Our research compares the safety and effectiveness of electroconvulsive therapy (ECT), an existing strategy for treatment resistant depression that alleviates depressive symptoms by using an electric current, to the anesthetic drug ketamine, which has been shown to be efficacious for treatment-resistant depression but has not yet been compared to ECT. The project will focus specifically on the outcomes most important to patients: quality of life and relief from depression without the risk of significant side effects such as memory loss.
2016 PCORI TRD-1511-33648 Electroconvulsive Therapy versus Ketamine for Treatment Resistant Depression
Members & Collaborations
- Roman Dale, MD
External Relationships and Collaborations
- Sanjay Mathew MD, Baylor University
- Gerard Sanacora MD, PhD, Yale University
- James Murrough MD, Mt. Sinai School of Medicine