What is Dyssynergia Cerebellaris Myoclonica?

Dyssynergia Cerebellaris Myoclonica refers to a collection of rare, degenerative, neurological disorders characterized by epilepsy, cognitive impairment, myoclonus, and progressive ataxia. Symptoms include seizures, tremor, and reduced muscle coordination. Onset of the disorder generally occurs in early adulthood. Tremor may begin in one extremity and later spread to involve the entire voluntary muscular system. Arms are usually more affected than legs. Some of the cases are due to mitochondrial abnormalities.

Is there any treatment?

Treatment of Dyssynergia Cerebellaris Myoclonica is symptomatic. Myoclonus and seizures may be treated with drugs like valproate.

What is the prognosis?

The progression of the disorder is usually 10 years or longer.

What research is being done?

The NINDS supports a broad range of research on neurodegenerative disorders such as Dyssynergia Cerebellaris Myoclonica. The goals of this research are to find ways to prevent, treat, and cure these kinds of disorders.


National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institutes of Health, DHHS
31 Center Drive, MSC 2320
Bethesda, MD 20892-2320
Tel: 301.496.7243/800.241.1044 800.241.1055 (TTD/TTY)

National Ataxia Foundation (NAF)
2600 Fernbrook Lane North, Suite 119
Minneapolis, MN 55447-4752
Tel: 763.553.0020
Fax: 763.553.0167

National Organization for Rare Disorders (NORD)
P.O. Box 1968
(55 Kenosia Avenue)
Danbury, CT 06813-1968
Tel: 203.744.0100 Voice Mail 800.999.NORD (6673)
Fax: 203.798.2291

Source: National Institutes of Health; National Institute of Neurological Disorders and Stroke

This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. This document was last reviewed on: 2/14/2011…#6095