Emergency icon Important Updates
Title Chairman, Department of Physical Medicine & Rehabilitation
Department Physical Medicine and Rehabilitation
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English, French
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Mellen Center

Cleveland Clinic Main Campus

9500 Euclid Avenue
Cleveland, OH 44195

Specialties & Treatments

Treatment & Services

  • Botulinum Toxin Injections
  • Gait Assessment
  • Intrathecal Baclofen Pump
  • Long-Term Care
  • Neuro Rehabilitation
  • Physical Medicine and Rehabilitation
  • Spasticity Management
View all 7 Treatment & Services +

Specialty in Diseases & Conditions

  • Adult Cerebral Palsy
  • Amyotrophic Lateral Sclerosis (ALS)
  • Multiple Sclerosis
  • Spasticity
  • Spinal Cord Injury
  • Stroke
  • Traumatic Brain Injury
View all 7 Specialties +


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Francois Bethoux, MD

Francois Bethoux, MD, serves as the Director of Rehabilitation Services at the Cleveland Clinic Mellen Center. He was born in 1964 in Paris, France. He completed his medical studies and residency in Physical Medicine and Rehabilitation in Lyon, France. After moving to the United States to complete a Neuroimmunology fellowship at the Mellen Center for Multiple Sclerosis Treatment and Research (affiliated with the Cleveland Clinic Foundation), he remained on staff and today serves as the Director of Rehabilitation Services. 

Dr. Bethoux's research interests include outcomes measurements in both general and multiple sclerosis (MS)-specific neurorehabilitation, gait analysis and evaluation of symptomatic therapies and rehabilitative interventions for spasticity in MS and other disorders of the central nervous system.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Cleveland, OH

Fellowship - MetroHealth Medical Center
Research Fellow-Funct. Elect.
Cleveland, OH United States

Graduate School - University of Burgundy
Diploma of Special Studies in
Dijon, France,

Residency - University Hospitals of Saint Etienne
PM & R

Internship - University Hospitals of Lyon
Internal Medicine
69002 Lyon,,

Medical Education - Alexis Carrel Medical School
Lyon, France, France


  • Physical Medicine & Rehabilitation

Specialty Interests

neuro-rehabilitation, spasticity management

Awards & Honors

  • Principal Investigator, “Efficacy Of  A Hip  Flexion Assist Orthosis In Ambulatory Multiple Sclerosis Patients,” National Multiple Sclerosis Society grant, 2010-2012
  • Principal Investigator, “Randomized, controlled trial of rehabilitation following acute relapses of MS,” study funded by the National Multiple Sclerosis Society, 2000-2003

Innovations & Patents

  • Participated in the design and testing of a new leg brace (hip flexion assist orthosis) in patients with multiple sclerosis. A pilot study of the brace was funded by the National Multiple Sclerosis Society. The results of the study were accepted for publication in the Archives of Physical Medicine and Rehabilitation. Patients with hip flexor weakness using the brace have experienced significant improvement of walking performance and leg strength.
Research & Publications

Research & Publications

See publications for Francois Bethoux, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 9/13/2023, Dr. Bethoux has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Bethoux receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Royal Clinics

Royalty Payments. Dr. Bethoux receives or has the right to receive royalty payments for inventions or discoveries commercialized through the companies shown below:

  • Springer
  • Biogen Idec, Inc.
  • Qr8 Health, Inc.

Right to Future Distribution of Cleveland Clinic Financial Interest. Dr. Bethoux may receive future financial benefits from the Cleveland Clinic for inventions or discoveries commercialized through the companies shown below:

  • Qr8 Health, Inc.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

107 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Courtesy, Respect & Concern 4.9
Patient Rating of Doctor 4.9

25 Patient Comments

Reviewed on Jun 14, 2024

Dr Bethoux is an outstanding physician and person. He always treats Andy with the utmost kindness & keeps his parents well informed. Dr Bethoux is very personable, skilled and completes Andy's procedures quickly and as pain free as possible. We always look forward to seeing Dr. Bethoux & receiving such exceptional care.

