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Cardiac Consult

Cardiac Consult

A Cleveland Clinic podcast exploring heart, vascular and thoracic topics of interest to healthcare providers: medical and surgical treatments, diagnostic testing, medical conditions, and research, technology and practice issues.

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Featured Episode

Milind Desai, MD, and Per Wierup, MD
October 1, 2026

Management of Complex Aortic Valve Endocarditis

Milind Desai, MD, and Per Wierup, MD, discuss the evaluation and management of high-risk aortic valve endocarditis, including indications for urgent intervention and timing of surgery. They also review operative approaches to patients with heart failure, uncontrolled infection and embolic risk, highlighting the role of multidisciplinary expertise in complex endocarditis care Looking to refer a patient? Please reach out to our Physician Referral…

All Cardiac Consult Episodes

October 1, 2026

Management of Complex Aortic Valve Endocarditis

Milind Desai, MD, and Per Wierup, MD, discuss the evaluation and management of high-risk aortic valve endocarditis, including indications for urgent intervention and timing of surgery. They also review operative approaches to…

September 24, 2026

Lepodisiran and the Emerging Role of Oxidized Phospholipids in Lipoprotein(a) Risk

Luke Laffin, MD, speaks with Steven Nissen, MD, about findings from the ALPACA trial evaluating lepodisiran and its effects on oxidized phospholipids and lipoprotein(a). They discuss the potential mechanisms linking lipoprote…

September 17, 2026

Talking Tall Rounds®: Updates on Less Invasive Cardiac Surgery

In this excerpt from Tall Rounds®, Gianluca Torregrossa, MD, discusses minimally invasive and totally endoscopic coronary artery bypass grafting (TECAB), highlighting procedural advances that enable multi-vessel revasculariza…

September 10, 2026

CTX310 and the Future of Gene Editing for Lipid Disorders

Steven Nissen, MD, and Luke Laffin, MD, discuss one-year follow-up data for CTX310, a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3 to treat lipid disorders. They review the sustained reductions in LDL cholesterol and tr…

September 3, 2026

Evaluating Kylo-11 for Long-Acting Lipoprotein(a) Suppression

Steven Nissen, MD, and Ashish Sarraju, MD, discuss early clinical data on Kylo-11, a novel therapy that produced substantial reductions in lipoprotein(a) for up to one year after a single injection. Lowering lipoprotein(a), a…

August 26, 2026

Robotic Approaches to Mitral and Aortic Valve Surgery

Marc Gillinov, MD, and Per Wierup, MD, discuss the evolution of robotic valve surgery, including advanced mitral valve repair techniques, patient selection and expanding applications for aortic valve and coronary procedures.…

August 20, 2026

Infective Endocarditis Diagnosis and Management

Bo Xu, MD, and Shinya Unai, MD, discuss approaches to diagnosing and treating infective endocarditis, including indications for surgical intervention. The conversation highlights the role of multimodality imaging , individual…

August 13, 2026

Expanding Coronary Revascularization With TECAB

Donna Kimmaliardjuk, MD, and Gianluca Torregrossa, MD, discuss the expanding role of robotic coronary artery bypass grafting, including total endoscopic coronary artery bypass (TECAB). They explore how a tailored surgical app…

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