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Department Pediatric Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Children & Adolescents Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Appendectomy
  • Childrens Primary Care
  • Department of Pediatric Surgery
  • Evaluation/Treatment of Antenatally Diagnosed Congenital Anomalies
  • Evaluation/Treatment of Pulmonary Sequestration / CCAM
  • Fundoplication Procedure for Children
  • Laparoscopic Surgery
  • Minimally Invasive Surgery
  • Minimally Invasive Thoracic Surgeries
  • Neonatal Surgery
  • Nissen Fundoplication
  • Nuss Procedure / Minimally Invasive Repair of Pectus Excavatum
  • Pectus Carinatum Repair / Reconstruction
  • Pediatric General Surgery
  • Pediatric Surgical Oncology
  • Pediatric Thoracic Surgery
  • Percutaneous Endoscopic Gastrostomy (PEG)
  • Splenectomy
  • Video-Assisted Thoracic Surgery (VATS)
View all 19 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Pain
  • Antenatally Diagnosed Anomalies
  • Appendicitis
  • Birth Defects
  • Congenital Anomalies
  • Congenital Cystic Adenomatoid Malformation of the Lung (CCAM)
  • Congenital Malformations
  • Duodenal Atresia
  • Gallbladder Disease
  • Gastroesophageal Reflux (GERD)
  • Gastroschisis
  • Hernias
  • Hirschsprung's Disease
  • Hydrocele Hernia
  • Inflammatory Bowel Disease (IBD)
  • Intestinal Atresias
  • Malrotation
  • Necrotizing Enterocolitis
  • Omphalocele
  • Pectus Carinatum
  • Pectus Excavatum
  • Pediatric Cancer
  • Pediatric Hydrocele | Hernia
  • Pediatric Neonatal Disorders
  • Pediatric Tumors
  • Pulmonary Sequestration
  • Solid Tumor Disorders
  • Spina Bifida
  • Tracheoesophageal Fistula
  • Undescended Testicles
  • Wilms' Tumor
View all 31 Specialties +


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About John DiFiore, MD

John W. DiFiore, MD, FACS, FAAP, is Director of the Center of Excellence for Minimally Invasive Repair of Pectus Excavatum (Nuss procedure) and Surgical Director of the Fetal Care Center at Cleveland Clinic.

After graduating cum laude from Dartmouth College, Dr. DiFiore attended medical school at the Columbia University College of Physicians and Surgeons in New York City. He performed a surgical residency at New England Deaconess Hospital/Harvard Medical School, followed by a pediatric surgery and research fellowship at Boston Children's Hospital/Harvard Medical School in Boston. 

Dr. DiFiore is certified in general and pediatric surgery by the American Board of Surgery.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Children's Hospital of Boston
Pediatric Surgery
Boston, MA USA

Residency - New England Deaconess Hospital
Boston, MA USA

Fellowship - Children's Hospital of Boston
Research (Surgery)
Boston, MA USA

Residency - New England Deaconess Hospital
Boston, MA USA

Internship - New England Deaconess Hospital
Boston, MA USA

Medical Education - Columbia University College of Physicians & Surgeons at Harlem Hospital Center
New York, NY USA

Undergraduate - Dartmouth College
Hanover, NH USA

Professional Highlights

  • Surgical Director, Fetal Care Center, Cleveland Clinic
  • Director, Center of Excellence for Minimally Invasive Repair of Pectus Excavatum (Nuss procedure), Cleveland Clinic


  • Surgery - General Surgery
  • Surgery - Pediatric Surgery

Specialty Interests

congenital malformations, Director of Center of Excellence for Pectus excavatum, hernia, minimally invasive repair of pectus excavatum/Nuss procedure, Minimally Invasive Surgery, neonatal surgery, pediatric general surgery and thoracic surgery, pediatric solid tumors, pediatric surgical oncology, pediatric tumors, Surgical Director: Fetal Care Center

Awards & Honors

  • America's Top Surgeons, Pediatric Surgery
  • Jens G. Rosenkrantz Resident Research Award in Pediatric Surgery
  • Sidney Farber Award for Outstanding House Officer, Children’s Hospital, Boston


  • American Pediatric Surgical Association
  • American College of Surgeons
  • American Academy of Pediatrics
  • Central Surgical Association
  • International Fetal Medicine and Surgery Society
Research & Publications

Research & Publications

See publications for John DiFiore, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 1/4/2021, Dr. DiFiore has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

79 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.9 out of 5
Explains 4.9
Listens 4.9
Courtesy, Respect & Concern 5
Time Spent with Patient 4.8
Patient Rating of Doctor 5

30 Patient Comments

Reviewed on Nov 2, 2021

We love Dr. DiFiore! He is very thorough with our son's care, and Is very attentive to our questions and concerns.

Reviewed on Nov 2, 2021

We would highly recommend Dr. DiFiore to anyone looking for a pediatric surgeon to perform the Nuss Procedure to correct Pectus Excavatum.

Reviewed on Oct 26, 2021

Dr DiFiore was very informative and answered all our questions too. He took his time with us and is very caring.

Reviewed on Oct 26, 2021

Amazing Hospital, doctors, nurses, staff. Everything was so well organized. And the staff was so caring and kind. Very helpful as well.

