytopenias can feel like a mountain you need to climb. But you don’t have to face it alone.
Your path might take turns you wouldn’t expect. But an exceptional team can help you move through those challenges and find the best steps forward. Our vast knowledge can help you get the best care possible. As one of the nation’s top research centers for bone marrow failure and cytopenias, you’ll get treatment from internationally renowned experts who understand the intricacies of these blood disorders.
At Cleveland Clinic, rare conditions like these aren’t uncommon to us. They’re our world. And when you come to us, you are, too. We work with you to get you the care you need and help you through your treatment plan.
We’ve published 450+ publications and have a proven track record of discoveries and innovations. Our team leads many industry-sponsored National Institutes of Health, Department of Defense and Leukemia & Lymphoma Society grants. Plus, we offer clinical trials and registries not widely available elsewhere.
We know that it takes a team to provide the best possible care. Bringing together knowledge and experience from many different academic and clinical fields, our providers work together to offer insightful and innovative treatment options. We also work with your other providers — particularly when you live far from our offices. We’ll communicate with your provider close to home to make sure your care continues smoothly. Meet our team.
When you come to see us, you’re our focus. Our team works together to craft a treatment plan that matches your needs. It doesn’t matter if you need a one-time consultation, comprehensive care or continuous care. We can help. And along the way, we’re here to answer your questions and help address your concerns. We offer unprecedented access to our providers through MyChart or direct communication with our offices — no chains of recorded messages and endless options just to get in touch. Our providers have the ability to contact other specialists in these diseases from around the world to make even more qualified recommendations.
We’re one of the top programs in the U.S. where doctors send their patients for these rare conditions — and we also see patients from across the world. Our staff sit on medical advisory groups that help create national recommendations and treatment standards. Our clinical expertise stems from our high volume of patients with these otherwise rare and very special conditions.
Getting care doesn’t always mean leaving home. Virtual visits allow you to get the same great care and attention from your provider online.
Cleveland Clinic is a trusted healthcare leader. We’re recognized in the U.S. and throughout the world for our expertise and care.
Bone marrow failure and cytopenias are a broad category of disorders in which blood cells aren’t produced the way they should. Maybe you’re thinking, “If I have one of these rare, specific conditions, will my provider know how to treat it?” With us, the answer is yes. Our team has experience working with these rare conditions.
As you get started with us, you learn about the wide range of services we offer, including:
The diseases and syndromes that fall under bone marrow failure and cytopenias are in two categories: things that you’re born with (inherited or congenital) and things you get over time (acquired).
Congenital/inherited
Acquired
Whether you’re newly diagnosed or your provider suspects you might have one of the rare conditions we treat, your first appointment will start with a conversation. We want to use this time to get to know you and learn about your experience. Get ready for a lot of questions. We’ll ask about your medical history, any symptoms you might have and other concerns. Feel free to share your story.
There are also some tests that we might do. Often, we do a physical exam at this early stage, or you might need diagnostic testing. Usually, you’ll have blood tests like a complete blood count (CBC) to measure how many red and white blood cells and platelets you have in your blood. Your provider may also want to do a bone marrow biopsy to take an even closer look at these counts.
Diagnosing a condition isn’t always straightforward. Sometimes, it takes time. But we have experience diagnosing unclear and complicated cases.
Throughout these tests, know that you can ask questions. Your team of providers is there for you, and they’ll help explain what’s going on.
You’re in charge of your care. And sometimes, this means getting a second opinion. You shouldn’t feel bad about asking for another provider’s opinion — it’s your health or the health of your loved one. Our highly skilled, experienced providers will spend time with you to help you better understand your diagnosis and which treatment options are best. We work with providers from all over the U.S., and we’re careful not to jeopardize your relationship with your current provider if you’re happy with them. As a team, we’ll help you get the best possible care.
Want a second opinion without the need to travel? Our virtual second opinions connect you with an expert without the need to leave home. You’ll get the guidance you need to help you move forward with confidence.
When you come to Cleveland Clinic, your care doesn’t happen in a vacuum. There’s a team of healthcare providers who will come together to care for you. You might work with:
We’ll also work seamlessly with your care team at home to make sure that they know what’s happening with your treatment.
You can get care at our Cleveland Clinic main campus or at Cleveland Clinic Weston Hospital in Florida.
Since bone marrow failure and cytopenias include a variety of diseases and syndromes, we’ll need to craft a treatment plan that’s specifically made for you. Your treatment might include any of the following options:
We may prescribe medications to stimulate your immune system. Depending on the type of immunosuppressant medication we recommend, you may take pills, get an injection or have it delivered intravenously (IV). We’ll keep a close eye on you while you’re on this medication and adjust it as needed.
Depending on your diagnosis, we might use medications that cause your bone marrow to produce more blood cells. If you have low blood counts or we anticipate a drop, this could be an option for you.
We often treat many bone marrow failure syndromes with red blood cell and platelet transfusions. But whether you need a blood transfusion will depend on your diagnosis. If we decide it’s a good therapy for you, you’ll get the transfusion through an IV over the course of a few hours.
Some bone marrow syndromes — such as myelodysplastic syndrome or, at times, large granular lymphocyte leukemia — may require chemotherapy. This treatment rids the bone marrow of abnormal cells and allows healthy stem cells to grow in their place. These healthy stem cells can then make normal blood cells again. Your provider may give you chemotherapy via pill, injection or IV.
For some bone marrow failure syndromes, like aplastic anemia, a bone marrow transplant is the best option. This treatment replaces your damaged bone marrow cells with healthy ones. Before the transplant, we’ll give you a strong dose of chemotherapy to kill diseased cells in the bone marrow. Then, you receive new cells through an IV, and they’ll move through your blood into your bone marrow.
Your care doesn’t stop after treatment. You’ll have regular follow-up appointments where we’ll check on how you’re doing and see if you need anything different. Sometimes, you have questions after treatment, or you have a symptom you’re unsure of. We’re here to help.
We’re very sensitive to the travel and time it takes to get to appointments. We’ll do everything we can to minimize your stress and inconvenience.
Hearing you might have a bone marrow failure and cytopenia disorder can make you wonder what to do next and who to go see. At Cleveland Clinic, we take a team approach. We work together — combining our highly specialized expertise and knowledge in this field — to provide the best care possible. Think of us as your guides. We’ll be by your side throughout your journey, guiding you through every step of the testing and treatment process. And when you have questions, we’ll be there to answer them. These conditions might be rare, but they’re not uncommon to us.
Getting an appointment with Cleveland Clinic’s bone marrow failure and cytopenias experts is easy. We’re here to help you get the care you need.
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