Emergency icon Important Updates
Department Pain Management
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages English
Surgeon No
Locations Specialties & Treatments

Treatment & Services

  • Abdominal Wall Block
  • Back Pain Treatment
  • Bursa Injection
  • Celiac Plexus Block
  • Cervical Facet Joint Block
  • Diagnostic Epidural Differential Blocks
  • Discograms
  • Dorsal Root Ganglion (DRG) Stimulation Therapy
  • Epidural Blood Patch
  • Epidural Steroid Injection
  • Fluoroscopy-Guided Interventional Pain Management
  • Foot Injection
  • Ganglion Impar Block
  • Hand Injection
  • Hip Injection
  • Hypogastric Plexus Block
  • Implantable Intrathecal Drug Delivery Systems
  • Implantable Spinal Cord Stimulator Therapy
  • Intradiscal Intervention
  • Intradiscal Procedure for Pain Relief
  • Joint Injections
  • Knee Injections
  • Kyphoplasty
  • Lumbar Facet Joint Block
  • Lumbar Sympathetic Block
  • Medial Branch Blocks
  • Minimally Invasive Lumbar Decompression
  • Neck Pain Treatment
  • Nerve Blocks
  • Neuromodulation
  • Pain Management
  • Radiofrequency Ablation
  • Sacroiliac Joint Injections
  • Second Opinion Neuropathic Pain
  • Selective Nerve Root Injection
  • Shoulder Injection
  • Sphenopalatine Ganglion (SPG) Blocks
  • Splanchnic Nerve Block
  • Stellate Ganglion Block
  • Sympathetic Nerve Blocks
  • Thoracic Facet Joint Block
  • Transforaminal Injections
  • Trigeminal Nerve Blocks
  • Trigeminal Nerve Radiofrequency Ablation
  • Trigger Point Injection
  • Ultrasound-Guided Joint Injections
  • Ultrasound-Guided Peripheral Nerve Blocks
View all 47 Treatment & Services +

Specialty in Diseases & Conditions

  • Abdominal Pain
  • Arachnoiditis
  • Back Pain
  • Brachial Plexopathy
  • Burning Mouth
  • Bursitis
  • Cancer Pain
  • Causalgia
  • Cervical Facet Syndrome
  • Cervical Radiculopathy
  • Cervical Spondylosis
  • Chemotherapy-Induced Neuropathy
  • Chest Wall Pain
  • Chronic Back Pain
  • Chronic Postsurgical Pain
  • Complex Regional Pain Syndrome
  • Facet Joint Syndrome
  • Facial Pain
  • Failed Back Surgery Syndrome
  • Fibromyalgia
  • Foot Pain
  • Glossopharyngeal Neuralgia
  • Headaches
  • Herniated Disc
  • Hip Pain
  • Intercostal Neuralgia
  • Interstitial Cystitis
  • Knee Pain
  • Migraine Headaches
  • Musculoskeletal Pain
  • Myofascial Pain Syndrome
  • Neck Pain
  • Nerve Injuries
  • Neuropathic Pain
  • Neuropathy
  • Neuropathy - Diabetic
  • Occipital Neuralgia
  • Orofacial Pain
  • Painful Diabetic Neuropathy
  • Phantom Limb Pain
  • Piriformis Syndrome
  • Post Thoracotomy Pain
  • Post-Herpetic Neuralgia
  • Post-Laminectomy Syndrome
  • Postlaminectomy Syndrome Lumbar
  • Post-Surgical Pain Syndromes
  • Radiculopathy
  • Reflex Sympathetic Dystrophy (RSD)
  • Sacroiliac Joint Dysfunction
  • Sacroiliitis
  • Sciatica
  • Shoulder Pain
  • Spinal Stenosis
  • Spine Pain
  • Spondylitis
  • Superior and Inferior Orbital Neuralgia
  • Temporomandibular Disorders
  • Trigeminal Neuralgia
  • Vertebral Compression Fracture
View all 59 Specialties +


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About Jijun Xu, MD, PhD

Jijun Xu, MD, PhD is board-certified in Anesthesiology and Pain Medicine, and holds joint appointments in the Department of Pain Management and the Department of Inflammation and Immunity. He is an Associate Professor of Anesthesiology at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Dr. Xu specializes in interventional pain management. His research interests include clinical outcomes and basic science of neuropathic pain. He is involved in multiple clinical trials at Cleveland Clinic. He is the Principal Investigator (PI) of the SENZA-PDN (Spinal cord stimulation for refractory painful diabetic neuropathy) trial. He is also investigating the use of Nitrous Oxide in Complex Regional Pain Syndrome (CRPS). He is the PI or co-PI of NIH-funded research projects on Chemotherapy-induced Peripheral Neuropathy and CRPS. He serves on the Research Committee of the American Academy of Pain Medicine. He is an invited speaker at international and national conferences.

