Pericardial Disease

Pericardial Disease

Pericardial Disease: Patient Volume

2020 – 2023

Pericardial disease includes a group of conditions that affect the pericardium — the double-layered sac that surrounds the heart. Cleveland Clinic's Center for the Diagnosis and Treatment of Pericardial Disease serves patients with a variety of pericardial syndromes.

Cleveland Clinic physicians manage the care of a large volume of patients with pericardial disease. In 2023, a total of 3048 patients, including 573 new patients, were seen in the center. The multispecialty approach used at Cleveland Clinic involves cardiologists, cardiac surgeons, imaging specialists, and rheumatologists. This method of care provides each patient with a plan of care that involves enhanced collaboration.

Source: EPIC

Pericardial Outpatient Clinic: Volume of New Consult Patients, by Diagnosis

2023, N = 573

Cleveland Clinic treats patients with all types of pericardial disease. In 2023, a total of 316 (55.14%) new patients seen in the pericardial outpatient clinic had acute, recurrent, chronic, or constrictive pericarditis.

Source: EPIC

Pericardial Outpatient Clinic: Volume of New Consult Patients, Causes of Pericarditis

2023, N = 573

There are various causes of pericarditis. The condition is often idiopathic or related to a virus. In 2023, a total of 302 (52.7%) new patients at Cleveland Clinic had idiopathic or viral pericarditis.

Source: Pericardial registry

ᵃ Pericardial Injury includes: postcardiac surgery, catheter ablation, coronary artery stent, cardiac electronic device placement, or trauma
ᵇ Other includes: bacterial, effusion, malignancy, or unclear cause of pericarditis

Pericardial Procedures: Volume and Type

2023, N = 305

The majority of pericardial procedures performed at Cleveland Clinic in 2023 were pericardial window procedures. This treatment is used to drain large pericardial effusions using an echo-guided approach. The echocardiography used during the procedure improves outcomes.

Source: Pericardial registry

Fig. 1 The pericardium is divided above the right ventricle. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography ©2022. All Rights Reserved.)

Fig. 2 The aorta and right side of the heart is dissected. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography © 2022. All Rights Reserved.)

right and left phrenic nerve

Fig. 3 After initiating cardiopulmonary bypass, the right and left phrenic nerve is dissected as a fat pedicle. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography ©2022. All Rights Reserved.)

diaphragmatic portion and the posterior pericardium

Fig. 4 The diaphragmatic portion and the posterior pericardium are removed. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography © 2022. All Rights Reserved.)

completed pericardiectomy.

Fig. 5 Completed pericardiectomy. (Reprinted with permission, Cleveland Clinic Center for Medical Art & Photography © 2022. All Rights Reserved.)

New Paradigm Shift in Management of Recurrent Pericarditis

Summary of the landmark trials of medications used for pericarditis. The decision to treat, escalate, taper, or stop therapy depends on the extent of inflammation. Clinical experience, advanced cardiac imaging, and use of the latest evidence results in this updated algorithm for the management of pericarditis.

Reference: Kumar S, Khubber S, Reyaldeen R, et al. Advances in Imaging and Targeted Therapies for Recurrent Pericarditis: A Review. JAMA Cardiol. 2022;7(9):975–985. doi:10.1001/jamacardio.2022.2584