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Cleveland Clinic Cancer Advances Podcast

Cancer Advances

A Cleveland Clinic podcast for medical professionals exploring the latest innovative research and clinical advances in the field of oncology.

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Featured Episode

Natalie Jacobowski, MD
July 23, 2026

Integrating Goals-of-Care Discussions in Oncology Practice

How can oncologists initiate meaningful goals-of-care discussions earlier in the disease course? In this episode, Dr. Natalie Jacobowski outlines practical communication strategies, including language, timing and approaches to reduce stigma and align care with patient values. She emphasizes how early, transparent dialogue, and framing concerns as shared worries, can enhance decision-making across the cancer continuum, including for younger patien…

All Cancer Advances Episodes

July 23, 2026

Integrating Goals-of-Care Discussions in Oncology Practice

How can oncologists initiate meaningful goals-of-care discussions earlier in the disease course? In this episode, Dr. Natalie Jacobowski outlines practical communication strategies, including language, timing and approaches t…

July 9, 2026

Building Smarter Testicular Cancer Data Sets with Large Language Models

How can better data improve decision-making in a curable but nuanced disease like testicular cancer? This episode explores how large language models can turn unstructured clinical notes into actionable insights, helping clini…

June 18, 2026

Pre-Taxane Lutetium in Prostate Cancer: Changing the Treatment Algorithm

Is there a role for earlier integration of lutetium PSMA therapy in mCRPC management? Emerging evidence supports its use in the pre-taxane setting, prompting a shift in sequencing decisions. This episode outlines patient sele…

June 4, 2026

Rethinking "More Is Better": Deescalating Cancer Care

As cancer care becomes increasingly personalized, treatment deescalation is emerging as a key strategy to balance efficacy with quality of life. In this episode of Cancer Advances, Jame Abraham, MD, Enterprise Chair of Hemato…

May 21, 2026

Using Dynamic Models to Inform Treatment and Prognosis in AML

How can we better predict progression and outcomes in a disease where treatment decisions must be made in days, sometimes hours? In this episode of Cancer Advances, Moaath Mustafa Ali, MD, MPH, discusses emerging longitudinal…

May 14, 2026

Preserving Fertility During Pelvic Radiation: A Multidisciplinary Surgical Approach

Young patients requiring pelvic radiation face limited fertility preservation options. In this episode of Cancer Advances, Robert DeBernardo, MD, and Johanna Kelley, MD, both gynecologic oncologists at Cleveland Clinic, discu…

May 7, 2026

Optimizing Treatment Decisions in Muscle-Invasive Bladder Cancer

Shilpa Gupta, MD, Genitourinary Medical Oncologist, joins the Cancer Advances podcast to explore how perioperative immunotherapy and ctDNA are redefining management of muscle-invasive bladder cancer. She reviews emerging phas…

April 30, 2026

20 Years of Multidisciplinary Collaboration: Lessons from the Spine Tumor Board

Lilyana Angelov, MD, Neurosurgeon and Director of the Cleveland Clinic Gamma Knife Center, Samuel Chao, MD, Radiation Oncologist and Associate Director of the Gamma Knife Center; and Ajit Krishnaney, MD, Neurosurgeon in the C…

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