Radiation enteritis happens when radiation damages sensitive tissue in your intestines. It may occur during treatment or months after you’re finished. Some people experience mild symptoms, while others have long-lasting discomfort and complications.
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Radiation enteritis is a condition that occurs when radiation therapy causes damage to your intestines. Radiation therapy uses radioactive substances to destroy abnormal cells. It’s a common treatment for cancer and certain blood disorders.
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Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy
Other terms that describe this condition include:
The condition can be acute or chronic:
Radiation enteritis is far less common than it used to be. When older techniques of radiation therapy were delivered to your abdomen or pelvis, up to half of the people undergoing treatment could develop radiation enteritis. With modern techniques of radiation therapy, your risk of chronic radiation enteritis is much lower.
Some people face a higher risk due to:
Treatment typically requires regular exposure to radioactive substances for several weeks. When radiation reaches healthy cells, it causes inflammation and tissue damage. Cells in the lining of your intestines are more sensitive to the effects of radiation.
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Repeated exposures can destroy cells responsible for blocking infections and regulating fluid levels. The more doses you receive and the larger the area of bowel treated, the more likely you’re to develop radiation enteritis.
Symptoms may include:
Ongoing irritation and inflammation in your intestines can lead to:
Healthcare providers often make a diagnosis by asking you about your symptoms and your history of radiation exposure.
Additional testing may be necessary to rule out other conditions or assess severity. These include:
It might not be possible to repair chronic intestinal cell damage from radiation exposure. But medical management of radiation enteritis can help you stay comfortable and avoid complications.
Your care may include:
The options that are right for you depend on the type of complication. Strictures, fistulas and perforations often need surgery. You may need supplements or tube feeding if you aren’t getting enough nutrients.
There are steps your care team can take to protect your intestines during radiation therapy. These include:
People with acute radiation enteritis typically feel better within a few weeks. If you have chronic radiation enteritis, it can take several months.
The benefits of radiation for cancer treatment typically outweigh the risks of developing radiation enteritis. That’s why it’s usually essential to continue radiation therapy, even if it makes you sick.
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If you have concerns about how radiation enteritis may affect your health, talk with your healthcare provider. They can discuss potential options, like changing the frequency or dose of radiation therapy or other treatments for radiation enteritis symptoms.
Paying careful attention to your diet and fluid intake can ease discomfort and promote healing.
Avoid consuming foods and beverages that are difficult to digest. These include:
Eat high-nutrient foods that are easy on your stomach, such as:
A note from Cleveland Clinic
If you’re undergoing radiation therapy, there are steps healthcare providers can take to shield healthy tissue from radiation exposure. If you’re experiencing symptoms of radiation enteritis, talk to your healthcare provider. Treatments can relieve discomfort and lower the risk of complications.
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Last reviewed on 04/25/2022.
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