What is this medication?
PROPAFENONE (proe pa FEEN one) prevents and treats a fast or irregular heartbeat (arrhythmia). It is often used to treat a type of arrhythmia known as AFib (atrial fibrillation). It works by slowing down overactive electric signals in the heart, which stabilizes your heart rhythm. It belongs to a group of medications called antiarrhythmics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
COMMON BRAND NAME(S): Rythmol
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
- Heart disease
- High potassium level
- Kidney disease
- Liver disease
- Low blood pressure
- Lung or breathing disease like asthma, chronic bronchitis, or emphysema
- Slow heart rate
- An unusual or allergic reaction to propafenone, other medications, foods, dyes, or preservatives
- Pregnant or trying to get pregnant
How should I use this medication?
Take this medication by mouth with a glass of water. Follow the directions on the prescription label. You can take this medication with or without food. Take your doses at regular intervals. Do not take your medication more often than directed. Do not stop taking except on the advice of your care team.
Talk to your care team regarding the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medication?
Do not take this medication with any of the following:
- Arsenic trioxide
- Certain antibiotics like clarithromycin, erythromycin, grepafloxacin, pentamidine, sparfloxacin, troleandomycin
- Certain medications for depression or mental illness like amoxapine, haloperidol, maprotiline, pimozide, sertindole, thioridazine, tricyclic antidepressants
- Certain medications for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- Certain medications for irregular heartbeat like dronedarone
- Certain medications for malaria like chloroquine, halofantrine
This medication may also interact with the following:
- Certain medications for angina or blood pressure
- Certain medications for asthma or breathing difficulties like formoterol, salmeterol
- Certain medications that treat or prevent blood clots like warfarin
- Local anesthetics
- Other medications that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medication?
Your condition will be monitored closely when you first begin therapy. Often, this medication is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your care team for regular checks on your progress. Because your condition and use of this medication carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and care team.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
If you are going to have surgery, tell your care team that you are taking this medication.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Heart failure—shortness of breath, swelling of the ankles, feet, or hands, sudden weight gain, unusual weakness or fatigue
- Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
- Infection—fever, chills, cough, sore throat
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
- Change in taste
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
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