Lung Volume Reduction Program

Lung Volume Reduction Program

Emphysema patients suffer from debilitating shortness of breath due to hyperinflation. The aim of lung volume reduction (LVR) is to reduce hyperinflation in patients with chronic obstructive pulmonary disease (COPD), thereby improving dyspnea and quality of life. The National Emphysema Treatment Trial (NETT), which Cleveland Clinic participated in, has shown that, in appropriately selected patients, the procedure is associated with an improvement in symptoms and survival.

Cleveland Clinic’s LVR surgery program predates the NETT and consists of teams from the Respiratory Institute and Department of Thoracic Surgery from the Heart, Vascular and Thoracic Institute. Cleveland Clinic’s program offers video-assisted thoracoscopic surgery, a less morbid procedure compared with median sternotomy in achieving LVR.

Potential candidates are screened and evaluated in the Center for Comprehensive Care in COPD at the Respiratory Institute. Thoracic surgeons, pulmonologists, radiologists, advanced practitioners, and respiratory therapists meet regularly to discuss the complex cases of patients referred for LVR surgery, and consensus recommendations are then shared with referring physicians. Because of the extensive preoperative and longitudinal management these patients require, Cleveland Clinic has built a program that facilitates preoperative workup. Whenever possible, Cleveland Clinic works with local pulmonary rehabilitation programs to prepare patients for the procedure. When patients are brought to Cleveland, testing and clinical assessment are carried out through coordinated appointments that allow rapid patient evaluation.

The COPD center began performing bronchoscopic valve therapy starting in July 2019 and since that time 16 bronchoscopic valve therapy procedures have been performed in 13 patients (3 procedures for repositioning of the valves). Elective surgeries and respective evaluations were halted for several months due to COVID-19; the program restarted in September 2020. In 2021, Cleveland Clinic screened 180 patients and performed 9 LVR surgeries.