Cleveland Clinic Cancer Center (Taussig) Outcomes
Head and Neck Cancer
Adjuvant Radiation Following Clear Margin Resection of High T-Stage Cutaneous Squamous Cell Carcinoma Halves the Risk of Local and Locoregional Recurrence: A Dual-Center Retrospective Study
Although adjuvant radiation (ART) following clear margin surgery is recommended for select high-risk cutaneous squamous cell carcinomas, efficacy data are limited. The objective of this study was to evaluate the impact of ART on outcomes following clear margin surgery for high T-stage cutaneous squamous cell carcinomas.
Adjusted Cumulative Incidence Curves for Local Recurrence
BWH T2b and T3 Tumors
![](https://www.clevelandclinic.org/lp/outcomes/TCI-2021-HN-R-2-1.jpg)
ART, adjuvant radiation; LR, local recurrence.
Adjusted Cumulative Incidence Curves for Locoregional Recurrence
BWTH T2b and T3 Tumors
![](https://www.clevelandclinic.org/lp/outcomes/TCI-2021-HN-R-2-2.jpg)
ART, adjuvant radiation.
Adjusted Cumulative Incidence Curves for Local Recurrence
High Risk
![](https://www.clevelandclinic.org/lp/outcomes/TCI-2021-HN-R-2-3.jpg)
ART, adjuvant radiation; LR, local recurrence.
Adjusted Cumulative Incidence Curves for Locoregional Recurrence
High Risk
![](https://www.clevelandclinic.org/lp/outcomes/TCI-2021-HN-R-2-4.jpg)
ART, adjuvant radiation.
Adjusted Cumulative Incidence Curves for Locoregional Recurrence
Low Risk
![](https://www.clevelandclinic.org/lp/outcomes/TCI-2021-HN-R-2-5.jpg)
ART, adjuvant radiation.
ART following clear margin surgery for high T-stage cutaneous squamous cell carcinomas resulted in half the risk of LR and LRR.