Dr. Xu is passionate about incorporating new advances in pain management into clinical practice, conducting cutting-age research, and teaching residents and fellows. He was selected as the “Best Teacher” and the “Cleveland Clinic Pain Medicine Staff of the Year” in 2016 and 2020.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Fellowship - Cleveland Clinic
Pain Medicine
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Medical Education - University of Texas M.D. Anderson Cancer Center
Pain Medicine
Houston, TX USA

Medical Education - University of Texas Health Science Center at Houston
Neuroscience and Genes and Development
Houston, TX USA

Graduate School - Nanjing Medical College
Microbiology and Immunology


Residency - Nantong University College of Medicine

Medical Education - Nantong University College of Medicine

Additional Training

  • Ph.D. in Neuroscience and Genes & Development; Opioid tolerance, Graduate School of Biomedical Sciences (GSBS), The University of Texas Health Science Center at Houston, The University of Texas (UT) M.D. Anderson Cancer Center, Houston, TX 2002-2007

    Postdoctoral Fellow, Inflammatory and Neuropathic Pain, Department of Anesthesiology and Pain Medicine, UT MD Anderson Cancer Center, TX 2007-2009


  • Anesthesiology - Pain Medicine
  • Anesthesiology

Specialty Interests

Neuropathic Pain, Complex Regional Pain Syndrome, Chronic Back and Neck Pain, Musculoskeletal Pain, Abdominal and Pelvic Pain, Headache and Facial Pain, Cancer Pain, Acute Postoperative Pain

Awards & Honors

  • 2023 Review Editor, Frontiers in Human Neuroscience – Sensory Neuroscience
  • 2021 Merit of Distinction Abstract, American Academy of Neurology (AAN)
  • 2020 Best of the Meeting Award, the 19th Annual meeting, American Society of Regional Anesthesia and Pain Medicine (ASRA)
  • 2020 Best Pain Abstract, Congress of Neurological Surgeons (CNS)
  • 2020 “Best Teacher” and “Cleveland Clinic Pain Medicine Staff of the Year”
  • 2020 NIH NCI grant “Complement in Chemotherapy-induced Peripheral Neuropathy”
  • 2020 NIH Study section panel “Somatosensory and Pain System”
  • 2016 “Best Teacher” and “Cleveland Clinic Pain Medicine Staff of the Year”
Research & Publications

Research & Publications

See publications for Jijun Xu, MD, PhD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 2/1/2023, Dr. Xu has reported no financial relationship with industry that is applicable to this listing. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

44 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.6 out of 5
Explains 4.5
Courtesy, Respect & Concern 4.7
Patient Rating of Doctor 4.6

9 Patient Comments

Reviewed on Feb 12, 2024

Dr. Xu has good bedside manner. He took the time to understand my pain complications due to surgery.

Reviewed on Feb 12, 2024

Dr. Xu is the best doctor I have ever seen at CCF

Reviewed on Dec 20, 2023

Dr Xu ignored and refused to answer questions, proposed a possible resolution that was not only illogical, but did not address the actual issue that was being presented. At one point he walked out of the room while I was in mid sentence talking with him.

Reviewed on Dec 1, 2023

It's just difficult to schedule with the dr. He's extremely popular and very good at what he does

Reviewed on Dec 1, 2023

Dr. Xu showed concern, knowledge and compassion for the pain I have been dealing with since knee replacement and offered some good recommendations. He sat WITH me to listen and discuss my situation rather than sitting at a computer. He had someone else taking the notes on the computer. I would like to see more doctors doing visits this way. Too many doctors at the Clinic are sitting at a computer typing rather than actually listening to the patient.

Reviewed on Nov 24, 2023

Dr Xu is the BEST

Reviewed on Aug 30, 2023

Dr XU is so great very caring and helpful to my illness. Has a lot of empathy and he try's to help in anyway he can.

Reviewed on May 22, 2023

Both doctors were very helpful and wanted the best for me

Reviewed on May 22, 2023

Dr. Xu and his staff are excellent. They take their time and listen to any issues or problems and think out of the box, when needed, to try to come up with solutions to help the patient.

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