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Department Pediatric Surgery
Primary Location Cleveland Clinic Main Campus
Type of Doctor Children & Adolescents Only
Languages English
Surgeon Yes
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Appendectomy
  • Childrens Primary Care
  • Department of Pediatric Surgery
  • Evaluation/Treatment of Antenatally Diagnosed Congenital Anomalies
  • Evaluation/Treatment of Pulmonary Sequestration / CCAM
  • Fundoplication Procedure for Children
  • Laparoscopic Surgery
  • Minimally Invasive Surgery
  • Minimally Invasive Thoracic Surgeries
  • Neonatal Surgery
  • Nissen Fundoplication
  • Nuss Procedure / Minimally Invasive Repair of Pectus Excavatum
  • Pectus Carinatum Repair / Reconstruction
  • Pediatric General Surgery
  • Pediatric Surgical Oncology
  • Pediatric Thoracic Surgery
  • Percutaneous Endoscopic Gastrostomy (PEG)
  • Splenectomy
  • Video-Assisted Thoracic Surgery (VATS)
View all 19 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Pain
  • Antenatally Diagnosed Anomalies
  • Appendicitis
  • Birth Defects
  • Congenital Anomalies
  • Congenital Cystic Adenomatoid Malformation of the Lung (CCAM)
  • Congenital Malformations
  • Duodenal Atresia
  • Gallbladder Disease
  • Gastroesophageal Reflux (GERD)
  • Gastroschisis
  • Hernias
  • Hirschsprung's Disease
  • Hydrocele Hernia
  • Inflammatory Bowel Disease (IBD)
  • Intestinal Atresias
  • Malrotation
  • Necrotizing Enterocolitis
  • Omphalocele
  • Pectus Carinatum
  • Pectus Excavatum
  • Pediatric Cancer
  • Pediatric Hydrocele | Hernia
  • Pediatric Neonatal Disorders
  • Pediatric Tumors
  • Pulmonary Sequestration
  • Solid Tumor Disorders
  • Spina Bifida
  • Tracheoesophageal Fistula
  • Undescended Testicles
  • Wilms' Tumor
View all 31 Specialties +


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About John DiFiore, MD

John W. DiFiore, MD, FACS, FAAP, is Director of the Center of Excellence for Minimally Invasive Repair of Pectus Excavatum (Nuss procedure) and Surgical Director of the Fetal Care Center at Cleveland Clinic.

After graduating cum laude from Dartmouth College, Dr. DiFiore attended medical school at the Columbia University College of Physicians and Surgeons in New York City. He performed a surgical residency at New England Deaconess Hospital/Harvard Medical School, followed by a pediatric surgery and research fellowship at Boston Children's Hospital/Harvard Medical School in Boston. 

Dr. DiFiore is certified in general and pediatric surgery by the American Board of Surgery.
Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Children's Hospital of Boston
Pediatric Surgery
Boston, MA USA

Residency - New England Deaconess Hospital
Boston, MA USA

Fellowship - Children's Hospital of Boston
Research (Surgery)
Boston, MA USA

Residency - New England Deaconess Hospital
Boston, MA USA

Internship - New England Deaconess Hospital
Boston, MA USA

Medical Education - Columbia University College of Physicians & Surgeons at Harlem Hospital Center
New York, NY USA

Undergraduate - Dartmouth College
Hanover, NH USA

Professional Highlights

  • Surgical Director, Fetal Care Center, Cleveland Clinic
  • Director, Center of Excellence for Minimally Invasive Repair of Pectus Excavatum (Nuss procedure), Cleveland Clinic


  • Surgery - General Surgery
  • Surgery - Pediatric Surgery

Specialty Interests

congenital malformations, Director of Center of Excellence for Pectus excavatum, hernia, minimally invasive repair of pectus excavatum/Nuss procedure, Minimally Invasive Surgery, neonatal surgery, pediatric general surgery and thoracic surgery, pediatric solid tumors, pediatric surgical oncology, pediatric tumors, Surgical Director: Fetal Care Center

