alert icon Important Updates

Coming to a Cleveland Clinic location?
Hillcrest Cancer Center check-in changes
Cole Eye entrance closing
Visitation and COVID-19 information

Department Center for Neuro-Restoration
Primary Location Cleveland Clinic Main Campus
Type of Doctor Adults Only
Languages Arabic, English, French, German
Surgeon No
Cleveland Clinic Main Campus
Primary Location

Cleveland Clinic Main Campus


Additional Locations

Specialties & Treatments

Treatment & Services

  • Botulinum Toxin Injections
  • Infusion Therapy
  • Nerve Blocks
  • Occipital Nerve Block
  • Trigger Point Injection
View all 5 Treatment & Services +

Specialty in Diseases & Conditions

  • Chronic Headaches
  • Cluster Headaches
  • Facial Pain
  • Headaches
  • Intracranial Hypertension
  • Migraine Headaches
  • Occipital Neuralgia
  • Paroxysmal Hemicrania
  • Tension Headaches
  • Thunderclap Headaches
  • Trigeminal Neuralgia
View all 11 Specialties +


Is Cleveland Clinic Part of Your Insurance?

Review a list of accepted insurance plans for our Northeast Ohio locations or learn more about purchasing a contracted managed care plan.

View All Plans

About Emad Estemalik, MD

Emad Estemalik MD, MBA is the Chair for International Business Development at Cleveland Clinic’s International Operations, Section Head for Headache and Facial Pain at Cleveland Clinic’s Neurological Institute and Assistant Professor of Neurology at the Lerner School of Medicine of Case Western Reserve University.

He joined Cleveland Clinic as Staff in 2013. He is board certified by the American Board of Psychiatry and Neurology and Headache Medicine by the United Council for Neurological Subspecialties. He is a member of the American Headache Society.

Dr. Estemalik completed his residency at Cleveland Clinic in 2012. He also completed a one-year fellowship in headache medicine following his residency. He received his MD from the Ain Shams medical school in Cairo, Egypt in 2005. He also holds an MBA from the Weatherhead School of Management at Case Western Reserve University.

Dr. Estemalik leads the efforts of expanding Cleveland Clinic’s global outreach to enhance the enterprise’s international presence, direct its international resources towards building quality relationships with global healthcare institutions and identify strategic market opportunities to direct investment strategies.

Dr. Estemalik also serves on the leadership committee of Cleveland Clinic’s Neurological Institute (NI). His role includes executing Cleveland Clinic’s vision and helping achieve a high-performing institute while integrating education, research and medical innovation. His focus is to enhance the capabilities of medical informatics while directing NI’s programmatic domestic and international growth and further enhance the development of service lines that better serve patients. He also sits on NI’s marketing and philanthropy committee.

Dr. Estemalik speaks Arabic, German, French and Spanish. Born in Cairo, Egypt, he lived in various countries of the Middle East in addition to several years in Hamburg, Germany.

Dr. Estemalik’s areas of interests are migraine headaches, trigeminal autonomic cephalgias and facial neuralgias. He is a national and international speaker on various topics of headache disorders and its comorbidities. He is an active participant in various headache clinic trials at Cleveland Clinic. He is an active reviewer for Cleveland Clinic Journal of Medicine, Pain Practice Journal and the Egyptian Journal of Neurology and Neurosurgery. He consults and serves on faculty advisory boards of Lundbeck, Lilly, AbbVie and Teva pharmaceuticals.

Education & Professional Highlights

Education & Professional Highlights


Education & Fellowships

Graduate School - Case Western Reserve University
Cleveland, OH USA

Fellowship - Cleveland Clinic
Headache and Facial Pain
Cleveland, OH USA

Residency - Cleveland Clinic
Cleveland, OH USA

Internship - Ain Shams University Hospital
Cairo, Egypt

Medical Education - Ain Shams University Faculty of Medicine
Cairo, Egypt


  • Psychiatry and Neurology - Psychiatry
  • Headache Medicine

Specialty Interests

Migraines ;TACs ; Botox injections for chronic migraines and Trigeminal neuralgias ; Occipital nerve blocks ; Trigger point injections

Research & Publications

Research & Publications

See publications for Emad Estemalik, MD.

(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)

Industry Relationships

Industry Relationships

Cleveland Clinic physicians and scientists may collaborate with the pharmaceutical or medical device industries to help develop medical breakthroughs or provide medical expertise or education. Cleveland Clinic strives to make scientific advances that will benefit patient care and support outside relationships that promise public benefit. In order for the discoveries of Cleveland Clinic physicians' and scientists' laboratories and investigations to benefit the public, these discoveries must be commercialized in partnership with industry. As experts in their fields, Cleveland Clinic physicians and scientists are often sought after by industry to consult, provide expertise and education.