Reviewed on Oct 6, 2021

Appointment times are a challenge, but I believe that is an outcome of the excellence Dr. DiFiore delivers. When you're as good as he is at what he does, you will be in demand.

Reviewed on Oct 6, 2021

Dr. DiFiore's bedside manner is outstanding, and it's clear he enjoys working with this age group. Additionally, he is willing and able to share is expertise and knowledge. His confidence is exactly what a parent needs to see when trusting their child's health to a surgeon.

Reviewed on Oct 4, 2021

Eric was very comfortable with Dr. DiFiore and felt he understood his feelings about his chest.

Reviewed on Aug 30, 2021

Dr DiFiorri saved my life and I am eternally grateful. He is amazing and is a top notch doctor.

Reviewed on Aug 16, 2021

Dr. DiFiore is hands down one of the best Doctors/Surgeons in this country.

Reviewed on Jul 26, 2021

Dr DiFiore is excellent and I would definitely recommend him to others

Reviewed on Jun 29, 2021

Dr. DiFiore was extremely knowledgeable, professional, and personable. Our family felt very comfortable to ask questions. We truly appreciated the time he spent with us.

Reviewed on Jun 28, 2021

Dr. DiFiore has an amazing bed side manner. He takes his time and answers all our questions. We expressed some concern over the timing of our procedure and he was able to work around our schedule. The best thing Dr. DiFiore does that I have not seen other doctors do is his follow up letter. The letter details exactly what the procedure needed will entail. Why it is needed, his opinion and advice based on his experience in the field. My husband was not able to attend the meeting, but after receiving Dr. DiFiore's follow up letter, he felt like he was there.

Reviewed on Jun 25, 2021

Dr. DiFiore exemplifies excellence in medical care, bedside manner and communication. Dr. DiFiore is in a league of his own and I wish he could be cloned!

Reviewed on Jun 25, 2021

during our appointment, my son felt faint and Dr. DiFiore was wonderful with him. he immediately laid him down, took my son's pulse and blood pressure (which had dropped significantly) and his staff brought juice and crackers to combat his feeling ill. Everyone was very attentive to my son in those moments, which gives me increased confidence as we prepare for his upcoming surgery.Once these moments passed, Dr. DiFiore resumed preparing us for Noah's upcoming surgery and answered all our questions. He was incredibly thorough.

Reviewed on Jun 25, 2021

One of my biggest concerns with this upcoming surgery is that my son's pain is well managed. Dr. DiFiore explained Cleveland Clinic Children's pain protocol which helped ease my fears. I am very hopeful that he will be conformist-op

Reviewed on Jun 21, 2021

great medical care provider

Reviewed on Jun 21, 2021

was a very good medical care provider, who took much concern into how the whole process from pre to post surgery both times very well overall great man.

Reviewed on Apr 2, 2021

Dr. Difore and his staff are amazing! always friendly and kind when we go visit. Too notch care all the way around!!

Reviewed on Mar 29, 2021

Dr. DiFiore is an exceptional doctor. We had high expectations going into the appointment because we had researched to find the best provider for our daughter's condition. He exceeded all of them! After feeling very nervous about how we should proceed with our daughter's problem, we left our appointment with Dr. DiFiore feeling comfortable, confident in our understanding, and that our daughter is in the most caring and experienced hands possible. We were amazed at the amount of time he spent with us, and how thoroughly he went over the specifics of our daughter's condition, explaining everything and answering our questions so that we fully understood. He was not in a hurry and he did not just share facts, but showed our daughter that he truly cares.

Reviewed on Mar 26, 2021

Dr.DiFiore was amazing. I could not have found a doctor I trust more with my daughter.

Reviewed on Mar 22, 2021

both Dr DiFiore and his resident were very professional and informative. I especially liked the way both men interacted with my 14 year old son. They engaged him and took his questions and concerns into consideration, as much they did as my husband and me.

Reviewed on Mar 12, 2021

The best doctor we've ever had. Dr DiFiore was extremely knowledgeable, patient, and kind. He explained everything and made our daughter feel comfortable and confident about her surgery.

Reviewed on Mar 10, 2021

Awesome doctor and staff.

Reviewed on Mar 10, 2021

Absolutely loved Dr.Difiore! Both he and his resident were amazing! best experience I've had with a physician for my children in a very long time.

Reviewed on Feb 12, 2021

It was a great experience for our daughter (& us). The doctor was the BEST and I would definitely recommend.

Reviewed on Jan 22, 2021

My son received exceptional care from Dr Difoire

Reviewed on Jan 20, 2021

experience with dr. Difiore and hospital staff day of surgery and following were excellent. thank you for making a difficult situation for my son more tolerable through your staffs care.

Reviewed on Jan 20, 2021

Dr. DiFiore is excellent with his patience and their parents. He seems genuinely concerned about my son's progress, he patiently answers all our questions, and he works hard to engage my quiet teenage son.

Reviewed on Dec 16, 2020

Dr. DiFiore's care has always been exceptional.

Reviewed on Dec 16, 2020

Dr Difiore is outstanding.. very caring and compassionate.. would recommend him.

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