The Chronic Pain Rehabilitation Program (CPRP) is a comprehensive, interdisciplinary functional rehabilitation program designed to treat patients with chronic non-malignant chronic pain. Starting in 1999, the CPRP has maintained an IRB-approved data registry that includes clinical, demographic, and functional data from all patients evaluated and treated in the program. The current registry contains information from over 3100 program completers, and data are currently being collected at program admission, discharge, 6- and 12-months post-treatment. These data have been used to evaluate overall clinical treatment outcomes, as well as questions regarding the efficacy of interdisciplinary treatment in a chronic pain program for patients with specific chronic pain diagnoses (e.g. fibromyalgia, chronic pelvic pain, headache, or back pain).

A major focus of our research has been to examine how patient outcomes are affected by variables such as medication usage, demographic factors, personality variables, mood, and employment status. Outcomes are typically assessed in terms of reduction in pain severity, pain related functional impairment, normalization of mood and minimization of medication use. Projects currently being completed include further analysis of functional behavioral (e.g., physical therapy) outcomes, longitudinal maintenance of treatment gains following program discharge, and associations between subjective clinical outcomes and psychophysiological measures of pain sensitivity and central sensitization.

Darcy Mandell, PhD



Prospective Comparison of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and MMPI-2-Restructured Form (MMPI-2-RF) in Predicting Treatment Outcomes Among Patients with Chronic Low Back Pain. Journal of clinical psychology in medical settings (2018): 1-14., Anthony M., Judith Scheman, and Yossef S. Ben-Porath.

Evaluating objective and subjective treatment benefits in women with chronic pelvic pain treated in an interdisciplinary chronic pain rehabilitation. The Journal of Pain19(3), S31. (published abstract), A., Huffman, K., & Jimenez, X. (2018).

Sustained improvements in pain, mood, function and opioid use post interdisciplinary pain rehabilitation in patients weaned from high and low dose chronic opioid therapy. Huffman, K. L., Rush, T. E., Fan, Y., Sweis, G. W., Vij, B., Covington, E. C., Scheman, J., Mathews, M. (2017). Pain, 158(7), 1380-1394.

Additional evidence supporting the central sensitization inventory (CSI) as an outcome measure among chronic pain patients in functional restoration program care. The Spine Journal, 17(11), 1765.Jimenez, X. F., Aboussssouan, A., Mandell, D., & Huffman, K. L. (2017).

Severe Noncardiac Chest Pain Responds to Interdisciplinary Chronic Pain Rehabilitation. Psychosomatics.Jimenez, X. F. (2017).

Interdisciplinary treatment of patients with multiple sclerosis and chronic pain. In Nutrition and Lifestyle in Neurological Autoimmune Diseases (pp. 213-219).Sullivan, A. B., & Domingo, S. (2017).

Utilizing psychophysical measurements of central sensitization to evaluate the interdisciplinary treatment of fibromyalgia. The Journal of Pain, 18(4), S53. (published abstract)Huffman, K., Gopalakrishnan, R., Martincin, R., Aboussouan, A., Perry, E., Thompson, N., Sweis, G. & Jimenez, X. (2017).

Older adults with chronic non-cancer pain benefit from treatment in an interdisciplinary chronic pain rehabilitation program. Pain Medicine, 18(4), S53. (published abstract) K.M., Aboussouan A., Thompson N., Vij B., Huffman K.  (2017).

A multilevel path model analysis of the relations between sleep, pain, and pain catastrophizing in chronic pain rehabilitation patients. Scandinavian journal of pain, 10, 122-129.Wilt, J. A., Davin, S., & Scheman, J. (2016). 

Chronic pelvic pain is effectively treated in an interdisciplinary chronic pain rehabilitation program. The Journal of Pain, 17(4), S108. (published abstract). Aboussouan, A., Martincin, K., & Huffman, K. (2016).  

Nonopioid substance use disorders and opioid dose predict therapeutic opioid addiction. The Journal of Pain16(2), 126-134.Huffman, K. L., Shella, E. R., Sweis, G., Griffith, S. D., Scheman, J., & Covington, E. C. (2015).

Variability in the relationship between sleep and pain in patients undergoing interdisciplinary rehabilitation for chronic pain. Pain Medicine, 15(6), 1043-1051., S., Wilt, J., Covington, E., & Scheman, J. (2014).

Retrospective outcome analyses for headaches in a pain rehabilitation interdisciplinary program. Headache: The Journal of Head and Face Pain54(3), 520-527., Y., Tepper, S. J., Covington, E. C., Mathews, M., & Scheman, J. (2014).

Interdisciplinary Pain Rehabilitation for Fibromyalgia: Evidence of Long-term Benefits. Pain Medicine, 15(3), 530-531. (published abstract), B., Huffman, K. L., Davin, S. A., & Scheman, J. (2014).

Opioid use 12 months following interdisciplinary pain rehabilitation with weaning. Pain Medicine14(12), 1908-1917.Huffman, K. L., Sweis, G. W., Gase, A., Scheman, J., & Covington, E. C. (2013).

The role of exercise and types of exercise in the rehabilitation of chronic pain: specific or nonspecific benefits. Current pain and headache reports16(2), 153-161.Sullivan, A. B., Scheman, J., Venesy, D., & Davin, S. (2012). 

Members & Collaborations

Members & Collaborations

  • Xavier Jimenez, MD (PI)
  • Darcy Mandell, PhD (PI)
  • Alix Aboussouan, BS (study coordinator)
  • Sara Rispinto, PhD
  • Sara Davin, PsyD
  • Steven Krause, PhD
  • Taylor Rush, PhD
  • Brittany Lapin, PhD
  • Nicolas Thompson, MS
  • Kelly Huffman, PhD (collaborator)
  • Yossef Ben-Porath, PhD (collaborator)
  • Youran Fan, PhD (collaborator)