Awards & Honors

  • America's Top Surgeons, Pediatric Surgery
  • Jens G. Rosenkrantz Resident Research Award in Pediatric Surgery
  • Sidney Farber Award for Outstanding House Officer, Children’s Hospital, Boston


  • American Pediatric Surgical Association
  • American College of Surgeons
  • American Academy of Pediatrics
  • Central Surgical Association
  • International Fetal Medicine and Surgery Society
Research & Publications

Research & Publications

See publications for John DiFiore, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 12/7/2021, Dr. DiFiore has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. DiFiore receives fees of $5,000 or more per year as a paid consultant, speaker or member of an advisory committee for the following companies:

  • AtriCure, Inc.
  • Biomet Microfixation

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

60 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
5 out of 5
Explains 5
Listens 4.7
Courtesy, Respect & Concern 5
Time Spent with Patient 4.6
Patient Rating of Doctor 5

19 Patient Comments

Reviewed on Mar 30, 2022

Dr Difiore was very knowledgeable, kind and very thorough.

Reviewed on Mar 28, 2022

Dr Difiori is an excellent doctor and very attentive to our questions

Reviewed on Mar 28, 2022

We are so grateful for the knowledge and kindness of Dr. DiFiore

Reviewed on Mar 1, 2022

Dr Difiore is an amazing surgeon and he communicates with his patient and the parents very well! Answers all questions and is very professional, informative and kind.

Reviewed on Jan 19, 2022

Dr. DiFiore was so good at explaining the test results to my son and I.

Reviewed on Dec 29, 2021

Doctor and his team are great!! Highly recommend!

Reviewed on Dec 20, 2021

If I could give Dr. DiFiore a higher score-- Excellent or Superb- I would. I have been to other doctors with my son about his condition and we have asked the same questions. Dr. DiFiore's explanations went far beyond the explanations of other doctors at other facilities. He took every question seriously, did not rush, and explained so that both I and my son understood. His follow-up letter to my son's pediatrician was similarly comprehensive and clear.

Reviewed on Nov 15, 2021

Dr. Difiore was amazing! He took time to thoroughly examine our son, discuss his findings and treatment option. Would highly recommend him!

Reviewed on Nov 12, 2021

Dr. Difiore is the best!

Reviewed on Nov 8, 2021

Dr. DiFiore is amazing. We are thrilled with the results of our son's surgery and both the pre and follow-up care he has received! Dr. DiFiore is respectful and thorough in his explanations. He makes my son feel at ease and answers all our questions - usually before we even have to ask. We appreciate his Incredible surgical skills abs are looking forward to a healthy future! Also, Jill is just wonderful. She worked closely with us to manage my son's pain post surgery and always promptly returned calls and emails. We appreciate the extra time she has shared with us throughout this experience.

Reviewed on Nov 2, 2021

We love Dr. DiFiore! He is very thorough with our son's care, and Is very attentive to our questions and concerns.

Reviewed on Nov 2, 2021

We would highly recommend Dr. DiFiore to anyone looking for a pediatric surgeon to perform the Nuss Procedure to correct Pectus Excavatum.

Reviewed on Oct 26, 2021

Dr DiFiore was very informative and answered all our questions too. He took his time with us and is very caring.

Reviewed on Oct 26, 2021

Amazing Hospital, doctors, nurses, staff. Everything was so well organized. And the staff was so caring and kind. Very helpful as well.

Reviewed on Oct 6, 2021

Appointment times are a challenge, but I believe that is an outcome of the excellence Dr. DiFiore delivers. When you're as good as he is at what he does, you will be in demand.

Reviewed on Oct 6, 2021

Dr. DiFiore's bedside manner is outstanding, and it's clear he enjoys working with this age group. Additionally, he is willing and able to share is expertise and knowledge. His confidence is exactly what a parent needs to see when trusting their child's health to a surgeon.

Reviewed on Oct 4, 2021

Eric was very comfortable with Dr. DiFiore and felt he understood his feelings about his chest.

Reviewed on Aug 30, 2021

Dr DiFiorri saved my life and I am eternally grateful. He is amazing and is a top notch doctor.

Reviewed on Aug 16, 2021

Dr. DiFiore is hands down one of the best Doctors/Surgeons in this country.

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