Nontuberculous mycobacterial (NTM) lung disease is an infection that’s challenging to diagnose and treat. It’s due to bacteria in the soil, dust and air. You're more likely to experience this condition if you are living with chronic lung disease.
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This rare condition occurs when nontuberculous mycobacteria (NTM) causes a lung infection.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
There are two types of NTM lung disease:
Nontuberculous mycobacteria are a family of slow-growing bacteria that exist in soil, water and dust, making them impossible to avoid. They can be resistant to disinfectants. They can also survive high temperatures that typically destroy other types of bacteria.
The severity of infection, treatment approach and prognosis depend on which bacteria strain is causing the infection and whether the disease is nodular bronchiectatic or cavitary. They include:
You're more likely to experience an NTM lung infection if you're living with certain types of predisposing conditions like other types of lung disease. These include:
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You may also be at risk if you’re over age 65, have conditions that weaken your immune system or take medications that suppress your immune system. These include:
The most common sign is a cough. It may:
Other NTM infection symptoms include:
NTM bacteria don’t pass from person to person, so it isn’t contagious. However, infections in people with cystic fibrosis have spread to other people with cystic fibrosis although this is rare. Researchers are still determining whether NTM lung infections are among these.
NTM lung disease is challenging to diagnose because its symptoms aren't specific and are like many other, more common conditions. Diagnosis is made by the presence of symptoms, changes in your chest X-ray or CT scan and the growth of NTM in a sputum (the saliva and mucus you cough up) sample. If you have an infection, it’s essential to determine which strain of bacteria is causing it.
Evaluations may include:
Many people have NTM lung disease for years before receiving a diagnosis. The longer you have it, the higher your risk of complications. If you're undergoing lung disease treatment and your symptoms continue to worsen, you might benefit from NTM infection testing.
The best care comes from healthcare providers who have experience treating this disease. These include pulmonologists and infectious disease doctors.
The treatment that’s right for you depends on the bacteria strain, type of NTM lung disease and your health history. Care typically includes taking antibiotics for several months.
For more severe forms of the disease, surgery is sometimes necessary to remove infected lung tissue. Your providers are more likely to consider surgery if your disease doesn’t respond to antibiotics or if you can’t tolerate treatment. People with Mycobacterium avium complex sometimes need surgery to stop the bleeding that the infection sometimes causes.
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Being on long-term antibiotics can cause side effects like vomiting, diarrhea and loss of appetite. Some antibiotics can cause hearing or vision changes and your healthcare provider will monitor these during treatment. These issues can make it difficult to go about your day. If you're struggling to keep up treatment, tell your healthcare provider. You shouldn't stop taking antibiotics without first talking to your provider.
It’s nearly impossible to avoid NTM exposure. But there are steps you can take to lower the risk of an NTM lung infection.
These include:
The outlook varies, but many people make a full recovery, especially if you have non-cavitary disease. Your chances of getting better depend on:
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Even with successful treatment, some people experience NTM lung disease more than once.
Airway infections from NTM bacteria can make everyday life challenging. But there are steps you can take to feel your best. These include:
A note from Cleveland Clinic
NTM lung disease is an infection caused by slow-growing bacteria found in soil and water. People living with other lung conditions are more likely to experience this condition. It can be challenging to detect and treat, but many people make a full recovery. If you have or are at risk for this disease, it’s helpful to avoid moisture and wear a mask when outdoors.
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Last reviewed on 03/27/2022.
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