The Center for Personalized Genetic Healthcare (CPGH) offers comprehensive preconception and prenatal genetic services to individuals who are at high risk of having a baby with a birth defect or genetic disorder. Although most babies are born healthy, between 3 to 5 percent of babies are born with some type of birth defect or learning problem.

Preconception and prenatal genetic counseling is a service that can be incorporated into your reproductive care. CPGH offers genetic counseling and, if appropriate, genetic testing.

Scheduling an Appointment

Prior to requesting an appointment, you will need to obtain a referral from your physician. If you are a patient outside the Cleveland Clinic health system, please have your physician complete a referral form and fax to 216.445.6935. To learn more about how to prepare for your appointment, review the "Before Your Visit" tab.

Our Team

Our Team

The Center for Personalized Genetic Healthcare (CPGH) is committed to providing comprehensive clinical genetic services, education and support to patients and family members. Our team of genetic experts will work with other Cleveland Clinic primary care providers and specialists to personalize your care by incorporating your genetic information into your overall health care plan.

Clinical Geneticists

Genetic Counselors

  • Marissa Coleridge, MS, CGC
  • Olga Latosh, MS, CGC
Who Should Be Seen

Who Should Be Seen

You should consider having a genetic evaluation if you have a family and/or personal history of the following:

  • Advanced maternal age (age 35 or older)
  • First trimester/nuchal screening pre-test education/counseling
  • Abnormal maternal serum screening
  • Concerns about genetic disease because of ethnicity
  • Abnormal ultrasound findings
  • Recurrent miscarriages
  • Family/personal history of genetic condition
  • Family/personal history of birth defect(s)
  • Family/personal history of learning and/or developmental disabilities
  • Environmental or medication exposures during pregnancy
  • Considering Preimplantation Genetic Diagnosis (PGD)

Contact your primary care provider or the Center for Personalized Genetic Healthcare (CPGH) to discuss whether a genetic counseling evaluation is appropriate for you.

What to Expect

What to Expect

Before Your Visit

Physician Referral
Prior to requesting an appointment, you will need to obtain a physician referral. If you are a patient outside the Cleveland Clinic health system, please have your physician complete a referral form and fax to 216.445.6935.

Collect Your Medical Records
If you are a patient outside the Cleveland Clinic health system, you should send an authorization for the release of medical records form to each external facility. You may arrange to have medical records faxed (30 pages or less) to our department at 216.445.6935 or sent postal mail.

Cleveland Clinic
Center for Personalized Genetic Healthcare
Attn: Preconception and Prenatal Genetics
9500 Euclid Ave. R4
Cleveland, OH 44195

Collect Your Family Health History
To make the most out of your visit, you should gather family health history information prior to your appointment. It may be helpful for you to talk with your relatives about genetic or developmental conditions running in your family. Specifically, you will want to discuss the following:

  • Who in the family has had physical problems since birth, birth defects, developmental disabilities, learning problems, infertility, inherited conditions or genetic disorders?
  • Did any family members die at a young age from common medical problems?
  • Who in the family had difficulties with conceiving or miscarriages?
  • Had anyone in the family had genetic testing?

At Your Visit

We will provide personalized expert genetic counseling and education to you and your family. During your visit, you will see a genetics expert (genetic counselor and/or clinical geneticist) for a genetics evaluation. You may also be scheduled with other Cleveland Clinic providers during your visit depending on your medical needs and physician availability.

Our comprehensive method for genetic counseling involves:

  • Diagnosis of a genetic condition through review of family and medical history, examination by a clinical geneticist, and if appropriate, genetic testing.
  • Review of any abnormal test results (e.g., ultrasound or blood testing), if applicable
  • Education about your specific diagnosis and any associated health risks if known
  • Health planning for the future that details suggestions for appropriate medical management
  • Discussion of health risks to family members
  • Recommendations regarding genetic testing for at-risk family members and coordination of testing, if desired

Following Your Visit

After your visit, it may take anywhere from a few days up to two weeks for your clinical appointment notes to reach the healthcare providers that you requested to receive a copy. We are also glad to communicate with your healthcare providers about your case as needed. You are always welcome to follow up with us with questions regarding your visit.

Cost & Insurance

Cost & Insurance

Genetic counseling and testing are billed as two separate services.

Genetic Counseling

There currently is no charge for genetic counseling visits. Please note this policy is subject to change. To confirm the cost of genetic counseling visits, contact us at 216.636.1768.

Genetic Testing

If genetic testing is indicated, your genetic counselor will discuss costs and insurance coverage during your appointment.

Some patients are concerned that their genetic information may be used against them. To learn about your patient rights and protections in place to prevent genetic discrimination, read this article on GINA.

Genetic discrimination fact sheet (GINA)

To learn more about billing options and financial assistance, review our billing and insurance information.



The Center for Personalized Genetic Healthcare (CPGH) is expanding rapidly. Patients can now make appointments to be evaluated at main campus clinics and select regional hospitals.

To schedule an appointment, please call 216.636.1768 or 800. 998.4785.

Main Campus

Regional Locations