Reviewed on Jun 14, 2024

As described earlier, we have always received the very best care with Dr. Bethoux, his staff and the Cleveland Clinic.

Reviewed on Jun 6, 2024

Everything is good my doctor is the best of the best

Reviewed on Jun 6, 2024

As I said mt doctor is the best of the best

Reviewed on Jun 5, 2024

Dr Bethoux is always professional! His knowledge and concern for his patient is evident. It's apparent his team has the upmost respect for him, as I do! He asks questions and demonstrates an awareness of my entire treatment plan regardless of whether the practitioner(s) are CC employees or independent. He demonstrates genuine care for my well being! He's patient and thorough.

Reviewed on Apr 17, 2024

We can not say enough about the excellent professionalism and care shown to us by staff and by Dr Bethoux. Incredible physician.

Reviewed on Apr 17, 2024

I would like to be able to put 10 to all these, he was very exceptionally good. It's impossible to find health care providers that have these qualities anymore.

Reviewed on Apr 12, 2024

Dr.Bethoux is always excellent. Listens. Cares. Suggests possible treatment options.

Reviewed on Apr 12, 2024

I know that the doctor had a very busy clinic that day, but he took the time to carefully listen to me and answer all of my questions. I feel confident when talking to him that he respects my wishes and is listening to my point of view.

Reviewed on Feb 15, 2024

Dr. Bothoux has been my favorite CC physician. His concern and genuineness is Evident. His interaction is sincere. He explains and answers questions. The Mellen Center's fortunate to have a physician of his caliber.Dr Jameson Holloman, Fellow, is an outstanding student. He demonstrated professionalism and sincerity re: his ability to provide care to patients with MS. His future employer is fortunate to have him as an MS ambassador!

Reviewed on Feb 15, 2024

Outstanding teamwork! The CC's blessed to have the team of Dr Bethoux; Jennifer, PA; Jennifer, RN and Jackie, RN.

Reviewed on Feb 2, 2024

The doctor was very professional, has many years of experience. He was very helpful

Reviewed on Jan 17, 2024


Reviewed on Nov 29, 2023

I don't see how Dr. Bethoux could have been any better than he was.

Reviewed on Nov 28, 2023

Dr. Bethoux is a very good listener, an essential skill for treating patients. He allowed sufficient time for me to convey my concerns.

Reviewed on Nov 9, 2023

The doctor was fantastic! He is one of the best ones that I have ever had.

Reviewed on Oct 19, 2023

Dr. Beteaux was absolutely wonderful with our son and us. He took time to learn our son's medical history and the concerns we have. He was empathetic, caring and professional.

Reviewed on Oct 5, 2023

Dr. Bethoux is absolutely wonderful. He is highly skilled at what he does and is pleasant, compassionate & always focused on getting ultimate results. He works closely with Michelle's physical therapist who has a 22 yr. history with Michelle to ensure that optimal amounts of Botox are injected into the appropriate muscles.

Reviewed on Sep 27, 2023

Dr. Bethoux's knowledge and experience has been invaluable. He's helped us troubleshoot and develop a good action plan as we navigate new issues.

Reviewed on Sep 14, 2023

Dr Bethoux is a terrific prhysician. He listens & explains very well. Dr Bethoux is very skilled & fast in performing our son, Andy's Botox injections. Dr Bethoux speaks directly to Andy(who is disabled /CP) & shows empathy. A wonderful person & physician.

Reviewed on Sep 13, 2023


Reviewed on Aug 4, 2023

I was very impressed by The thorough evaluation and detailed explanations Provided. The physician was able to explain my situation In language that was easy to comprehend And I really got the impression that he understood what I was talking about.

Reviewed on Jul 19, 2023

Dr Bethoux was amazing during the appointment very thorough and compassionate. Offered additional support during the procedure

Reviewed on Jul 6, 2023

Dr. Bethoux was just the greatest and gave me some very good recommendations.

Reviewed on Jul 6, 2023

I would recommend Dr. Bethoux to everybody

Back to Top