To assure professional and commercial integrity in such matters, Cleveland Clinic maintains a program that reviews these collaborations and, when appropriate, puts measures in place to minimize bias that may result from ties to industry. Cleveland Clinic publicly discloses the names of companies when (i) its physicians/scientists receive $5,000 or more per year (or, in rare cases, equity or stock options) for speaking and consulting, (ii) its physicians/scientists serve as a fiduciary, (iii) its physicians/scientists receive or have the right to receive royalties or (iv) its physicians/ scientists hold any equity interest for the physician's/scientist's role as inventor, discoverer, developer, founder or consultant.* In publicly disclosing this information, Cleveland Clinic tries to provide information as accurately as possible about its physicians' and scientists' connections with industry.

As of 7/14/2021, Dr. Estemalik has reported the financial relationships with the companies listed below. In general, patients should feel free to contact their doctor about any of the relationships and how the relationships are overseen by Cleveland Clinic. To learn more about Cleveland Clinic's policies on collaborations with industry and innovation management, go to our Integrity in Innovation page.

Consulting and/or Speaking. Dr. Estemalik receives fees of $5,000 or more per year (or, in rare cases, equity or stock options) as a paid consultant, speaker or as a member of an advisory committee for the following companies:

  • Lilly USA, LLC
  • Teva Pharmaceutical Industries, Ltd.
  • Allergan, Inc

Public Health Service-Reportable Financial Conflicts of Interest. Cleveland Clinic scientists and physicians engage in basic, translational and clinical research activities, working to solve health problems, enhance patient care and improve quality of life for patients. Interactions with industry are essential to bringing the researchers' discoveries to the public, but can present the potential for conflicts of interest related to their research activities. Click here to view a listing of instances where Cleveland Clinic has identified a Public Health Service (PHS)-Reportable Financial Conflict of Interest and has put measures in place to ensure that, to the extent possible, the design, conduct and reporting of the research is free from bias.

* Cleveland Clinic physicians and scientists subscribe to the guidance presented in the PhRMA Code on Interactions with Healthcare Professionals and the AdvaMed Code of Ethics on Interactions with Health Care Professionals. As such, gifts of substantial value are generally prohibited.

Patient Satisfaction Reviews

112 Patient Satisfaction Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

The comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Cleveland Clinic.

Overall Star Ratings
4.6 out of 5
Explains 4.5
Courtesy, Respect & Concern 4.6
Patient Rating of Doctor 4.5

16 Patient Comments

Reviewed on Aug 14, 2023

Dr.E is the best. He listens and asks questions while I get my injections. Because of him I have a life.

Reviewed on Jul 17, 2023

Dr. Estamalik was fantastic and offered me options to relieve pain I had been dealing with for 3 weeks.

Reviewed on Jun 7, 2023

Dr. E. Is very friendly and helpful. Injection technique is more efficient and less painful than others.

Reviewed on May 1, 2023

Dr Estamalik always makes time to listen.

Reviewed on Apr 24, 2023

He is very down to earth. He is very nice and cares about his patients. I would say he is the best doctor that I have

Reviewed on Apr 24, 2023

Dr Estamalik is always in a rush, I get the feeling he is distracted, not really listening, I don't think he is focused on the patientHe has been this way for years (very inpatient, abrupt). The way this translates is that he just wants to get the appointment over and has very little to propose in terms of possible treatment options

Reviewed on Apr 17, 2023

The doctor listened and gave very good advice.

Reviewed on Mar 7, 2023

Dr was amazing!

Reviewed on Jan 17, 2023

This doctor was amazing, truly amazing. I have been searching for years for a doctor to address my situation.

Reviewed on Jan 9, 2023

Great doctor

Reviewed on Jan 4, 2023

Dr Estermalic was most helpful. His professional and caring attitude toward me as a patient should serve as a template for the Cleveland Clinic.

Reviewed on Dec 16, 2022

Dr. Estamalik listened to my concerns and we came up with a plan for my care. I felt included in my care

Reviewed on Oct 31, 2022

Amazing staff and doctor

Reviewed on Oct 17, 2022

Dr. Estemalik is a very professional, kind, and warm physician!

Reviewed on Oct 3, 2022

Excellent experience with Dr. Estermalik

Reviewed on Sep 19, 2022

Best doctor and nurse...very nice, professional, smart and helpful

Back to Top