Cardiac Consult

Featured Episode

September 10, 2026

CTX310 and the Future of Gene Editing for Lipid Disorders

Steven Nissen, MD, and Luke Laffin, MD, discuss one-year follow-up data for CTX310, a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3 to treat lipid disorders. They review the sustained reductions in LDL cholesterol and triglycerides, and the potential role of one-time gene-editing therapies in cardiovascular prevention and lipid management. Read the article. https://consultqd.clevelandclinic.org/effects-of-crispr-cas9-gene-editing-for-dyslip…

All Cardiac Consult Episodes

September 10, 2026

CTX310 and the Future of Gene Editing for Lipid Disorders

September 3, 2026

Evaluating Kylo-11 for Long-Acting Lipoprotein(a) Suppression

Steven Nissen, MD, and Ashish Sarraju, MD, discuss early clinical data on Kylo-11, a novel therapy that produced substantial reductions in lipoprotein(a) for up to one year after a single injection. Lowering lipoprotein(a), a…

August 26, 2026

Robotic Approaches to Mitral and Aortic Valve Surgery

Marc Gillinov, MD, and Per Wierup, MD, discuss the evolution of robotic valve surgery, including advanced mitral valve repair techniques, patient selection and expanding applications for aortic valve and coronary procedures.…

August 20, 2026

Infective Endocarditis Diagnosis and Management

Bo Xu, MD, and Shinya Unai, MD, discuss approaches to diagnosing and treating infective endocarditis, including indications for surgical intervention. The conversation highlights the role of multimodality imaging , individual…

August 13, 2026

Expanding Coronary Revascularization With TECAB

Donna Kimmaliardjuk, MD, and Gianluca Torregrossa, MD, discuss the expanding role of robotic coronary artery bypass grafting, including total endoscopic coronary artery bypass (TECAB). They explore how a tailored surgical app…

August 6, 2026

Stenting, Surgery and Hybrid Strategies for Coronary Disease

Faisal Bakaeen, MD, and Grant Reed, MD, discuss recent advances in the treatment of coronary artery disease, including drug-coated balloons, intravascular imaging, calcium modification and evolving PCI strategies. They also e…

July 30, 2026

Individualizing Aspirin Therapy in Preventive Cardiology

Luke J. Laffin, MD, and Vikas Sunder, MD, discuss the evolving role of aspirin in primary prevention, emphasizing individualized assessment of each patient's cardiovascular and bleeding risk. They explore how coronary artery…

July 23, 2026

Robotic Lung Transplantation

Kenneth McCurry, MD, and Gregory Jones, MD explores protocol development and future applications of robotic technology in lung transplantation.

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