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Renal Vein Thrombosis

Medically Reviewed.Last updated on 04/27/2026.

Renal vein thrombosis is a rare condition involving a blood clot that forms in one of your kidney veins. Many people don’t have symptoms. They get a diagnosis when they have imaging for a different reason. Treatment may include medicine or a procedure. Your prognosis often depends on the cause.

What Is Renal Vein Thrombosis?

Anatomy of blood clot (thrombus) in a vein of a kidney, known as renal vein thrombosis
Renal vein thrombosis is a blood clot (thrombus) that happens in a vein that carries blood out of your kidney.

Renal vein thrombosis is a blood clot in a vein coming out of your kidney. The blood clot can partly or fully block your vein, limiting how much blood can get through. This rare condition often affects renal veins on both kidneys at once. But it’s more likely to happen in the left renal vein than the right. This is because the superior mesenteric artery can put pressure on the left renal vein.

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Renal vein thrombosis can be short term (acute) or long term (chronic). The acute type is more common in younger adults and includes symptoms. The chronic type is more likely to happen in older adults and often doesn’t cause symptoms.

Symptoms and Causes

Symptoms of renal vein thrombosis

You may have back, hip, flank or belly pain. You may also have blood in your pee (urine). But you may not have symptoms at first. Then, symptoms may be mild or grow little by little. In children and some adults, symptoms can start without warning.

Other renal vein thrombosis symptoms may include:

  • Nausea
  • Vomiting
  • Fever
  • A smaller amount of pee than usual
  • More resistant high blood pressure
  • Dull, aching pelvic pain that worsens with standing, sexual intercourse or menstruation in women
  • Dull, aching pain or heavy, dragging sensation in the scrotum in men that worsens with standing and improves when lying down
  • Swelling in your legs (rare)

Renal vein thrombosis causes

Most often, the cause of renal vein thrombosis is cancer or a release of too much protein into your pee (nephrotic syndrome). These can make you more likely to get blood clots.

Other causes include:

  • Blood clotting disorders
  • Lupus
  • Inflamed blood vessels (vasculitis)
  • Sickle cell disease affecting your kidneys
  • Diabetes affecting your kidneys
  • Injury
  • Kidney transplant
  • Cocaine use disorder
  • Oral contraceptive use
  • Infection
  • Pregnancy

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Risk factors

Renal vein thrombosis is more likely to happen in:

  • Males
  • People aged 30 to 60
  • Adults with nephrotic syndrome
  • Infants who have dehydration

Complications of this condition

Renal vein thrombosis can lead to:

  • High blood pressure
  • Swelling in your kidney
  • Kidney damage
  • Chronic kidney disease
  • A blood clot in your gonadal vein (near your testes or ovary)
  • A blood clot traveling to your lung (pulmonary embolism)

Diagnosis and Tests

How doctors diagnose renal vein thrombosis

You may not know you have this condition until it shows up on imaging to look for something else. Healthcare providers can diagnose this condition with the following tests:

Management and Treatment

How is it treated?

Healthcare providers start by treating the condition that caused renal vein thrombosis. They’ll want to get blood flowing well again in your kidney so it works better. Renal vein thrombosis treatment may include:

When should I see my healthcare provider?

Get medical care right away if you have symptoms of renal vein thrombosis or a hard time breathing. Trouble breathing could mean you have a pulmonary embolism, which can be a life-threatening condition.

Questions to ask your provider may include:

  • Which treatment is best for me?
  • What do I need to know about taking blood thinners?
  • How often do I need follow-up visits with you?
  • Is it possible for this condition to happen again?

Outlook / Prognosis

What can I expect if I have this condition?

After a healthcare provider removes or dissolves the blood clot, you may need to take blood thinners for six to 12 months. If you have kidney disease, you may take them even longer. You’ll also need to continue treatment for the disease that led to the clot.

You can expect to have follow-up visits with your provider several times during the first year after treatment. Then, you may have check-ups once a year.

With treatment, the prognosis is usually good. Your outlook depends on what caused the renal vein thrombosis and how much kidney damage you have. Complications also matter. For example, a pulmonary embolism can be fatal.

A note from Cleveland Clinic

It can be upsetting to learn that a medical condition you have has led to another one. It may feel like you can’t catch a break. But your healthcare provider has several treatment options to offer for renal vein thrombosis. Your provider can help you make your way through this stressful time and answer your questions as you go.

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Medically Reviewed.Last updated on 04/27/2026.

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References

Cleveland Clinic’s health articles are based on evidence-backed information and review by medical professionals to ensure accuracy, reliability and up-to-date clinical standards.

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