About C5Research | Cleveland Clinic

Cleveland Clinic physician Steven E. Nissen, MD, Chief Academic Officer, Heart, Vascular & Thoracic Institute

C5Research is a team of experienced and dedicated clinical trial specialists within the Heart, Vascular & Thoracic Institute of Cleveland Clinic. We bring scientific and clinical leadership in cardiovascular disease in combination with operational excellence to conduct Phase II-IV multicenter clinical trials.

Since 1991, we have leveraged the clinical expertise of over 500 physicians across multiple specialties throughout Cleveland Clinic providing academic leadership and coordination for trials ranging in size from <100 to 24,000 patients.

Our expertise in cardiovascular disease is recognized worldwide, as evidenced by U.S. News & World Report consistently naming Cleveland Clinic as one of the nation's top hospitals in its annual "America's Best Hospitals" survey, as well as Cleveland Clinic's heart program No. 1 in the nation since 1995.

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What We Do

We are an academic group dedicated to achieving the highest quality work following ICH/GCP guidelines.

We understand industry timelines and commit to delivering on time. We bring world class academic leadership to clinical trials and a viewpoint and independence that satisfies the demanding peer-reviewed scrutiny of the academic and scientific community.

Working closely with Cleveland Clinic physicians, we provide:

Overall trial leadership
Project and Site Management capabilities with extensive clinical and research experience and expertise allowing for successful implementation, conduct, and conclusion of clinical trials.
Independent oversight of clinical trial committees (Data Safety Monitoring, Executive and Steering Committees)
Imaging Core Laboratories that perform high quality and timely image analysis
Clinical Events Committee (CEC) that is highly reliable and timely in adjudicating clinical events
Statistics to support protocol development, independent review of study results and manuscript preparation
Publication of trial results in top tier medical journals having a major impact on the practice of medicine

Our Team

C5R Physician Leadership

	A. Michael Lincoff, MD Director, C5Research [email protected]
	Venu Menon, MD Associate Director of C5Research and Director of Clinical Events Committee [email protected]
	Steven E. Nissen, MD Chief Academic Officer, Heart, Vascular & Thoracic Institute [email protected]
	Wael A. Jaber, MD Director, Cardiovascular Imaging Core Laboratory j[email protected]
	Rishi Puri, MBBS, PhD, FRACP Director, Atherosclerosis Imaging Core Laboratory [email protected]
	Vidyasagar Kalahasti, MD Associate Director, Clinical Events Committee [email protected]
	Paul Bishop, PhD, RVT Director, Vascular Core Lab [email protected]