Risus sardonicus is when your facial muscles cause a painful, fixed smile and arched eyebrows. Causes include certain bacterial infections, neurological disorders and neurotoxic poisoning. Treatment depends on the cause, but often includes antibiotics, antitoxins and muscle relaxers.
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Risus sardonicus (rye-sus sar-dan-uh-kes) is when the muscles in your face tighten, forcing a big, open-mouth smile and raised eyebrows. Some people describe it as a sneer. It’s a type of painful, involuntary muscle spasm.
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But it isn’t like spasms that occur in other parts of your body. Those can occur due to dehydration, overuse or sitting too much. Instead, risus sardonicus usually happens from a certain type of bacterial infection. It can also result from particular genetic conditions and exposure to certain poisons.
“Risus” is Latin for “laugh.” “Sardonicus” comes from the Greek word “sardónios,” which means a bitter or scornful laugh or smile. Other names for risus sardonicus include:
The most common cause of risus sardonicus is tetanus. Tetanus is a bacterial infection. It causes muscle spasms, especially in your head, neck and face.
Other possible risus sardonicus causes include:
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Risus sardonicus treatment depends on the cause.
Tetanus treatment generally includes medications, such as:
Healthcare providers may recommend muscle relaxers to help reduce spasms. You may also need benzodiazepines (benzos) to slow down your nervous system.
If you have strychnine poisoning, it’s important to get it out of your system as quickly as possible. Treatment usually includes:
If Wilson disease causes risus sardonicus, providers may recommend botulinum toxin (Botox®) injections. They’ll inject Botox around your mouth and eyebrows.
The causes of risus sardonicus are life-threatening without treatment. Get help as soon as possible if your face locks into a big smile and raised eyebrows.
You can’t prevent all risus sardonicus causes, like Wilson disease. But you can avoid other causes by:
Call 911 (or your local emergency service number) or get to the nearest ER immediately if you have painful facial muscle spasms. Healthcare providers can help diagnose and treat the cause of risus sardonicus.
Trismus is also a type of facial muscle spasm. But unlike risus sardonicus, trismus prevents you from opening up your mouth as wide as usual. Tetanus and other infections can cause trismus. But the main causes are head and neck cancer treatments and dental surgery.
Risus sardonicus forces your mouth into a big, permanent grin and arches your eyebrows. But it isn’t an expression of happiness. It’s usually painful, and it can be downright scary to lose control of your facial muscles. The causes are serious, and they need urgent medical attention. The sooner you get help, the better your chances of a good outcome.
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Last reviewed on 10/27/2025.
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